体育锻炼与老年人健康

参加有规律的体育锻炼能延缓衰老引起的身体机能的下降。耐力运动有助于维持和改善心血管机能,减小心血管危险因素;力量运动能补偿衰老引起的肌肉质量和力量的下降。因此,有规律的体育锻炼能改善老年人机能能力,有助于老年人有一个更加健康、独立的生活方式。     

Physical exercise in the prevention and treatment of Alzheimer's disease

Dementia is one of the greatest global challenges for health and social care in the 21st century. Alzheimer's disease (AD), the most common type of dementia, is by no means an inevitable consequence of growing old. Several lifestyle factors may increase, or reduce, an individual's risk of developing AD. Much has been written over the ages about the benefits of exercise and physical activity. Among the risk factors associated with AD is a low level of physical activity. The relationship between physical and mental health was established several years ago. In this review, we discuss the role of exercise (aerobic and resistance) training as a therapeutic strategy for the treatment and prevention of AD. Older adults who exercise are more likely to maintain cognition. We address the main protective mechanism on brain function modulated by physical exercise by examining both human and animal studies. We will pay especial attention to the potential role of exercise in the modulation of amyloid β turnover, inflammation, synthesis and release of neurotrophins, and improvements in cerebral blood flow. Promoting changes in lifestyle in presymptomatic and predementia disease stages may have the potential for delaying one-third of dementias worldwide. Multimodal interventions that include the adoption of an active lifestyle should be recommended for older populations.     

Clinical implications of exercise immunology

Maintaining leanness and a physically active lifestyle during adulthood reduces systemic inflammation, an underlying factor in multiple chronic diseases. The anti-inflammatory influence of near-daily physical activity in lowering C-reactive protein, total blood leukocytes, interleukin-6, and other inflammatory cytokines may play a key role in lowering risk of cardiovascular disease, certain types of cancer, type 2 diabetes, sarcopenia, and dementia. Moderate exercise training causes favorable perturbations in immunity and a reduction in incidence of upper respiratory tract infection (URTI). During each bout of moderate exercise, an enhanced recirculation of immunoglobulins, neutrophils, and natural killer cells occurs that persists for up to 3-h post-exercise. This exercise-induced surge in immune cells from the innate immune system is transient but improves overall surveillance against pathogens. As moderate exercise continues on a near-daily basis for 12–15 weeks, the number of symptoms days with URTI is decreased 25%–50% compared to randomized sedentary controls. Epidemiologic and animal studies support this inverse relationship between URTI risk and increased physical activity.     

Running for your life: A review of physical activity and cardiovascular disease risk reduction in individuals with schizophrenia

Individuals with schizophrenia have a greater risk for cardiometabolic risk factors (e.g. central obesity, insulin resistance, hypertension and dyslipidaemia), cardiovascular diseases and mortality. This risky profile may be explained by the adverse effects of antipsychotic medications and an unhealthy lifestyle (e.g. smoking, poor nutrition and low physical activity). In the general population, physical activity has been shown to be the optimal strategy to improve both cardiometabolic parameters and cardiorespiratory fitness levels. Accordingly, an emerging literature of non-pharmacological interventions (e.g. cognitive behavioural therapy, diet and physical activity) has been studied in individuals with schizophrenia. Therefore, the purpose of this review was 1) to conduct a critical literature review of non-pharmacological interventions that included some kind of physical activity (including supervised and unsupervised exercise training) and target cardiometabolic risk factors in individuals with schizophrenia. 2) To describe the contribution of physical activity alone by reviewing trials of supervised exercise training programmes only. A literature review via systematic keyword search for publications in Medline, PubMed, Embase and PsycINFO was performed. Many non-pharmacological interventions are efficient in reducing cardiovascular disease risk factors when combined with physical activity. Supervised physical activity has been successful in decreasing cardiovascular disease risk, and aerobic interval training appears to provide more benefits by specifically targeting cardiorespiratory fitness levels. In conclusion, physical activity is an effective strategy for addressing cardiovascular disease risk in individuals with schizophrenia. Long-term studies are needed to evaluate the feasibility and impact of exercise training programmes in individuals with schizophrenia.     

Nutritional strategies to counter stress to the immune system in athletes, with special reference to football

Although epidemiological data indicate that athletes are at increased risk of upper respiratory tract infection during periods of heavy training and the 1 - 2 week period following endurance race events, there is very limited information on the responses to football training and match-play. For several hours after heavy exertion, components of both the innate (e.g. natural killer cell activity and neutrophil oxidative burst activity) and adaptive (e.g. T and B cell function) immune system exhibit suppressed function. Although such responses to football training and competition do not appear to be as pronounced, variations in immune cell numbers and function are reported in professional footballers over the course of a season. Attempts have been made through nutritional means (e.g. glutamine, vitamins C and E, and carbohydrate supplementation) to attenuate immune changes following intensive exercise and thus lower the risk of upper respiratory tract infection. Carbohydrate supplementation during heavy exercise has emerged as a partial countermeasure and attenuates increases in blood neutrophil counts, stress hormones, and inflammatory cytokines, but has little effect on decrements in salivary IgA output or natural killer cell function. Animal research indicates that other nutritional components such as beta-glucan, quercetin, and curcumin warrant human investigations to determine if they are effective countermeasures to exercise-induced immune dysfunction.     

2021年中国健身趋势———针对国内健身从业人员的网络问卷调查

对健身趋势的预测能够为健身领域的企业主、俱乐部管理人员、课程研发人员、健身从业人员制定来年计划提供参考。2020年8月1日-31日面向国内健身从业人员进行了在线问卷调查。对3 368份有效问卷的分析表明,排名前20的2021年中国健身趋势分别为减重运动、健康饮食、运动与健康从业人士培训与认证、青少年体育、有氧健身、核心训练、私人训练、功能性健身、健康指导、健身专业人士的许可、运动损伤预防与康复、自由负重力量训练、户外活动、运动即良医、雇用认证健身专业人士、自重训练、健身结果测量、生活方式医学、小团体私人训练、移动设备运动APP。减重相关和经由行业机构推荐的健身趋势排名靠前,不同人群对应的健身趋势存在共性与差异。建议未来立足国内健身行业制定本土化调查问卷,并考虑按人群开展健身趋势调查。     

运动·上呼吸道感染和免疫

流行病学的研究结果指出大运动量训练和比赛后上呼吸道感染发病率增加,同时,对其发病机理及如何减少易感性疾病的发生作了概括的介绍。     

Recommendations to maintain immune health in athletes

Numerous studies over the last 35 years report an increase in upper respiratory infection (URI) symptoms in athletes during periods of heavy training and competition. Challenges athletes face such as heavy exercise and life stress influence immune function via activation of the hypothalamic–pituitary–adrenal axis and the sympathetic nervous system and the resulting immunoregulatory hormones. Both innate and acquired immunity are often reported to decrease transiently in the hours after heavy exertion, typically 15–70%: prolonged heavy training sessions in particular have been shown to decrease immune function; potentially providing an ‘open window’ for opportunistic infections. Whether the observed changes in immunity with acute strenuous exercise or periods of heavy training account for the increased susceptibility to URI symptoms remains contentious. Nevertheless, there is little doubt that URI symptoms hinder athletic training and competition; underpinning the need to identify the prominent risk factors and appropriate countermeasures. Recent studies have identified prominent risk factors, including: intensified training in the winter; long-haul travel; low energy availability; high levels of psychological stress and anxiety; and depression. Given the shared pathways and effector limbs for the body’s response to physical and psychological challenges, it is logical that psychological strain influences immunity and illness incidence in athletes under heavy training; indeed, stress and anxiety have recently been shown to modify the immune response to exercise. This mini-review provides new insights and evidence-based recommendations for coping with the various challenges that athletes encounter on immune health, including: heavy exercise; life stress; sleep disruption; environmental extremes and nutritional deficits.     

Coronavirus disease-2019: A tocsin to our aging,unfit, corpulent,and immunodeficient society

Acute and chronic respiratory illnesses cause widespread morbidity and mortality, and this class of illness now includes the novel coronavirus severe acute respiratory syndrome that is causing coronavirus disease-2019 (COVID-19). The world is experiencing a major demographic shift toward an older, obese, and physically inactive populace. Risk factor assessments based on pandemic data indicate that those at higher risk for severe illness from COVID-19 include older males, and people of all ages with obesity and related comorbidities such as hypertension and type 2 diabetes. Aging in and of itself leads to negative changes in innate and adaptive immunity, a process termed immunosenescence. Obesity causes systemic inflammation and adversely impacts immune function and host defense in a way that patterns immunosenescence. Two primary prevention strategies to reduce the risk for COVID-19 at both the community and individual levels include mitigation activities and the adoption of lifestyle practices consistent with good immune health. Animal and human studies support the idea that, in contrast to high exercise workloads, regular moderate-intensity physical activity improves immunosurveillance against pathogens and reduces morbidity and mortality from viral infection and respiratory illnesses including the common cold, pneumonia, and influenza. The odds are high that infectious disease pandemics spawned by novel pathogens will continue to inflict morbidity and mortality as the world's population becomes older and more obese. COVID-19 is indeed a wake-up call, a tocsin, to the world that primary prevention countermeasures focused on health behaviors and hygiene demand our full attention and support.     

竞技体育中运动负荷与损伤风险关系的研究进展

为通过科学调控运动训练来实现对运动损伤的有效控制,对运动负荷与损伤风险间关系的研究成为近些年体育科学领域的热点之一。长期训练使机体发生定向改造以适应专项特征,运动负荷刺激机能水平提高的同时也会使运动员发生损伤的风险产生变化,运动负荷与损伤风险具有一定的相关性。在绝对负荷中,负荷累积与损伤风险表现出剂量-效应关系;在相对负荷中,负荷变化对损伤风险具有一定的预测能力。为了降低损伤风险,在训练安排时应避免长时间使用较低水平负荷或使用极高水平负荷,以及避免负荷的过快增长。     

Immune function and exercise

This review will examine the effects of exercise and training on immune func-tion and will discuss the methodological problems that limit the interpretation of many exercise immunology studies. Acute bouts of exercise cause a tempo-rary depression of various aspects of immune function, such as neutrophil oxidative burst, lymphocyte proliferation, monocyte MHC class II expression, and natural killer cell cytotoxic activity, that will usually last for approximately three to 24 hours after exercise, depending on the intensity and duration of the exercise bout. Post-exercise immune function depression is most pronounced when the exercise is continuous, prolonged (<1.5 hours), of moderate to high intensity (55-75% VO₂max), and performed without food intake. Periods of intensified training that result in overreaching have been shown to chronically depress immune function—i.e., immune cell functions measured at rest are still depressed 24 hours after the last exercise bout. Although elite athletes are not clinically immune deficient, it is possible that the combined effects of small changes in several immune parameters may compromise resistance to common minor illnesses such as upper respiratory tract infection. Protracted immune depression linked with prolonged training may determine susceptibility to infection, particularly at times of major competitions.     

特殊人群的运动、感染风险和免疫机能

有关运动与免疫的研究,大都集中在研究运动对普通人群和运动员上呼吸道感染的影响以及免疫机能的影响,这些研究的大部分案例都是针对年轻人和健康人群的。那么,运动免疫学领域还很大,尤其是对那些疾病、亚健康和特殊年龄段的人群的研究仍是相对薄弱的地方。对特殊人群(HIV感染人群、老年人、儿童、肥胖和糖尿病)的运动、感染风险和免疫机能进行综述。     

运动与2型糖尿病治疗的研究述评

运动被认为是2型糖尿病（非胰岛素依赖型）病人治疗康复的基石，传统认为有氧耐力运动是最适宜的运动模式，目前许多研究发现抵抗性训练对治疗2型糖尿病也有效。因此，提出针对2型糖尿病人个体的最理想的运动方案应当是包括改善心肺功能、肌肉力量和耐力等的有氧耐力训练和抵抗性训练的综合方案，包括各种运动模式的运动方案都能积极地影响病人对运动方案的适应性。2型糖尿病人从事个性化的训练，发生并发症的危险性显著降低。     

Motives for lifestyle and exercise activities: A comparison using the theory of planned behaviour

Abstract

Regular exercise and lifestyle physical activity are often used interchangeably or combined in physical activity messaging based on evidence for their relatively equivalent health outcomes. However, differences between their motivational correlates are relatively unexplored. The purpose of this study was to compare the motives towards lifestyle physical activity and exercise and their relationship with behaviour using the Theory of Planned Behaviour (TPB). The participants were a sample of undergraduate students (n=150) who completed measures of the TPB framed in terms of exercise and lifestyle physical activity and self-reported physical activity measures with similar framing. Results identified marked differences between the instrumental attitudes towards the two activities showing instrumental attitudes towards exercise to be higher (P<0.01; d=0.68). Most importantly, exercise had larger TPB–behaviour correlations (P<0.01; q=0.15–0.20) compared with lifestyle physical activity, but follow-up analyses by intensity (strenuous, moderate, mild) showed that these differences were only present at strenuous intensity. Our results suggest that the correlates for the two types of physical activity may differ. Although more research is necessary, this may affect the efficacy of promotion campaigns that do not tailor content exclusively for either exercise or lifestyle physical activity.     

体适能教育理念对高校公共体育课程教学改革的影响

文章主要采取测试、调查、数理统计等研究方法,将体适能教育理念引人高校公共体育课教学改革。结果表明,"体适能"教育理念引入学校体育教学,在提高身体机能的同时,能引导大学生积极参加体育活动,增强自我主动锻炼意识,提高自我科学锻炼程度,能够帮助大学生更好地理解终身体育锻炼的价值、意义并养成良好的健康生活方式和行为习惯。     

谁有资格开运动处方,医生、运动健康博士、健身教练还是ChatGPT?

虽然“运动是良药”已被公共健康和临床医学所接受并付诸实践,谁有资格开运动处方仍是个具有争议的话题。本文从制定和应用运动处方“权威性”的角度对“谁有资格”进行了探索,认为虽然运动健康领域学者对运动处方的制定和发展作出了更多贡献,但目前运动和医务专业人士都不具备单独开具运动处方的能力,运动与医学跨学科融合的专业团队是开出科学、有效和个性化运动处方的必须条件,但目前不论在人才培养上还是专业组织架构上都存在巨大挑战。以ChatGPT为代表的新一代人工智能为应对挑战开辟了新方法和新路径,并已显示出了强大的生命力。可以预期,以人工智能为中心,以跨学科、个性化、疾病专业化、技术（可穿戴设备）和行为为理论基础,整合生活方式的新型运动处方体系即将到来。     

新疆乌鲁木齐市普通本科院校课外体育活动开展现状调查与分析

本文采用问卷调查法,文献资料法,访问调查法等方法,对新疆乌鲁木齐市普通本科院校学生参加课外体育锻炼的现状进行调查研究。从学生参加课外活动的平均次数、每次运动平均持续时间、不同季节学生参与课外体育活动情况和参与课外体育活动项目情况入手,在分析原因的基础上提出了建议。     

急性运动降低感染风险的免疫调节机制

由于新型冠状病毒(2019-nCoV)感染的肺炎疫情暴发,人们将居家运动作为提高免疫力与保持健康的重要手段,运动与免疫的关系再度受到关注。一般认为,在充分恢复的前提下进行规律的中高强度运动可提高免疫功能,而急性运动(acute exercise)可能抑制免疫功能并增加感染风险。急性运动后外周血淋巴细胞计数及功能降低、免疫球蛋白A水平分泌减少被认为是运动抑制免疫的理论基础。但目前这种独立于非运动因素影响免疫功能增加感染风险的认识受到了现有研究的挑战。急性运动可通过应激反应将淋巴细胞亚群迅速动员至循环中,运动结束后,淋巴细胞亚群又会迅速迁移至外周组织。淋巴细胞的重新分布(lymphocyte redeployment)可能是一种进化保守的免疫机制,这一过程强化了外周组织的免疫监视与调节功能,有助于提升机体抵抗感染能力。因此,从这一视角就急性运动对机会性感染风险及免疫功能影响的现状进行综述。     

Exercise and mental health: it's just not psychology!

Exercise has been suggested as an effective adjunctive treatment for a range of mental health conditions. In this study, we explored the perceptions of exercise held by course directors of doctoral training programmes in clinical psychology in England. Given the exploratory nature of the study, we used a qualitative design incorporating semi-structured interviews. Although most participants held favourable attitudes regarding exercise, this was related more to exercise being seen as a positive lifestyle activity that is worth encouraging, rather than exercise being recommended as an adjunctive treatment for mental health problems. Inductive analysis identified four themes that underpinned such a response: inconsistent positions on the evidential criteria used to evaluate the role of exercise, which masked themes regarding the perceived 'simplicity' of exercise interventions, a practical adherence to a mind-body dichotomy, and the incompatibility of exercise with traditional models of understanding and treating clinical conditions. The barriers we have highlighted will continue to hinder the consideration of exercise as a common therapeutic adjunct at present. Although further research is required to examine the relationship between exercise and mental health, consideration must also be given to how such research should be disseminated to mental health professionals.     

不同运动方式对绝经后女性IL-6、TNF-α和hs-CRP的影响

目的比较12周有氧运动或抗阻训练对绝经后女性白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)和高敏C-反应蛋白(hs-CRP)影响的差异,为制定特异性的运动处方提供依据。方法将符合标准的受试者随机分为有氧运动组(18人),抗阻训练组(17人)和对照组(20人)。有氧运动组和抗阻训练组进行每周3次、共12周的运动干预,对照组保持日常生活习惯不变。实验前后分别测定血清IL-6、TNF-α、hs-CRP等指标。结果 12周运动干预后,有氧运动组血清IL-6较运动前下降了13%(P<0.01),血清TNF-α(P>0.05)和hs-CRP(P>0.05)无显著性变化;抗阻训练组血清IL-6较运动前无显著性变化(P>0.05),但血清TNF-α和hs-CRP分别下降了11%(P<0.05)和26%(P<0.05)。对照组所有指标的变化不明显。相关分析显示,实验前hs-CRP基础值与BMI(r=0.36,P<0.01)、空腹血糖(r=0.23,P<0.05)和IL-6(r=0.22,P<0.01)正相关,与VO2max(r=-0.29,P<0.05)负相关;实验后hs-CRP的变化值与BMI的变化值(r=0.21,P<0.05)正相关。结论 绝经妇女慢性全身性炎症状态与其BMI、血糖水平和体内炎症因子的水平有关;12周有氧运动或抗阻训练均能有效改善绝经后女性慢性全身性炎症状态,但抗阻训练的效果优于有氧运动,其原因与BMI的改善有关。