驱虫药甲苯咪唑、丙硫咪唑的热分析研究

目的:研究了氨基甲酸甲酯类的甲苯咪唑和丙硫咪唑热分解特征.方法:应用TG、DTA、%TG方法进行热分析及动力学研究.结果:对甲苯咪唑和丙硫咪唑在空气介质中的热分解特征进行了定性、定量表征.结论:热分析方法可作为氨基甲酸甲酯类驱虫药的一种快速、简便的检验方法.     

左旋咪唑、甲苯咪唑及丙硫咪唑对体外短小绦虫卵的作用

目的观察不同浓度的左旋咪唑、甲苯咪唑及丙硫咪唑对短小绦虫卵的破坏作用.方法从虫体孕节中涮出虫卵,放入不同浓度的药液中,按时观察形态变化.结果左旋咪唑对虫卵破坏作用大于甲苯咪唑及丙硫咪唑.结论三种药物对虫卵都有破坏性.     

吡喹酮、甲苯咪唑和阿苯哒唑对微小膜壳绦虫作用的形态学观察

应用形态学方法,对比观察了吡喹酮、甲苯咪唑和阿苯哒唑对微小膜壳绦虫的杀伤作用。结果表明:吡喹酮作用强而迅速,虫体表皮破损,节片严重溃蚀;甲苯咪唑和阿苯哒唑的作用较弱而缓慢,为临床用药提供了参考。对三种药物的作用机制进行了探讨。     

常用驱蛔虫药的疗效观察

对207例患有肠道蛔虫病的患儿进行随机用药,分别给予左旋咪唑、肠虫清、驱虫丹、驱蛔灵治疗、其有效率分别为:87.5％、50％、49％、18.8％。以左旋咪唑疗效最佳,副作用最小,并且药物剂型小、给药方便、容易被患儿接受,是一种良好的驱虫药。肠道蛔虫病是小儿常见的肠道寄生虫病,以农村地区高发,往往引起小儿食欲不     

烷基咪唑离子液体与甲苯相互作用的理论研究

在密度泛函理论中的B3LYP/6-31G(d,p)水平上研究了1-乙基-3-甲基咪唑四氟硼酸盐([EMIM][BF4])离子液体与甲苯相互作用的微观机制.研究结果表明,[EMIM]+和[BF4]-离子对有两种稳定的构型,存在强的氢键及静电作用,[BF4]-离子靠近咪唑环2位H的构型比[BF4]-离子靠近咪唑环4、5位H处的构型稳定.甲苯与这两种构型的[EMIM][BF4]离子对形成π配位作用的分子复合物,咪唑环2位H对甲苯的吸附作用比咪唑环4、5位H对甲苯的吸附作用强,2位H表现出更高的活性.离子液体的存在能有效地降低甲苯的前线轨道能级差,表明甲苯在离子液体环境中更易发生催化反应.     

吡喹酮、阿苯哒唑和甲苯咪唑对微小膜壳绦虫作用的超微结构观察

目的观察吡喹酮、阿苯哒唑和甲苯咪唑对体外培养微小膜壳绦虫的作用。方法利用透射电镜对比观察吡喹酮、阿苯哒唑和甲苯咪唑作用于微小膜壳绦虫72h后的超微结构变化。结果吡喹酮、阿苯哒唑、甲苯咪唑对微小膜壳绦虫微毛、皮层、基底膜、肌层、实质组织层均有破坏作用,吡喹酮对虫体皮层破坏较严重。阿苯哒唑、甲苯咪唑对虫体皮层破坏程度低于吡喹酮,但对肌层、实质组织层破坏较吡喹酮略重。结论吡喹酮、阿苯哒唑、甲苯咪唑对微小膜壳绦虫均有明显杀虫作用,作用强度以吡喹酮最强,其次是阿苯哒唑、甲苯咪唑。     

抗人芽囊原虫药物筛选及灭滴灵对其作用机理

在体外,11种药物对人芽囊原虫作用的结果表明:人芽囊原虫对抗原虫药物灭滴灵、甲氟喹、喹碘仿敏感,对大蒜素不敏感;对抗蠕虫药物阿苯达唑、左旋咪唑、甲苯咪唑不敏感;对抗生素氯霉素和土霉素敏感,对庆大霉素和新霉素不敏感。灭滴灵作用虫体,扫描电镜观察,表面有蜂窝状凹陷及裂逢,透射电镜观察,细胞质内质网、高尔基体、细胞内膜及细胞核外膜破损,虫体细胞质出现空泡化和颗粒化。     

实验室中驱治猪、牛绦虫药物的选用

在我国古代的《神农木草经》、《千金方》、《外台秘要》等著作中都提到槟榔,狼芽可驱绦虫,并被沿用至今;近年又出现化学合成的氯硝柳胺,甲苯味唑、吡哇酮等驱绦药物。这些药物的驱虫效果好,治愈率达90％以上甚至100％。但从事寄生虫学实验研究工作的人们,当遇到绦虫病患者时,不仅注意驱虫治疗,同时也考虑到虫体的收集,以便为教学、科研提供实验材料。因此从实验室角度出发,在驱绦时应选择疗效高,副作用小,虫体受损伤小的药物,这样既能保证患者安全,又可得到完整的虫体供实验室     

苯甲酸制备新工艺研究

采用单因素实验研究了一种高锰酸钾氧化甲苯制苯甲酸的新工艺：高锰酸钾配成饱和溶液全部投入反应器。以氧化铁为催化剂，n(甲苯)：n(高锰酸钾)=1：1，分段加热反应4h(75℃加热1．5h、85℃加热1．5h、95℃加热1h)，产率可达74．32％。     

三头甲巯咪唑配体及其Ag（Ⅰ）配合物的合成

合成了一种新型三头甲巯咪唑配体2,4,6-三甲基-1,3,5-三（1-甲基咪唑-2-硫）甲苯,并通过元素分析、IR、1H和13C NMR波谱确定了化合物的结构。还利用扩散法得到了该配体的一种Ag配合物,并对配合物的结构进行了分析。     

Indoor thermal environment of wooden-plank wall dwellings in summer in Chongqing

There are a large number of wooden-plank wall dwellings, a kind of traditional house with regional characteristics, existing in Chongqing area. We chose a typical house in Chongqing as the subject and measured it during summer to research the situation of the indoor thermal comfort of wooden-plank wall dwellings. Based on the particularity of local residents’ living habit and the characteristics of the local buildings, we analyzed the data of the field measurement and evaluated the thermal environment with APMV. The results show that the indoor thermal comfort of wooden-plank wall dwellings in summer is improved mainly by natural ventilation.     

Analysis of streamwise conduction in forced convection of microchannels using fin approach

The effects induced by streamwise conduction on the thermal characteristics of forced convection for single-phase liquid flow in rectangular microchannel heat sinks under imposed constant wall temperature have been studied. By employing the fin approach in the first law of analysis, models with and without streamwise conduction term in the energy equation were developed for hydrodynamically and thermally fully-developed flow under local thermal non-equilibrium for the solid and fluid phases. These two models were solved to obtain closed form analytical solutions for the fluid and solid temperature distributions and the analysis emphasized details of the variations induced by the streamwise conduction on the fluid temperature distributions. The effects of the Peclet number, aspect ratio, and thermal conductivity ratio on the thermal characteristics of forced convection in microchannel heat sinks were analyzed and discussed. This study reveals the conditions under which the effect of streamwise conduction is significant and should not be neglected in the forced convective heat transfer analysis of microchannel heat sinks.     

Thermal comfort evaluation of people in subway station

We analyzed the characteristics of subway station environment and the change of thermal comfort for passengers when they are in and out of the station. The dynamic thermal comfort evaluation model RWI (relative warmth index) and HDR (heat deficit rate) were built on the distinguishing features of public area in subway station. Taking one representative subway station in Nanjing as the research object, the thermal comfort conditions in different seasons and different parts were studied by field tests, questionnaires and model-evaluating. The calculated RWI shows that although the thermal comfort in Nanjing metro is relatively acceptable, ideal thermal comfort has not been achieved. And it is found that associated with predicted mean vote (PMV), using RWI can evaluate the thermal comfort more precisely.     

气候特征对人体适应性影响的实验研究

通过在春夏过渡季节开展人工气候室实验,研究了季节及地域气候条件与室内人体热感觉的关系,以探讨气候特征对人体热适应性的影响.研究结果表明,在春夏过渡季节人们对室内环境的冷热耐受性不同,室外温度越高,人们的冷耐受性越弱,热耐受性越强.此外,人体热感觉还受其长期居住地区的气候特征所影响.由于人们对各自居住地区的气候特征和室内环境具有适应性,在相同的室内热环境下,来自不同地区的受试者在热感觉上有一定差异,表现为南方人较北方人有更强的冷耐受性和热耐受性.     

CPU散热器热阻智能测试系统设计

对热阻的精确测量是设计具有优良散热性能的CPU散热器的前提。本文介绍了以高精度数字温度传感器DS18B20为核心部件的CPU散热器热阻测量系统的设计方法,该系统具有测量准确、安全可靠、操作简单等特点。     

保温隔热材料在建筑工程中的应用

本较系统地介绍了目前常用的保温隔热材料的类型、性能特点及在建筑工程上的应用，包括选材、保温做法、设计计算方法及应用中应注意的问题。     

热冲压成形技术及发展前景

世界汽车工业汽车轻量化技术的可持续发展带动了热成形技术的快速发展,并成为汽车制造领域的热门技术。围绕热成形技术的特点对热冲压成形技术国内外现状进行了介绍,重点从热成形钢板开发、热成形模具设计技术、热成形工艺关键装备技术、以及热成形零件设计技术等方面详细探讨了热成形技术的技术发展,并对热成形技术的未来前景进行了分析与展望。     

Synthesis and Characterization of Modified Epoxy Resins by Silicic Acid Tetraethyl Ester and Nano-SiO2

A kind of modified epoxy resins was obtained by condensation of epoxy resin with silicic acid tetraethyl ester(TEOS) and nano-SiO2. The reactions were performed with hydrochloric acid as a catalyst at 63℃. The structure, thermal stability and morphological characteristics of the modified epoxy resins were studied through infrared spectra (FF-IR) analysis, thermogravimetric (TG) analysis and scanning electron microscopy respectively. It has been found from the IR and TG study that modified epoxy resins have greater thermal stability than epoxy resins, and its thermal stability has been improved by the formation of inter-crosslinked network structure. The modified epoxy resins exhibit heterogeneous morphology and heterogeneity increases with more TEOS feeding, which in turn confirms the formation of inter-crosslinked network structure in modified epoxy resins.     

液体混合物导热系数理想模型的建立及其应用

根据液体结构的特点,通过建立液体混合物导热系数的理想模型,发展了计算混合液体导热系数的新方法.对288种含水和非水液体混合物2 060个数据点的拟合结果表明,计算值与实验值的一致性令人满意,平均误差0.98%,计算精度优于文献方法.据此发展了一种根据纯物质导热系数预测混合液体导热系数的方法,预测结果的平均误差为1.69%,小于文献方法的误差.     

南通地区应用外墙保温技术研究

摘要：外墙保温是改善居住热环境行之有效的技术,但无论从气候条件、保温要求还是墙材的选择上,都有着显著的地域特点。文章对南通地区外墙保温常用的各种技术进行了系统分析,并在此基础上提出了相应建议,以期为南通地区工程实际应用以及其他地区的应用研究提供参考。