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1.
Working memory training improves children's cognitive performance on untrained tasks; however, little is known about the underlying neural mechanisms. This was investigated in 32 typically developing children aged 10–14 years (19 girls and 13 boys) using a randomized controlled design and multi-modal magnetic resonance imaging (Devon, UK; 2015–2016). Training improved working memory performance and increased intrinsic functional connectivity between the bilateral intraparietal sulci. Furthermore, improvements in working memory were associated with greater recruitment of the left middle frontal gyrus on a complex span task. Repeated engagement of fronto-parietal regions during training may increase their activity and functional connectivity over time, affording greater working memory performance. The plausibility of generalizable cognitive benefits from a neurobiological perspective and implications for neurodevelopmental theory are discussed.  相似文献   
2.
Abstract

Carnosine was originally discovered in skeletal muscle, where it exists in larger amounts than in other tissues. The majority of research into the physiological roles of carnosine have been conducted on skeletal muscle. Given this and the potential for muscle carnosine content to be increased with supplementation, there is now a large body of research examining the ergogenic effects (or otherwise) of carnosine. More recent research, however, points towards a potential for carnosine to exert a wider range of physiological effects in other tissues, including the brain, heart, pancreas, kidney and cancer cells. Taken together, this is suggestive of a potential for carnosine to have therapeutic benefits in health and disease, although this is by no means without complication. Herein, we will provide a review of the current literature relating to the potential therapeutic effects of carnosine in health and disease.  相似文献   
3.
The French Football Federation was the first football governing body to put in place, in 1990, a financial regulation system. It might be expected that UEFA’s Financial Fair Play (FFP) system established in 2010 would be similar to French DNCG (National Direction for Management Control) regulations. However, while FFP is concerned with profitability, DNCG is focused on solvency. Hence, a French club may be loss-making and not compliant with FFP, while at the same time being solvent in accordance with DNCG rules. Our research confirms that most French clubs do not conform to FFP rules. As such, it provides further evidence that DNCG has not prevented poor financial management within French clubs. The coexistence of DNCG and FFP– or any other domestic financial regulation and FFP –may result in disparities between domestic clubs. As a consequence, there should be consistent financial regulation in all European leagues.  相似文献   
4.
This paper reviews surveys of the use of time by academic staff between 1962 and 1994. It reports on the findings of a time diary survey in 1994 of the use of time by academic and academic-related staff at British'old'universities during working weeks in term-time and vacation. The results of the time diary survey are analysed according to respondents'sex, staff grade, type of week, age, type of work, and time when work took place. The results are compared with results of previous surveys, and trends through time are suggested. In conclusion, the paper considers the recent mass expansion of higher education, the effects of this in increasing the workload of university staff, and measures to ameliorate this situation.  相似文献   
5.
In order to determine the potential of alternative technologies in social studies education, we must understand the goals of such education, the capabilities of the technologies, and teachers’ and students’ responses to new technologies. The author suggests that the new technologies can contribute to the goals of learning about the past, learning about democratic life and institutions, and making students knowledgeable as consumers and producers of information. One major obstacle is a lack of time and money for teachers to experiment with the technologies. Stephen T. Kerr is professor of education in the College of Education at the University of Washington. His research focuses on the application of new technologies in schools and other educational environments, and particularly on the ways in which technology affects the social structure (roles and expectations, instructional patterns, organization) of those institutions. He has done work on human-computer interaction, as well as on how new communication technologies have changed the educational system of the former USSR.  相似文献   
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