| HSP47与宫腔粘连的关系及在纤维化疾病中的意义 |
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| 引用本文： | 王祥珍,;马娜娜.HSP47与宫腔粘连的关系及在纤维化疾病中的意义[J].大理师专学报,2014(4):59-62. |
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| 作者姓名： | 王祥珍 ;马娜娜 |
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| 作者单位： | [1]深圳市南山区妇幼保健院,广东深圳518052; [2]广东医学院,广东湛江524000 |
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| 摘 要： | 目的：综述HSP47在纤维化疾病中的意义,探索宫腔粘连的发病机制。方法：对HSP47在肝纤维化、肺纤维化、肾纤维化、皮肤瘢痕等纤维化疾病中的意义进行探讨,探索其与宫腔粘连的关系。结果：HSP47在纤维化疾病中高表达,与宫腔粘连的发生存在某种关系。结论：对宫腔粘连的发病机制进行探讨和展望。
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| 关 键 词： | 热休克蛋白47 宫腔粘连 转化生长因子β1 纤维化 |
The Relationship between HSP47 and Intrauterine Adhesions and Its Significance in Fibrosis Diseases |
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| Institution: | WANG Xiangzhen, MANana (1.Nanshan Maternity ＆ Child Healthcare Hospital of Shenzhen, Shenzhen, Guangdong 518052, China; 2.Guangdong Medical College, Zhanjiang, Guangdong 524000, China) |
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| Abstract: | Objective：To review the significance of HSP47 in fibrosis disease and explore the pathogenesis of intrauterine adhesions. Methods：The significance of HSP47 in fibrosis diseases such as liver fibrosis,pulmonary fibrosis,renal fibrosis and skin scar was discussed,and the relationship between HSP47 and intrauterine adhesions was explored. Results：HSP47 was high expression in fibrosis disease,and there was relationship between HSP47 and intrauterine adhesions. Conclusion：The relationship between HSP47 and intrauterine adhesion are discussed. |
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| Keywords: | HSP47 intrauterine adhesions TGF-β1 fibrosis |
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