| 腺苷酸活化蛋白激酶与运动的研究进展 |
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| 引用本文： | 潘志军.腺苷酸活化蛋白激酶与运动的研究进展[J].山东体育学院学报,2006,22(6):59-62. |
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| 作者姓名： | 潘志军 |
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| 作者单位： | 南京理工大学体育部,江苏,南京,210094 |
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| 摘 要： | 1973年,Berg和Carlson等分别报道了一个与3羟基3甲基戊二酸单酰辅酶A(3-hydr-oxy 3 methylglutaryl-CoA,HMG-CoA)还原酶和乙酰辅酶A羧化酶(acetyl-CoA carboxy-lase)相关的蛋白激酶,随后的研究表明,其活性受AMP的调节,故称为AMP活化蛋白激酶(AMP activated protein kinase,AMPK
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| 关 键 词： | 腺苷酸活化蛋白激酶 亚基 亚型 活性 运动 |
| 文章编号： | 1006-2076(2006)06-0059-04 |
| 收稿时间： | 07 12 2006 12:00AM |
| 修稿时间： | 2006年7月12日 |
Development of AMP - activated protein kinase and exercise |
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| PAN Zhi-jun.Development of AMP - activated protein kinase and exercise[J].Journal of Shandong Physical Education Institute,2006,22(6):59-62. |
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| Authors: | PAN Zhi-jun |
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| Institution: | Department of Physical Education, Nanjing University of Science and Technology, Nanjing 210094, China |
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| Abstract: | AMP-activated protein kinase(AMPK) is a sensor of energy metabolism change and plays an important regulation role in the course of energy metabolism. Some physiological stimulate can activate AMPK.Once activated,AMPK switches on catabolic processes while concomitantly switching off ATP-consuming processes. The acute exercise and chronic training improve the activity of AMPK in skeletal muscle and liver,exercise training induces adaptations response in organizeation.The mutation of AMPK has an important effect on exercise ability. |
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| Keywords: | AMP - activated protein kinase subunit isoform activity exercise |
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