合成生物学研究的工程化平台

合成生物学研究中,海量的工程化试错实验远远超出传统的劳动密集型研究范式的能力范畴,因而亟需一种变革性的工程化研究平台。工程化平台通过引进各类符合生产所需的智能装备,开展大规模个性定制模式创新,实现生命体的远程定制、异地设计、规模经济生产。工程化平台能够快速积累经验知识,是实现生命体可预测合成的科学基础。文章介绍了合成生物学研究的一些工程化平台,及其上下游机构的发展案例、创新机制与趋势。

Engineering Platforms for Synthetic Biology Research

In the field of synthetic biology research, the massive scale of trial-and-error experiments in engineering goes far beyond the traditional labor-intensive research paradigm, so it needs a transformative engineering research platform. With the introduction of various types of intelligent equipment to meet the production needs, engineering platforms carry out a large-scale of customization and research paradigm innovation, to realize the remote customization, offsite design, and economic scale production of organisms. Engineering platforms can accumulate experience and knowledge quickly, and serve as the scientific basis for the predictive synthesis of organisms. This article will introduce some cases and development trends of engineering platforms, as well as upstream and downstream institutions for synthetic biology research.