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| 急性耐力运动对大鼠脑组织一氧化氮和一氧化氮合成酶的影响及中药调节作用的研究 | |
| 引用本文： | 宋亚军,马伟,郝梅.急性耐力运动对大鼠脑组织一氧化氮和一氧化氮合成酶的影响及中药调节作用的研究[J].体育科学,2004,24(7):25-27. |
| 作者姓名： | 宋亚军 马伟 郝梅 |
| 作者单位： | 1. 山东济宁师范专科学校体育系,山东,济宁,272000 2. 山东济宁医学院基础部,山东,济宁,272000 3. 山东济宁第一人民医院检验科,山东,济宁,272000 |
| 基金项目： | 山东省教育厅科技计划项目 (NO:J0 1K5 4)，山东省高校第五批优秀中青年学术骨干资助项目部分内容 |
| 摘 要： | 采用实验法，探讨一次性长时间运动后及恢复期大鼠脑组织一氧化氮(NO)和一氧化氮合成酶(NOS)的变化以及中药对其调节性作用。研究结论：急性耐力运动后大鼠端脑iNOS活性显著性增高、cNOS显著性降低，而NO水平的过量提高可能具有神经毒性作用，这可能是急性耐力运动引发运动性中枢疲劳的重要原因；急性耐力运动后20h恢复期，大鼠端脑NO及其合成酶系的变化趋势与病理性脑损伤存在明显差异，这可能与急性耐力运动中脑组织L-精氨酸分解代谢加速和脂质过氧化水平提高有关；中药营养补充对减缓急性耐力运动中NO过量增高、保护脑组织、推迟中枢疲劳的产生具有一定的积极性作用。 |
| 关 键 词： | 一氧化氮 一氧化氮合成酶 鼠 脑组织 急性耐力运动 中药 动物实验 |
| 文章编号： | 1000-677X(2004)07-0025-03 |
Influence of Acute Endurance Exercise on NO and NOS in Brain Tissue and Regulation of Traditional Chinese Medicine in Rat |
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| SONG Ya-jun,MA Wei,HAO Mei.Influence of Acute Endurance Exercise on NO and NOS in Brain Tissue and Regulation of Traditional Chinese Medicine in Rat[J].China Sport Science,2004,24(7):25-27. | |
| Authors: | SONG Ya-jun MA Wei HAO Mei |
| Institution: | SONG Ya-jun1,MA Wei2,HAO Mei31.Department of Physical Education,Jining Teachers' College,Jining 272000,China,2.Department of Foundation Medition Jining Medical College,Jining 272000,China,3.Department of Inspection Medician,Jining First Hospital,Jining 272000,China. |
| Abstract: | By using the method of experiment,this paper discusses the change of NO and NOS in brain tissue and regulation of traditional Chinese medicine after prolong exercise and recovery period in rat.The result shows that the iNOS activity of brain gets significant increase after acute endurance exercise,while cNOS significant decreases.The excessive increasing of NO level may have neural toxicity function.It may be the main reason to cause the nerve center fatigue.Twenty hours recovery after acute endurance exercise,NO of brain end in rat and format enzyme variation tendency has significant different with pathology brain damage.Traditional Chinese medicine nutrition supplement has some positive function in reducing pressure,protecting brain tissue,prolonging nerve center fatigue. |
| Keywords: | oxidize nitrogen oxidize nitrogen format enzymes rat brain tissue acute endurance exercise Chinese medicine |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |