| 胶原调控矿化自组装机制研究 |
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| 引用本文： | 杨春蓉.胶原调控矿化自组装机制研究[J].福建工程学院学报,2010,8(1). |
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| 作者姓名： | 杨春蓉 |
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| 作者单位： | 福建工程学院,材料科学与工程系,福建,福州,350108 |
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| 基金项目： | 福建省教育厅科技计划项目(JK2009021);;福建工程学院科研启动基金项目(GY-Z0854) |
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| 摘 要： | 通过模拟体液的特征配制特殊生理溶液,并以此生理溶液和胶原基质为矿化系统,观察和分析胶原基质在体外的矿化;结果发现:胶原在体外仿生矿化生成的矿物相为具有规则叶片状结构、低结晶度的碳酸羟基磷灰石;表明了羟基磷灰石矿物晶体在胶原的反应成核位点通过化学键合作用进行自组装,这种自组装结构受胶原大分子与羟基磷灰石晶体之间的相互反应以及胶原分子的自组装能力诱导。
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| 关 键 词： | 胶原 矿化 自组装 |
Study of collagen self-assembly mechanism of regulating mineralization |
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| Yang Chunrong.Study of collagen self-assembly mechanism of regulating mineralization[J].Journal of Fujian University of Technology,2010,8(1). |
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| Authors: | Yang Chunrong |
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| Institution: | Materials Science and Engineering Department/a>;Fujian University of Technology/a>;Fuzhou 350108/a>;China |
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| Abstract: | A special physiological solution combined with collagen matrix was used as a mineralization system to study collagen self-assembly mechanism of regulating mineralization.The physiological solution was prepared through simulating the characteristics of body fluid.The mineralized process and mechanism of collagen matrix in vitro was observed and analyzed.The generated product in mineralized collagen was regular leaf-shaped hydroxyapatite with low crystallinity.The hydroxyapatite was characterized by strong ch... |
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| Keywords: | collagen mineralization self-assembly |
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