有氧运动对成年男子股四头肌能量代谢影响的磁共振磷谱研究

目的:用核磁共振磷谱分析方法研究有氧训练对股四头肌能量代谢的影响。方法:受试者进行有氧运动训练,运动强度为最大摄氧量的70%,每周五次。运动时间为45min。训练过程共持续10周。在Philips公司生产的1.5T磁共振成像系统上对受试者训练前后进行31P-MRS采集及定量分析。结果:31P-MRS可检测到七个不同代谢物质的共振峰,训练后与训练前相比,PCR浓度显著性升高。从动态磷谱上可以观察到,训练前与训练后相比,PME和PDE化合物浓度无明显变化,γ-ATP、a-ATP和β-ATP化合物浓度基本保持恒定。定量负荷运动后Pi化合物浓度明显升高,通过恢复,Pi逐渐下降;3min24s训练前与训练后相比有显著性差异。PCR化合物浓度明显下降,通过恢复,PCR逐渐升高。结论:经过十周有氧训练,安静状态下训练后与训练前PCR浓度相比,显著性升高。短期有氧训练能提高组织能量代谢状态。31P-MRS是检测训练效果的有效工具。经过十周有氧训练,定量负荷运动后3min24s训练前与训练后Pi、PCR浓度相比,有显著性差异。训练后恢复较快。短期有氧训练能提高Pi、PCR恢复速率。31P-MRS可以作为无创性评价代谢物恢复率的有效方法。

Research on Phosphorus Magnetic Resonance Spectroscopy of Aerobic Exercise to Healthy Human Skeletal Muscle

Objective： To evaluate skeletal muscle function using in vivo dynamic Phosphorus MagneticResonance Spectroscopy（31P - MRS）. Methods ： Subjects performed aerobic exercise training, the Exer-cise intensity is 70% of the Maximal oxygen uptake. 45 minutes a time, five times a week for 10 consecu-tive weeks. Philips produced in the core of the system is equipped with multiple （MNS） Gyroscan Intera1.5T MRI system, to be used to analyse the test 31P - MRS of the subjects before and after training. Re-sults ： The characteristics of 31P - MRS under the state quiet ： there are seven different Formant of Metabo-lites in the 31P - MRS in the quadriceps of the Subjects. After ten weeks of aerobic training, under quietstate PCR levels compared with after training and before training were significantly increased. The charac-teristics of 31P- MRS after the quantitative load exercise：We can see from the dynamic phosphorus spec-trum between the before training and after training ： the compounds of PME and PDE doesn＇ t change signif-icantly ,γ-ATP,a -ATP β-ATPRemained constant. The concentration of compound Pi increase sig-nificantly, but after the rest, Pi decreased gradually. The Concentration of compound PCR decrease signif-icantly, but after the rest, PCR increase gradually, the concentration of Pi, PCR of 3min24s after trainingand before training has significant difference. Conclusion：After ten weeks of aerobic training, under quietstate PCR levels compared with before training and after training, were significantly increased. Prove short- term aerobic training can improve the state of energy metabolism. 31P - MRS is an effective tool for de-tecting training effectsAfter ten weeks of aerobic training and quantitative load exercise, the concentrationof Pi, PCR of 3min24s after training and before training has significant difference. The after training recov-ered rapidly. Proved short -term aerobic training can improve the PI, PCR recovery rate. 31P -MRS canbe used as a effective way of noninvasive eval