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Ursolic acid inhibits proliferation and induces apoptosis of HT-29 colon cancer cells by inhibiting the EGFR/MAPK pathway |
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| Authors: | Jian-zhen Shan Yan-yan Xuan Shu Zheng Qi Dong Su-zhan Zhang |
| Institution: | (1) Department of Biological Chemistry, Medical School, University of Athens, 75 Mikras Asias Street, 115 27 Goudi, Athens, Greece;(2) Laboratory of Cell Proliferation and Ageing, Institute of Biology, NCSR Demokritos, 153 10 Athens, Greece;(3) Laboratory of Pharmacognosy, Department of Pharmacy, University of Athens, Panepistimiopolis, 157 71 Zografou-Athens, Greece;(4) Laboratory of Pathophysiology, Medical School, University of Athens, 75 M.Asias, 115 27 Athens, Greece; |
| Abstract: | rectal cancer. |
| Keywords: | Colon cancer Ursolic acid Epidermal growth factor receptor (EGFR) Mitogen-activated protein kinase (MAPK) Apoptosis |
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