孕妇羊水AFP的检测价值分析

目的：探讨孕妇年龄因素对孕中期（16周）羊水甲胎蛋白（AFP）浓度的影响。方法：采用电化学发光法，测定2005．1～12月来我院检查的怀孕16周孕妇羊水AFP浓度，将测定值按孕妇年龄分组（01组、02组、G3组）进行比较分析。结果：羊水AFP浓度随孕妇年龄增大而升高（P〈0．05），且4例确诊胎儿神经管缺陷孕妇年龄均大于30岁。结论：孕中期（16周）孕妇羊水AFP浓度受年龄因素影响，高龄孕妇羊水AFP浓度明显高于适龄孕妇。提示：高龄孕妇应做羊水AFP筛查检测，有助于提高神经管缺陷患儿的诊出率，避免患儿出生。

Analysis on the AFP Density in Amniotic Fluid of the Pregnant Women

Objective: To study the influence of the pregnant woman's age on the AFP in amniotic fluid during the 16th GW.Methods: The AFP in amniotic fluid was checked with ECLIA mothod for pregnant wowen in 2005,and all the abtained data were divided into three groups(in turn G1 group,G2 group,G3 group)according to the pregnant wowan's age.Results: The AFP density of the older group was higher than that of the younger group(P<0.05),four gregnant women who were diagnosed of nerve tube blemish were all over 30 years.Conclusion: The AFP density in amniotic fluid during the 16th GW will be influenced with the increasing of prenant woman's age,the AFP density of the older group was higher than that of the younger group.Hint: For the older pregnant woman,the AFP in amniotic fluid should be checked as a rule.The check rate of nerve tube blemish can be increased,and the birth of ill infant can be avoided.