| Mg2+对超速驱动后离体大鼠心脏的保护作用 |
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| 引用本文： | 李岩,颜辉.Mg2+对超速驱动后离体大鼠心脏的保护作用[J].体育学刊,2004,11(4):49-51. |
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| 作者姓名： | 李岩 颜辉 |
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| 作者单位： | 烟台师范学院,体育学院,山东,烟台,264025 |
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| 摘 要： | 为研究Mg^2 对疲劳心脏的保护作用，以离体大鼠心脏为研究对象，采用Langendorff灌流装置对超速驱动的离体心脏施加不同浓度Mg^2 的灌流液。结果表明，一定浓度的Mg^2 溶液对离体心脏具有明显的保护作用，表现为心肌乳酸脱氢酶漏出减少，谷胱甘肽过氧化物酶活性增高，丙二醛含量降低，心肌组织和线粒体钙超载减轻。
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| 关 键 词： | 镁离子 超速驱动 离体大鼠心脏 |
| 文章编号： | 1006-7116(2004)04-0049-03 |
| 修稿时间： | 2004年1月19日 |
Research on the protective function of Mg2+ to the isolated rat heart after overdriving |
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| LI Yan,YAN Hui.Research on the protective function of Mg2+ to the isolated rat heart after overdriving[J].Journal of Physical Education,2004,11(4):49-51. |
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| Authors: | LI Yan YAN Hui |
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| Abstract: | Taking isolated rat hearts as research objective,with the adoption of Langendorff perfusion device,Mg~(2+) perfusion solution of varied concentration is exerted on the overdriven isolated hearts for the research of the protective function of Mg~(2+) towards fatigue hearts. The results indicate that Mg~(2+) solution of certain concentration possesses tangible protective effect on isolated hearts with performances of the decrease of the transudation of myocardium LDH,the increase of the activity of GSH-PX,the decrease of the content of MDA and the alleviation of the calcium overloading in myocardium and mitochondrion. |
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| Keywords: | Mg~(2+) overdriving isolated rat heart |
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