猪体细胞核移植研究进展

由于猪的器官极可能成为人类未来器官的供应源，猪体细胞核移植及 转基因等方面的研究已成为全球的热点。近几年来，猪体细胞核移植研究取得了一定的进展，但总体看来核移植效率还很低（<1%），还需要不断完善核移植程序及对一些基础问题的 深入研究。本文对猪体细胞核移植研究进展及面临的一些问题作一综述与分析，旨在为研究 者提供一些有益的启示。

RECENT PROGRESS OF SOMATIC CELL NUCLEAR TRANSFER IN PIGS

Research in the field of somatic cell nuclear transfer (SCNT) and transgenic cloning in pigs has been become global hotspot, because porcine organs probably become the first source of donor organs for human xenotransplantation. Recently, great progress had been made in porcine SCNT. However, the efficiency of nuclear transfer remains very low ( < 1 % ) . It is necessary to improve the procedure of nuclear transfer and to further investigate some basic problems. Recent progress of SCNT in pigs and some existing problems are reviewed and analysed. The aim is to offer some beneficial illumination for researchers.