| 几丁质·几丁聚糖对运动小鼠心肌组织自由基代谢及血清酶活性的影响 |
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| 引用本文： | 石磊,熊正英,鱼得海.几丁质·几丁聚糖对运动小鼠心肌组织自由基代谢及血清酶活性的影响[J].西安体育学院学报,2003,20(4):61-63. |
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| 作者姓名： | 石磊 熊正英 鱼得海 |
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| 作者单位： | 1. 西安交通大学,体育部,陕西,西安,710049
2. 陕西师范大学,运动生物学研究所,西安,710062 |
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| 摘 要： | 通过建立灌服几丁质·几丁聚糖小鼠的力竭游泳训练实验模型,测定了小鼠心肌组织的超氧化物歧化酶(SOD)的活性、丙二醛(MDA)的水平以及血清谷草转氨酶(GOT)的活性。实验结果显示,灌服几丁质·几丁聚糖后,小鼠游泳运动力能明显提高;心肌组织SOD活性显著高于各自对照组;MDA含量显著低于各自对照组。说明几丁质·几丁聚糖具有较强的抗自由基损伤和抗脂质过氧化损伤的作用,服用几丁质·几丁聚糖可减轻运动所产生的内源性自由基对小鼠的伤害。另外,几丁质·几丁聚糖对小鼠心肌细胞膜有保护作用,可减少组织酶的外泄。
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| 关 键 词： | 小鼠 几丁质·几丁聚糖 自由基 超氧化物歧化酶 丙二醛 谷草转氨酶 |
| 文章编号： | 1001-747X(2003)04-0061-03 |
| 修稿时间： | 2002年9月25日 |
Effect of Chitin on Free Radical Metabolism and Serum Enzyme in Rats Myocardium |
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| Abstract: | By setting up the exhaustive swimming rats model, the activity of myocardium SOD, the quantity of MDA and the serum GOT are all valued. The results indicates that after the rats took chitin, their physical ability improved remarkably; the activity of myocardium SOD appeared superior to the control group; the quantity of MDA turned lower than the control group, which shows that chitin enjoys much stronger influence on the anti-oxidation and anti-free-radical. Besides, their ability of counteracting the free radical of myocardium jumped to a high level. Furthermore, chitin can also been used to protect the integrality of myocardium cell membrane; to reduce the escape of enzyme from the cell. |
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| Keywords: | rats chitin free radical superoxide dismutase(SOD) malordialdehyde(MDA) glutamic-oxalacetic transaminase(GOT) |
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