Changes in serum lipids in normal and diabetic guinea pigs on feeding Phaseolus aureus (Green gram) |
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Authors: | Anurag Srivastava L D Joshi S P Singh |
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Institution: | 1. Department of Biochemistry, M.L.B. Medical College, 284 128, Jhansi, U.P., India
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Abstract: | Normal and alloxan induced diabetic guinea pigs were kept on whole seed diet of green gram for 4 weeks. Serum total lipids
were found to be significantly decreased in both normal and diabetic guinea pigs (P <0.001)—Both free and esterified fractions
of cholesterol were found to be lowered significantly in diabetic animals (P<0.05; <0.01, respectively), whereas only esterified
fraction was reduced significantly in case of normals (P<0.05). Significant lowering of triglyceride levels (P<0.01) was also
noticed in both normal as well as diabetic guinea pigs while phospholipids remained almost unaffected. Green gram feeding
decreased the total cholesterol / phospholipid ratio from 0.630 to 0.625 in normal and from 1.039 to 0.850 in diabetic guinea
pigs indicating its antiatherogenic nature. |
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Keywords: | |
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