不同负荷的运动训练对大鼠血浆ADM、ET含量变化的影响及意义

为了探讨不同负荷运动训练对机体心血管系统内分泌功能的影响,以大鼠为运动模型进行为期8周不同负荷的运动训练,测定其血浆肾上腺髓质素(ADM)、内皮素(ET)含量.结果表明:1)长期中等负荷的运动训练后血浆ET、ADM含量增加且呈正相关;2)长期大负荷的运动训练会导致机体血浆ET含量显著增高,ADM含量显著下降.结论:长期中等负荷的运动训练可促进ET、ADM分泌适度增加,对机体产生有益的影响;长期大负荷运动训练可导致两种血管活性肽的分泌失衡,对健康不利.

Research on Impacts of Different Loaded Exercise Training on Changes of the Content of the Plasma ADM, ET in Rats and its Significance

In order to explore impacts of different loaded exercise training on the endocrine function of circulatory system in rats. The content of the plasma Adrenomedullin (ADM), endothelin(ET) in rats were measured after 8-week swimming training with the different loaded exercises. Several results can be concluded as the followings: 1) the content of plasma ET, ADM was properly increased by the long-time middle-intensity training;2) The content of plasma ET was obviously increased,and the content of ADM was markedly decreased by the long-time high-intensity training. In conclusion, the long-time middle-intensity sports training can improve the excretion of ET and ADM;the long-time high-intensity sports training can lead to the turbulence of vessel active peptide, which is harmful to health.