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差异蛋白质组学在运动人体科学中的应用展望
引用本文:刘田,史绍蓉.差异蛋白质组学在运动人体科学中的应用展望[J].首都体育学院学报,2006,18(2):117-120.
作者姓名:刘田  史绍蓉
作者单位:湖南师范大学体育学院,湖南,长沙,410012
摘    要:差异蛋白质组学是现阶段蛋白质组学研究的一个主要内容。它着重于寻找和筛选由任何有意义的因素引起的2个样本之间的差异蛋白质图谱,以揭示细胞生理和病理状态的进程和本质,细胞对外界环境刺激反应的途径,以及细胞调控机制,同时获得对某些关键蛋白质的定性和功能分析。它对于寻找有意义的生物标志物和确定信号转导通路具有重要的实际意义。本文阐述了差异蛋白质组学的概念、研究内容、研究技术及其研究进展,并着重论述了其在运动人体科学专业研究中的应用前景。

关 键 词:差异蛋白质组学  研究技术  运动人体科学  应用
文章编号:1009-783X(2006)02-0117-04
收稿时间:2005-12-06
修稿时间:2005年12月6日

The Prospect of the Application of Differential Proteomics in Kinesiology
LIU Tian,SHI Shao-rong.The Prospect of the Application of Differential Proteomics in Kinesiology[J].Journal of Capital College of Physical Education,2006,18(2):117-120.
Authors:LIU Tian  SHI Shao-rong
Institution:School of Physical Education, Hunan Normal University,Changsha 410012 ,China.
Abstract:Differential proteomics is a major research area in proteomics area at present,which is mainly aimed at detecting and confirming the different proteins caused by special meaningful stimulation between two groups of samples.By analysis of the difference between samples,the progress and nature of the physiological and pathological state of cells,their way of response to the external world's stimulation and their mechanism of adjustment can be revealed,while the determination and functional analysis of some key proteins can be obtained.It is of practical significance for seeking meaningful biological symbols and determining the access of signals transferred.This article has described the concept,research contents,techniques and progress of differential proteomics,and discussed its prospect of application in the area of kinesiology.
Keywords:Differential proteomics  Research techniques  Kinesiology  Application
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