不同负荷游泳运动对雄性老龄小鼠骨代谢状况影响的研究

为探讨不同负荷游泳运动对老年男性骨质疏松的预防作用,以12月龄雄性小鼠(老龄雄性小鼠)为研究对象,随机分为5组:30分组;60分组;60分+负重组(负重2.5%体重);实验对照组;安静对照组.运动组的运动方式为游泳,共训练8周,观察增龄和不同负荷游泳运动对老龄雄性小鼠腰椎骨、股骨骨矿含量、血清性激素(睾酮T和雌二醇E2)水平的影响.研究结果表明,适宜负荷的游泳运动可使老龄雄性小鼠骨矿含量和血清性激素水平显著增加,减缓其伴随增龄而发生的骨丢失和性激素水平下降;而且适宜负荷的较大负荷的游泳运动对改善老龄雄性小鼠的骨矿含量、性激素水平更有益.该结果提示,游泳是一种适合于老年男性的健身方式,适宜负荷的游泳运动可起到预防老年男性骨丢失、骨质疏松的作用;此外,老年男性在进行游泳锻炼时,在锻炼者能够承受的情况下尽量选择适宜于个体自身的较大运动负荷将会使其受益更大.

Effects of Swimming with Different Workload on Bone Metabolism in Aged Male Mice

In order to probe into effects of swimming with different workload on the prevention of osteoporosis in aged men, the male mice of 12 months old (the senile male mice) were used as the subjects of the study and were randomly divided into 5 groups - the 30min. group, the 60min. group, the 60min. with weight group (weight of 2.5% of the body weight), the experimental control group and the sedentary control group. The exercise group had their swimming training for 8 weeks. Effects of aging and swimming with different workload on the mineral content of the lumbar bone and the thighbone as well as the serum hormone level - testosterone (T) and estradiol (E2) were observed. The results indicated that swimming with proper workload remarkably increased the bone mineral content and the serum hormone level of the aged male mice as well as delayed the decrease of bone loss with aging and the sex hormone level. Furthermore, swimming with larger workload (within the proper workload) was beneficial to the improvement of the bone mineral content and the sex hormone level of the aged male mice, which shows that swimming is a good method for body-building, suitable for old men. Proper workload of swimming plays a role of preventing the old men from bone loss and osteoporosis. In addition, it is important for the old men to choose swimming with greater workload suitable for themselves so long as they can endure.