| 运动频率和递增强度运动对大鼠海马神经发生的影响 |
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| 引用本文： | 娄淑杰,刁玮,陈佩杰.运动频率和递增强度运动对大鼠海马神经发生的影响[J].体育科学,2010,30(1). |
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| 作者姓名： | 娄淑杰 刁玮 陈佩杰 |
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| 作者单位： | 上海体育学院运动科学学院,上海,200438 |
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| 基金项目： | 国家自然科学基金资助项目，上海市重点学科建设项目 |
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| 摘 要： | 目的:探讨运动频次和隔周递增强度运动对大鼠海马神经发生的影响.方法:将60只雄性5周龄SD大鼠随机分为安静对照(C)组、每天运动(E0)组、隔1日运动(E1)组、隔3日运动(E3)组、隔周运动(E7)组和隔周递增强度运动(E7I)组.运动方式为跑台运动.腹腔注射BrdU于各组大鼠,持续注射6天.采用免疫组织荧光染色技术,检测各组大鼠海马齿状回内新生细胞和新生神经元数量.结果:各组动物海马齿状回内BrdU免疫阳性(Br-dU+)细胞数目为:C组37.62±9.02,E0组46.01±10.82,E1组49. 06±12. 07,E3组41. 20±11. 02,E7组37.23±16. 45,E71组53. 97±10. 67.各组大鼠海马齿状回内BrdU和NeuN免疫双阳性(BrdU++NeuN+)细胞微分别为:C组15.26±4.42;E0组17. 61±3. 86,E1组21. 93±5.60,E3组16. 28±5.37,E7组15. 80±7.50,E7I组24. 9±土5.44.结论:在间隔不同时问的小强度运动中,隔日小强度运动最有利于大鼠海马齿状回神经发生;隔周递增运动强度也有利于大鼠海马齿状回神经发生,
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| 关 键 词： | 神经发生 海马 鼠 动物实验 |
Effect of Exercise Frequency and Increasing Intensity Exercise on Hippocampal Neurogenesis in Rats |
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| LOU Shu-jie,DIAO Wei,CHEN Pei-jie.Effect of Exercise Frequency and Increasing Intensity Exercise on Hippocampal Neurogenesis in Rats[J].China Sport Science,2010,30(1). |
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| Authors: | LOU Shu-jie DIAO Wei CHEN Pei-jie |
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| Institution: | LOU Shu-jie,DIAO Wei,CHEN Pei-jieShanghai University of Sport,Shanghai 200438,China |
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| Abstract: | Objective:To investigate effects of movement frequency and incremental exercise intensity on hippocampal neurogenesis in rats.Methods:Sixty male SD rats of 5-week-old were randomly divided into 6 groups:The sedentary control(C)group,the everyday exercise(E0)group,the every other day exercise(E1)group,the every three days exercise(E3)group,the every other week exercise(E7)group and the every other week increasing intensity exercise(E7I)group.All rats except C group were forced to run on treadmill.Immunofluor... |
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| Keywords: | BrdU NeuN |
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