Simulation of 3D needle-tissue interaction with application to image guided prostate brachytherapy |
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Authors: | JIANG Shan HATA Nobuhiko XIAO Bohan AN Weijin |
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Institution: | 1. School of Mechanical Engineering, Tianjin University, Tianjin 300072, China;Tianjin Key Laboratory of Advanced Manufacturing Technologies and Equipments, Tianjin 300072, China;Department of Radiology, Brigham and Women's Hospital and Harvard Medical School,75 Francis Street Boston, MA 02115, USA 2. Department of Radiology, Brigham and Women's Hospital and Harvard Medical School,75 Francis Street Boston, MA 02115, USA 3. Department of Radiology, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China 4. School of Mechanical Engineering, Tianjin University, Tianjin 300072, China;Tianjin Key Laboratory of Advanced Manufacturing Technologies and Equipments, Tianjin 300072, China |
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Abstract: | To improve global control of disease and reduce global toxicity, a complex seed distribution pattern should be achieved with great accuracy during brachytherapy.However, the interaction between the needle and prostate will cause large deformation of soft tissue.As a result, seeds will be misplaced, sharp demarcation between irradiated volume and healthy structures is unavailable and this will cause side effects such as impotence and urinary incontinence.In this paper, a 3D nonlinear dynamic finite element s... |
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Keywords: | brachytherapy soft tissue finite element method dynamic simulation |
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