| 高血压大鼠与正常大鼠左室流出道动作电位的分析 |
| |
| 引用本文： | 焦宏,邱丽颖,吕莉,马建伟.高血压大鼠与正常大鼠左室流出道动作电位的分析[J].河北北方学院学报(医学版),2001(1). |
| |
| 作者姓名： | 焦宏 邱丽颖 吕莉 马建伟 |
| |
| 作者单位： | 张家口医学院生理教研室 075000
(焦宏，邱丽颖，吕莉)，张家口医学院生理教研室 075000(马建伟) |
| |
| 摘 要： | 目的:为了研究高血压大鼠左室流出道电位的变化。方法:利用大鼠的离体心脏,采用常规玻璃微电极细胞内记录方法。观察静息电位(RP)、0相去极幅度(APA)、0相最大除极速度(Vmax)、复极时程(APD)以及复极50％(APD_(50))和复极90％(APD_(90))的时间。结果:高血压大鼠左室流出道诱发电位APD、APD_(50)、APD_(90)都明显高于正常同龄大鼠(P<0.01)。结论:高血压大鼠左室流出道动作电位复极时程延长。
|
| 关 键 词： | 自发高血压大鼠 动作电位 左室流出道 |
Analysis of induced action potential of SHR and Wistar rat on left ventricular outflow tract |
| |
| Jiao Hong,Qiu Liying,LV Li,Ma Jianwei.Analysis of induced action potential of SHR and Wistar rat on left ventricular outflow tract[J].Journal of Hebei North University:Medical Edition,2001(1). |
| |
| Authors: | Jiao Hong Qiu Liying LV Li Ma Jianwei |
| |
| Institution: | Jiao Hong,Qiu Liying,LV Li,Ma Jianwei Department of Physiology,Zhangjiakou Medical College,075000 |
| |
| Abstract: | Objective: To imestigate the changes of action potential in SHR left ventricular outflow tract. Methods: isolated heart and intracelluar record were usedfor electrophysiological parameters examining Resting potential (RP), amplitude of action potential( APA), maximal rat of depolarization of phase 0 (Vmax), duration of 50% and 90% repolarization (APDso and APD90) changes were studied. Results: The resucts showed that APD, APD50 and APD90 of SHR were all longer than that of control group, and The differences was statistically significant (P<0.01). Conclusion: APD of SHR were prolonged, compared sith normal wistarrat |
| |
| Keywords: | Spontaneous hypertensive rat Action potential Left ventricular outflow tract |
| 本文献已被 CNKI 等数据库收录！ |
|
