A clinical study on cortisol and certain metabolites in some chronic psychosomatic disorders

Present clinical study involved two groups of psychosomatic disorders, bronchial asthma and rheumatoid arthritis. In the study, the levels of plasma cortisol, blood glucose, total cholesterol and triglycerides were estimated in 125 clinical subjects, (50 normal controls, and 40 having bronchial asthma and 35 suffering from rheumatoid arthritis. The results showed a significant change in the levels of plasma cortisol and blood glucose in both the stressed clinical groups' vis-à-vis normal controls. The levels of atherogenic lipids (total cholesterol and triglycerides) were found quite elevated in both the diseased groups. However, in rheumatoid arthritis, the physiological changes were relatively more pronounced. The findings of this study indicate that rheumatoid arthritis is a relatively more chronic and late onset disorder as the functional performance of hypothalamopituitary-adrenocortical axis gradually declines with passage of time and the ability of the adrenocortical response to return to normalcy becomes impaired.     

Serum cortisol,immunoglobulins and some complements among depressed patients

Psychiatric disorders especially depression are associated with a variety of changes in immunity parameters. In this work, an attempt was carried out to make estimation about the correlation between immunity and depression through the measuring of IgG, IgA, and IgM and complements (C3 and C4) levels in the serum of patients and comparing them with the corresponding levels of healthy control group. The results showed a significant increase in serum level of C3, C4, cortisol, IgG and no significant differences were noticed in the level of IgA and IgM in the depressed patients group as compared with control group. A slight positive correlation was observed between cortisol versus IgG in depressed patients that is not found in normal subjects. Thus in depression, human body defenses psychologically and sometimes this defense transformed into immunological resistance that is expressed as different measurable changes in immunological parameters.     

若干西方国家评估规范的特点与模式

对北美、欧洲及大洋洲等一些国家评估协会以及欧盟委员会、OECD组织的评估规范进行了系统综述,介绍了各国评估规范的发展历史、制定过程,及其相互之间的关系,并且进行了对比分析。最后,归纳了这些国家评估规范的不同特点与三种基本模式。     

广西某低品位难选氧化锰矿选矿试验研究

根据广西某低品位氧化锰矿石原矿性质特点,试验采用两矿法酸浸及强磁选方案比较。酸浸试验显示锰浸出率高达94.89%;强磁选获得的试验指标：锰品位22.11%、MnO2品位28.01%、锰回收率70.40%。     

A microfluidic device to study cancer metastasis under chronic and intermittent hypoxia

Metastatic cancer cells must traverse a microenvironment ranging from extremely hypoxic, within the tumor, to highly oxygenated, within the host''s vasculature. Tumor hypoxia can be further characterized by regions of both chronic and intermittent hypoxia. We present the design and characterization of a microfluidic device that can simultaneously mimic the oxygenation conditions observed within the tumor and model the cell migration and intravasation processes. This device can generate spatial oxygen gradients of chronic hypoxia and produce dynamically changing hypoxic microenvironments in long-term culture of cancer cells.     

Hypoglycaemic study of some umbelliferae seeds in albino rats

Blood glucose levels were determined in normal, glucose loaded (hyperglycaemic) and diabetic rats after oral administration of some of the Caraway species and allied seeds (Cuminum Cyminum, Carum bulbocastanum, Carum Carvi, Trachyspermum ammi, and Cuminum nigrum). The data showed that the aqueous suspension of Carum Carvi seeds caused a significant reduction in blood glucose level in normoglycaemic, hyperglycaemic as well as alloxanated diabetic rats. The, drug however, did not show any blood glucose lowering effect in streptozotocin treated rats. It is suggested that C. Carvi, seeds have some hypoglycaemic principle.     

Effects of chronic ethanol consumption in blood: A time dependent study on rat

Alcohol consumption and health outcomes are complex and multidimensional. Ethanol (1.6g / kg body weight/ day) exposure initially affects liver function followed by renal function of 16–18 week-old male albino rats of Wistar strain weighing 200–220 g. Chronic ethanol ingestion increased in thiobarbituric acid reactive substances level and glutathione s-transferase activity; while decreased reduced gluatathione content and activities of catalase, glutathione peroxidase and glutathione reductase in a time dependent manner in the hemolysate. Though superoxide dismutase activity increased initially might be due to adaptive response, but decreased later. Elevation of serum nitrite level and transforming growth factor-b₁ activity indicated that long-term ethanol consumption may cause hepatic fibrosis and can elicit pro-angiogenic factors. However, no alteration in vascular endothelial growth factor-C activity indicated that ethanol consumption is not associated with lymphangiogenesis. Therefore, we conclude that long-term ethanol-induced toxicity is linked to an oxidative stress, which may aggravate to fibrosis and elevate pro-angiogenic factors, but not associated with lymphangiogenesis.     

某型警戒引导雷达典型故障检修与思考

针对某型警戒雷达在日常工作中出现的两起典型故障,通过对其系统设备的结构、性能、标准、参数、运行规律等进行细致对比,采用系统分析法分析了可能的故障原因和故障位置,再用隔离法、先易后难、逐级检修,完成了故障检修,在此基础上针对影响雷达工作状态的两种因素,给出了装备防御性维护的具体措施。     

Prostaglandin,cortisol and catecholamines in angina pectoris

Plasma prostaglandin E₂ (PGE₂)-like activity, cortisol and catecholamines were estimated in twenty stable angina pectoris and thirty control cases. PGE₂ like activity was significantly decreased (0.7 ng/ml ± 0.44) in angina patients compared to control (1.6 ng/ml ± 0.7). The plasma catecholamines were only marginally elevated in angina patients (242.8 ng/100 ml ± 14.2) compared to healthy individuals (236.2 ng/100 ml ± 5.5). The changes in plasma cortisol levels were not significant in angina (18.4 μg%± 6.5) in comparison to control (16.9 μg% ± 3.2).     

A self-phase modulated oscillator and some implications

A self-phase modulated sinewave oscillator is proved to perform as a periodic function generator. The system is investigated comprehensively and is shown to be capable of generating a variety of non-sinusoidal waveforms. The change from the generation of one waveform to the generation of another is attained by the variation of a relatively simple function in a skeletal model which does not change.     

产业生态化理论综述及若干思辨

产业生态化是我国实施可持续发展战略的重要途径,也是我国生态文明建设的重要内容。现有文献有关产业生态化的理论综述,多是从产业生态化理论产生、演变的历史角度来研究的,缺乏对产业生态化理论本身主要内容的归纳总结。基于此,本研究将有关产业生态化的研究进行归纳总结,清晰地呈现出当前产业生态化研究的主要内容,并针对各界对产业生态化理论的质疑提出若干思辨,最后指出产业生态化理论与实践进一步发展的方向与重点。     

湖北省内的部分国家重点实验室与同类实验室的比较研究

国家重点实验室是国家为提高基础研究水平,提升国家的创新能力和科技竞争力而采取的通过投资建设及直接和间接管理的国家级科学研究基地。本文将湖北省内部分国家重点实验室与国内其他实验室进行分学科领域的比较,为湖北省充分发挥国家重点实验室的作用、形成知识创新高地,从而有力促进科技创新体系的构建和原始创新能力的提升提供了现实依据。