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Subcutaneous administration of monosodium glutamate (MSG), to normal adult male mice, for six consecutive days at dose levels
of 4 and 8 mg/g body weight, significantly increased the level of free radical initiating enzyme, xanthine oxidase, whereas
the activity of free radical scavenging enzymes, like catalase and superoxide dismutase was significantly decreased in hepatic
tissue. These observations suggested that ingestion of MSG at dose level of 4 mg/g body weight and above, induced oxidative
stress in the hepatic tissue of adult male mice. 相似文献