共查询到18条相似文献,搜索用时 46 毫秒
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非酒精性脂肪性肝病(non-alcoholic fatty liver disease,NAFLD)是临床常见的肝脏疾病.特别是随着生活水平的提高,我国NAFLD发病率持续升高.因其疾病谱中非酒精性脂肪性肝炎(non-alcoholic steatohepatitis,NASH)可进展为肝纤维化、肝硬化、肝癌,严重威胁... 相似文献
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非酒精性脂肪性肝病(nonalcoholic fatty liver disease,NAFLD)是除外酒精和其他明确的损肝因素所致的,以弥漫性肝细胞大泡性脂肪变为主要特征的临床病理综合征。据调查研究,NAFLD是我国最常见的慢性肝病之一,其患病率不断上升,越来越多研究显示,NAFLD的演变发展潜在较多的危害性,早期发现,及时进行干预治疗,对减少肝纤维化、肝硬化甚或肝癌的发病率有重要意义。目前,西医对于非酒精性脂肪肝治疗缺乏有效安全药物,而中医药方面许多专家学者通过大量研究发现,祛湿活血方对于治疗非酒精性脂肪性肝病体现出显著的优势。中医治疗该病一直是业内研究热点,现将近年来祛湿活血方治疗非酒精性脂肪性肝病的研究近况进行综述,进而为该病的临床治疗提供新的思路。 相似文献
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2型糖尿病合并非酒精性脂肪肝是一种常见病,但其病因病机复杂且临床上难以治愈。近年来,其发病率持续增长且目前西医对该病的治疗尚未有十分确切的方法。中医药治疗该病具有疗效稳定、安全无毒、价格低廉、作用多靶点等优势。文章对近三年来中医治疗2型糖尿病合并非酒精性脂肪肝的相关文献的病因病机和辨证论治、传统中医疗法等方面的研究进行提炼总结,为进一步完善、规范及推广2型糖尿病合并非酒精性脂肪肝的中医药治疗提供参考。 相似文献
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目的:探讨高原藏族酒精性肝病的病理改变特点,并与国内平原和国外者比较。方法 150例嗜酒者作肝活检病理观察。结果 分5个病理类型,其基本病变为①肝细胞变性,包括大泡性脂变,灶状小型肝细胞,灶状气球变样;②肝细胞灶状坏死伴中性粒细胞浸润;③窦周纤维化以致发展结节性肝硬变。肝脏的病变程度与饮酒量密切相关,损害程度明显重于国内平原,轻于欧美,与日本相近。结论:与高原缺氧环境、种族差异、喜饮酒及饮食习惯有 相似文献
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目前 由于过量饮酒而引起的股骨头缺血性坏死(Avascular Necrosis of the Femoral Head,ANFH)的临床报道越来越多,该病常见于青壮年,致残率高:近年来,祖国医学对酒精性股骨头缺血性坏死进行理论探讨和研究,并结合实践,提出一些较为有效的治疗方法。 相似文献
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非酒精性脂肪肝病(NAFLD)是一种肝组织病理学改变与酒精性脂肪肝类似但无过量饮酒史的临床综合症状,它的发病机制目前尚不清楚,但瘦素在其中所起到的重要作用受到越来越高的重视:本文就目前国内外瘦素及瘦素抵抗在非酒精性脂肪肝发病中作用的研究现状做一综述。 相似文献
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癫痫是以突发意识障碍、四肢抽搐为主要临床表现的一种神经系统慢性疾病.目前其发病机理尚不明确,而西药治疗是癫痫的主要手段,但西药治疗毒副作用大,且治疗周期较长.近年来随着中医药的不断发展,发现中医药在治疗癫痫方面具有独特的优势,因其疗效肯定且毒副作用小越来越被患者接受.为探讨相关中医药疗法在癫痫的研究进展,笔者通过查阅相... 相似文献
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Prasad P. Torkadi I. C. Apte A. K. Bhute 《Indian journal of clinical biochemistry : IJCB》2014,29(1):79-83
Alcoholic liver disease (ALD) is due to excessive alcohol intake for long duration. Distinguishing ALD from non-ALD (non-alcoholic steatohepatitis, hepatitis of viral origin) is difficult as patient may deny alcohol abuse. Clinical examination, histology and serology may not differentiate these conditions. Accurate diagnosis is important as management of ALD differs from non-ALD patients. The aim of our study was (1) To evaluate the patients of ALD and non-ALD by biochemical parameters compared to controls, (2) To assess whether these parameters can differentiate ALD from non-ALD. Study was carried out on 50 patients of ALD in group I and 35 patients of NASH (non-alcoholic steatohepatitis) and acute viral hepatitis each in group II. Age matched healthy controls n = 50. Selection criteria—history of alcohol intake (amount and duration), clinical examination, sonography of abdomen, serum alanine transaminase (ALT) and bilirubin levels. Blood samples were analyzed for bilirubin, aspartate transaminase (AST), ALT, alkaline phosphatase (ALP), gamma glutamyl transferase (GGT) by kinetic method. Statistical analysis was done by Student unpaired ‘t’ test. Patients of ALD have raised AST/ALT ratio (De Ritis ratio) (>2), ALP and GGT compared to controls (P < 0.01).There is significant difference in AST/ALT ratio, serum GGT and ALP in ALD group compared to that in NASH and acute viral hepatitis (P < 0.05). This study suggests that De Ritis ratio >2 in ALD patients may be due to alcohol induced hepatic mitochondrial injury and pyridoxine deficiency. High GGT and ALP values may indicate enzyme induction by alcohol and mild cholestasis. Thus ALD patients have severe hepatic damage. De Ritis ratio <1 and normal to mild elevation in GGT level in NASH and acute viral hepatitis suggest mild hepatic injury of non-alcoholic origin. Our study concludes that ALD patients can be differentiated from NASH and acute viral hepatitis with certainty by measuring serum AST/ALT ratio, GGT and ALP. These biochemical parameters may help clinicians to support the diagnosis of ALD and non-ALD. 相似文献
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