创新型企业成长动力机制的系统动力学解释

尝试运用系统动力学的原理与方法,构建创新型企业成长动力机制的系统动力学模型,并在此基础上分析创新型企业成长动力相互作用机理。     

肿瘤抑制因子Caliban相互作用蛋白的筛选和验证

为了研究Caliban的肿瘤抑制机制,通过酵母双杂交的方法筛选得到了4个新的Caliban相互作用蛋白:Bip2、Uba2、RpS27A和CG7182.它们的功能涉及转录调节、肿瘤抑制和泛素化修饰等过程.通过免疫共沉淀证实了Bip2与Caliban在体外结合,并发现在果蝇体内过表达Bip2可以抑制p53的转录.这些结果为研究Caliban的肿瘤抑制功能提供了基础.     

DC-DC BUCK功率变换器的动力学建模及其动力学行为研究

首先利用KCL和KVL定律导出了三阶DC-DC BUCK功率变换器的分段光滑的动力学方程,然后用数值方法研究了误差放大器的放大倍数与这种变换器的非线性动力学行为的关系。研究结果表明：随着放大倍数的增加,该变换器的输出电压变量呈现混沌、周期运动,且其电压转换效率在负载电容较大时,随电阻R1(即放大倍数)增加而增加,在负载电容取较小值时,随R1增加而减小。     

串联亲和纯化技术筛选hCLP46的相互作用蛋白

hCLP46(human CAP10-like protein46)是从MDS-AML患者的CD34+干细胞cDNA文库中筛选出的基因.我们利用串联亲和纯化技术来筛选与hCLP46有相互作用的蛋白.通过体内交联-甘氨酸洗脱策略,检测到7条有差异的蛋白带,经液相色谱-质谱联用鉴定,得到了CNX和PDI等一系列内质网伴侣蛋白.所以hCLP46可能是一个糖蛋白,其成熟过程利用了BiP/Grp94和CNX/CRT 2套伴侣蛋白系统.     

Dynamics of the atmosphere of Jupiter

Atmospheric jets and vortices on Jupiter persist for decades in the presence of vigorous turbulence which might be expected to destroy organized flows. The penetration depth of the jets into the planet has been a major question, and new data from the NASA Galileo entry probe suggest that they are not shallow atmospheric phenomena. Numerical simulations and Galileo orbiter data promise further progress in the near future.     

CCDC189 affects sperm flagellum formation by interacting with CABCOC01

Multiple morphological abnormalities of the sperm flagella(MMAF) are one of the major causes of male infertility and are characterized by multiple defects.In this study,we found that the coiled-coil domain-containing 189(Ccdc189) gene was predominantly expressed in mouse testes and that inactivation of the Ccdc189 gene caused male infertility.Histological studies revealed that most sperm from Ccdc189-deficient mice carried coiled,curved or short flagella,which are typical MMAF phenotypes.Immunoe...     

创新Meme的系统动力学模型

创新管理需要创新,引入Meme学说是举措之一.Meme是一个表达文化传播的单位,一个可以不断复制的单位.传统的创新管理强调细节、强调管理制造创新,而Meme的观点不同,强调"喜悦"、强调"末世英雄"的复制和扩散."创新Meme"由"好奇Meme"、"情绪Meme"、"英雄Meme"和"末世Meme"所组合,它是创新活动的文化土壤.模拟说明,创新Meme携带者曲线呈现S型成长模式,由少而多最终饱和,潜在的敏感人群曲线呈现倒S型发展,由多而少最终衰减到零.创新Meme在单位时间的传播速度呈现钟型曲线;规模越大,创新Meme的传播速度越小;创新Meme的传播速度峰值越大波峰到来的时间越晚.     

原始创新动力问题探讨

原始创新在创新活动中的逻辑地位很高,但它在企业创新活动中的实际地位却较低,这便形成了原始创新的动力缺乏问题。解决原始创新动力缺乏问题的出路在于科技金融创新,以吸引社会资本进入原始创新活动,在创新的早期阶段就能实现生产要素的成功聚集,并进而实现生产要素的新组合。具体做法可参照国外创设金融特区和高科技园区金融服务体系的经验,在北京的中关村等地设立科技金融创新试验区。     

Social Dynamics of an On-Line Scholarly Debate

This article focuses on different means of constructing a scholarly on-line debate related to the field of science, technology, and society. The study shows how scientific interactions are reproduced in a new medium while, simultaneously, some users take advantage of new possibilities offered by the medium. The first section analyzes how the debate emerged, was constructed, and subsequently revealed the heterogeneity of goals and ideas among the participants. The second section discusses the practices that the participants explored to make the debate evolve. Two attitudes, identified as strategic and tactical, were observed. The tactical practices were to enable the emergence of a sense of community. From this perspective, the way some participants sustained mobilization and stimulated participation are analyzed. The strategic attitude is illustrated through the behavior of those who tried to be the leaders in the debate.     

Dynamics of impulsive neutral-type BAM neural networks

In this letter, the existence and the global exponential stability of piecewise pseudo almost periodic solutions (PAP_T) for bidirectional associative memory neural networks (BAMNNs) with time-varying delay in leakage (or forgetting) terms and impulsive are investigated by applying contraction mapping fixed point theorem, the exponential dichotomy of linear differential equations and differential inequality techniques. Furthermore, we give an explanatory example to illustrate the efficiency of the theoretical predictions.     

企业集群中的创新传播动力学研究

研究了企业集群中的创新传播过程,基于复杂网络上传染模型研究的新进展,在分类混合假设条件下,分析了集群知识系统中SIR模型的创新传播过程,表明传播的动力学结构具有层级性,是从度大的结点群一直向度小的结点群传播;集群知识系统中度大的结点是创新的早期采用者,能起到意见领袖的作用。     

The Rhetorical Dynamics of Gender Harassment On-Line

This article compares two extended interactions that took place recently on the Internet, one from a recreational Internet Relay Chat (IRC)channel, and the other from an academic listserv discussion group. The two interactions exhibit similar gender dynamics, which can be characterized as harassment of female by male participants. This harassment takes different forms, in keeping with the possibilities inherent in the two modes of computer-mediated communication. Whereas female participants on IRC are kicked off the channel, in the discussion group harassers must rely exclusively on language to intimidate and silence. This "rhetoric of harassment" crucially invokes libertarian principles of freedom of expression, constructing women's resistance as "censorship." A rhetorical analysis of the two harassment episodes thus sheds light on the means used to construct and maintain asymmetrical gender and power dynamics in different modes of CMC.     

国家科技基础条件平台的系统动力学分析

本文利用系统动力学的定性分析与定量分析相结合的原理和方法建立了国家科技基础条件平台的仿真模型，并通过所建模型的动态模拟，讨论分析了国家科技基础条件平台的系统结构及运作机制，并以平台制度体系建设为例进行了政策实验。本文的研究结果表明：系统动力学方法是研究国家科技基础条件平台中各种因素之间的错综复杂关系的有效手段，平台的政策实验为平台建设决策提供了科学的依据和有力的支持。     

员工隐性知识传播的系统动力学模型研究

隐性知识是形成企业核心竞争力的基础和源泉.在深入分析隐性知识传播系统各组成部分特征的基础上,比较隐性知识传播过程和传染病传播过程的相似性,阐述了用传染病模型研究隐性知识传播机制的可行性,建立了员工隐性知识传播的传染病模型,编制相应的DYNAMO程序,并模拟华安公司知识传播过程,分析了知识传播过程中各因素的关系及各因素随时间的变化规律,提出了提高该公司隐性知识传播效率的措施.     

动态竞争理论的研究述评与批判

自上个世纪80年代开始,在国外战略管理研究领域兴起了一股关注企业间竞争攻击与反击互动的动态竞争研究浪潮。然而,国内对动态竞争的研究较晚,因此目前尚未形成对动态竞争理论与研究方法的系统认识。批判地回顾了动态竞争理论、方法与结论,揭示出各竞争要素之间的关系,并分析了动态竞争研究存在的局限和未来研究方向。     

Dynamics of the shell class of tensegrity structures

A tensegrity structure is a special truss structure in a stable equilibrium, with selected members designated for only tension loading, and the members in tension form a continuous network of cables separated by a set of compressive members. This paper develops an explicit analytical model of the nonlinear dynamics of a large class of tensegrity structures, constructed of rigid rods connected by a continuous network of elastic cables. The kinematics are described by positions and velocities of the ends of the rigid rods, hence, the use of angular velocities of each rod is avoided. The model yields an analytical expression for accelerations of all rods, making the model efficient for simulation, since the update and inversion of a nonlinear mass matrix is not required. The model is intended for shape control and design of deployable structures. Indeed, the explicit analytical expressions are provided herein for the study of stable equilibria and controllability, but the control issues are not treated in this paper.     

一个维基百科编辑冲突动力学模型

对维基百科编辑中的冲突与协调的研究有助于深化对社会化创新中内在协调机制的理解。在T9r9k等人所提的维基编辑动力学模型的基础上,本文提出一个考虑狂热者影响的协同编辑冲突动力学模型。通过基于Agent建模分析,所提出的模型复现了从"单一冲突"到"间歇性冲突"再到"持续冲突"的相变。进而,本模型还展示了比T9r9k等的模型更为丰富的动力学形态。本文工作为维基百科编辑中所观察到的三种冲突模式提供了一种新的解释,并对社会化创新项目中的观点冲突协调有一定启发意义。     

草莓苗圃节肢动物多样性动态监测

质优量足的草莓苗是大棚草莓生产的基础,但目前对其苗圃害虫的组成和动态了解贫乏。本研究采用黄色粘虫板在草莓的苗圃系统调查主要节肢动物组成和季节性动态变化,发现在苗圃早、中期的7月和后期的9月初,节肢动物多样性指数、物种数和总个体数相对较高,其中植食者占有很高的比例。烟粉虱、蓟马和蚜虫是草莓苗圃节肢动物群落的优势种群。