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P. Pragathi P. V. Bharath Kumar P. Amar Kumar M. Ramakanth Reddy V. Sravani J. Neeraja Eapen Reeba Mary K. Gopalakrishna 《Indian journal of clinical biochemistry : IJCB》2005,20(2):195-197
Adenosine deaminase (ADA) and 5′-nucleotidase (5′-NT) activities were measured in sera of patients with ovarian cancer and
patients with benign ovarian tumour. The results were compared with that of a control group consisting of healthy women. ADA
levels were significantly increased (P<0.001) in the ovarian cancer group (n=50) but not in the benign group (n=28) when compared
to the controls (n=20). The results indicate that ADA and 5′-NT levels may help to differentiate malignant conditions from
benign tumours of the ovary in addition to the existing tests such as serum CA-125 levels and histopathological study. 相似文献