A test strip for the estimation of urea in serum

We have developed a biostrip for determination of urea in serum. The test strip is based on enzymatic assay where urease has been immobilized on the chromatographic paper along with chromogen, phenol red. The chromogen is easily soluble in water and does not require other components for the color change. Serum urea reacts with urease and water to liberate ammonia and carbon dioxide. The liberated ammonia changes the pH of the reaction medium, which is monitored by the chromogen phenol red. A single step working reagent strip has been developed and the reaction is completed within 50 seconds at room temperature. With this test strip urea concentration is measured in serum as low as 0.15 g/L. The speed and convenience of determining urea in serum by this strip instantly makes it well suited for individuals, physicians and emergency centres.     

Evaluation of sevafilachek immunoassays and rapid ICT-filariasis test for detection of bancroftian filariasis

A comparative analysis was made on the utility of SEVAFILACHEK-stick based immunoassays and commercially available ICT-filariasis test to detect active infection in different groups of bancroftian filariasis. The SEVAFILACHEK immunoassays were found to be useful to detect filarial infection in microfilaraemia and in a significant number of clinical filarial cases with acute, chronic and occult clinical manifestations. In the clinical cases, microfilariae are not usually detected in peripheral circulation. Employing SEVAFILACHEK assays 6 and 5 of the 7 samples of patients with chronic filarial disease, and 6 and 5 of 6 microfilaraemic cases gave positivity for filarial IgG antibodies and antigen respectively. Four of the 6 occult filarial samples were positive for antibodies and antigen. Filarial antigen was detected by ICT-filariasis test in blood samples of all the 6 microfilariaemic cases, 1 chronic filarial and 2 occult filarial samples. The main advantage of ICT assay is its rapid format and convenience for field use.     

水压试验用法兰盖的厚度计算

众所周知,压力容器竣工后必须按规定进行水压试验,用于全面考核容器的强度.因此必需对所有管口用临时法兰盖进行密封以满足水压试验要求.本文列举了几种临儋时法兰盖的厚度计算方法供大家参考.     

基于改进的双重差异驱动赋权法的科技成果评价

将纵横向拉开档次法运用到"时序立体数据"中,将动态综合评价问题转换为静态的群体评价问题;为解决传统差异驱动赋权关于评价指标的敏感性问题,采用聚类分析先对专家分组有效减少实际专家人数,再运用双重差异驱动法对专家组赋权,最后得到24项科技成果的综合排名。实证研究表明:从整体差异出发的指标赋权方法和基于聚类分析的双重差异专家赋权法在综合评价中具有稳定性和连续性。     

一种基于多通道分解的图像测试信号设计方法

HVS中多通道分解模型用于度量误差图像空间尺寸的视觉感受,为了降低主观评价实验方法的条件要求,建立了一种基于多通道分解的图像测试信号设计方法。该方法通过控制白噪声在频域存在的区间,即白噪声经正交变换、掩膜量化矩阵,产生信噪比相同且空间尺寸不同的测试图像信号。分析和实验表明,多通道分解测试图像信号产生一对与高频和低频对应的误差图像,其信噪比基本相等但其空间尺寸的视觉感受不同,有利于考察与视觉感知相吻合的图像评价方法。     

高校考务管理信息系统的设计与实现

运用信息技术,开发综合考务管理信息系统,加速高校教务管理的改革进程。以开发全国大学英语4、6考务管理系统为例,讨论了高校考务管理信息系统开发设计原则及模块功能的分析。通过本系统的开发,实现教务的分级管理、规范化管理、信息共享。     

通用等级考试管理系统设计与实现

针对各类等级考试管理软件繁多,不便于管理的问题,提出了通用等级考试管理系统方案,建立了通用等级考试管理系统模型,设计了相应的考试管理业务逻辑规则及其流程工作模式,并阐述了在VB平台下实现系统所采用的关键技术及主要算法。     

基于虚拟仪器的电主轴性能测试平台的研制

电主轴是数控机床三大高新技术之一,作为数控机床核心功能部件,其国产化对我国数控机床发展有着十分重要的意义。本文介绍了电主轴主要性能参数指标,并设计基于虚拟仪器的电主轴性能测试平台,应用于生产过程中的质量控制。     

泄漏电流测量仪测量结果不确定度分析评定的探讨

本文主要关于泄漏电流测量仪的检测结果不确定度的分析评定方法进行研究。家电、电线电缆、电力、医疗器械等行业普遍使用泄漏电流测量仪进行泄电的安全测量,在计量管理中泄漏电流测量仪用于安全防护用的强检计量器具,使用单位要求提供其测量结果不确定评定。现提供在工作中总结的不确定度分评定方法析与大家共同探讨。     

Recent insights on biochemical and molecular basis for developing antihaemostatic agents: A review

The normal coagulation process is initiated by disruption and exposure of the subendothelial components of blood vessels. Platelets adhere to subendothelium-bound von Willebrand factor via glycoprotein (GP) Ib complex. This initial interaction per se and the release of platelet agonists transduce signals that leads to the rise in intracellular Ca2+ which induces shape change, prostaglandin synthesis, release of granular contents and conformational changes in platelet Gp IIb-IIIa. Gp IIb-IIIa in activated platelets binds fibrinogen and other adhesive proteins and mediates platelet cohesion the primary haemostatic plug. Furthermore, the activated platelets due to aggregation, result in the formation of fibrin (secondary hemostasis). Normally the haemostatic process plays a delicate balance between keeping the blood in the fluid state to maintain flow and rapidly forming an occluding plug following vessel injury. Thrombosis occurs because of alteration in this delicate balance. Arterial thrombosis occurs in the setting of previous vessel wall injury mostly because of atherosclerosis, while venous thrombosis occurs in areas of stasis. The recent advances in understanding of the haemostatic process have led to a better understanding of the mechanism of action of many antithrombotic drugs and identification of new targets for drug development. The molecular target of the ticlopidine has been identified. Large numbers of IIb-IIIa inhibitors have been developed. The mechanism of action of heparin has been defined at the molecular level. As a result, a synthetic pentasaccharide, based on antithrombin-binding domain of heparin, has been developed and tested successfully in clinical trials. New generation direct thrombin inhibitors are being developed. Factor Xa has a critical position at the convergence of intrinsic and extrinsic pathway. The clinical tolerability and the efficacy of low molecular weight heparins has established that inhibition of further thrombin generation, by blocking factor Xa alone can be an effective way of preventing thrombus growth without inactivating thrombin. A large number of specific factor Xa inhibitors are under development. Some of these are in preliminary clinical trials and appear to be promising. Future clinical trials will determine whether these new drugs will provide better risk-benefit ratio in treatment of thrombotic disorders. Similarly role of thrombolytics has been clearly established in many diseases including coronary artery disease.     

基于数据格式支持机制的自动化渗透测试框架

Backtrack4是功能最全面的一款测试平台,但由于数据交换处理机制的缺失使得它难以胜任高效的测试需求.设计了相应的数据格式支持机制,并依此开发了一个渗透测试框架(PTF).该框架会自动使用有关的渗透测试工具进行信息探测、漏洞评估、报告生成.真实网络环境中的实验验证了PTF能高效完成自动化渗透测试,进而大幅提升了使用Backtrack4进行渗透测试的有效性.     

数字逻辑电路测试笔仿真研究与试验

设计一种具有用途广泛、携带方便、体积小、重量轻、结构精巧、操作简单等优点的既可作为多用途信号源,又可以测量数字电路逻辑状态的测试笔。这种测试笔既具备测试输出占空比可调的脉冲波形、输出单脉冲或脉冲串、逻辑电平的多种功能,还可实现仪器功能自检。通过仿真与试验,验证明了该设计的正确性和有效性。     

作业成本法在我国企业的应用研究

阐述我国企业在作业成本法上存在的认识误区,分析作业成本法在我国企业中应用的难点,指出作业成本法实施的步骤。     

交流异步电动机加载试验台的研制及应用

电动机是煤矿安全生产中的重要设备,其性能直接影响煤矿设备的正常运转,电动机使用前需要进行性能测试。交流异步电动机加载试验台实验项目包括绕组绝缘电阻测定、空载检查、分级载荷试验、超载试验等。所设计的交流异步电动机加载试验台能够为矿用电动机的性能提供精确的参考数据。     

基于MSC.DYTRAN的安全气囊性能仿真分析

安全气囊属于汽车被动安全范畴,为了使其能真正地起到保护乘员的作用,必须对它的性能进行测试.本文介绍了在有限元分析软件MSC.Patran和Dytran环境下,对安全气囊建立有限元模型进行性能仿真分析的方法.仿真结果证明了分析的安全气囊性能符合各项法规的规定,证明了该仿真分析方法的可行性.     

Direct design of recursive digital filters based on a new stability test

In this paper we present an alternative approach to the direct design of 1-D recursive digital filters satisfying prescribed magnitude specifications with or without constant group delay characteristic. This method uses an iterative method to calculate the coefficients of the filter's transfer function and guarantees the stability of the designed filter using a new stability test reported by Ramachandran and Gargour. To illustrate the usefulness of the technique, examples are given.     

The biochemical womb of schizophrenia: A review

The conclusive identification of specific etiological factors or pathogenic processes in the illness of schizophrenia has remained elusive despite great technological progress. The convergence of state-of-art scientific studies in molecular genetics, molecular neuropathophysiology, in vivo brain imaging and psychopharmacology, however, indicates that we may be coming much closer to understanding the genesis of schizophrenia. In near future, the diagnosis and assessment of schizophrenia using biochemical markers may become a “dream come true” for the medical community as well as for the general population. An understanding of the biochemistry/ visa vis pathophysiology of schizophrenia is essential to the discovery of preventive measures and therapeutic intervention.     

A rapid method for plasma ammonia estimation using an indigenously purified enzyme

Determination of ammonia level in blood is important, especially in the diagnosis of hepatic disorders. An indigenously purified enzyme was used in the standardisation of the assay. The assay is a two reagent system, requires five minutes for completion and can be performed at temperature between 25–27°C. Performance of the assay was assessed by linearity, imprecision, functional sensitivity and interference studies. Lyophilised reagent I and reagent II were found stable for at least one year. The plasma level of ammonia for the controls was 13.7±7.3 μMol/L, whereas for subjects of hepatic disorders, it was 69.1±32.4 μMol/L (P<0.001). The functional sensitivity was between 2–1000 μMol/L. Within-run coefficient of variation was between 1.1–2.0% and between-run coefficient of variation was between 1.9–3.7%. The mean recovery after dilution was 99.6%. The present method can estimate ammonia up to 1000 μMol/L without dilution of sample. Assay time of five minute may be shortened to one minute. This method is suited for routine clinical use in treatment of hepatic disorders.     

大学法语四级与CEFR的等级标准关系研究

为适应新形势下的中外校际交流合作办学的要求,法语教学的内容和形式既要迎合赴法学生对欧洲语言共同参考框架的标准,又要满足国内学生对大学法语四级考试的需求。从设定标准的角度分析二者的等级对应关系,从B2标准等级序列中,在常规法语教学中协调他们之间的考级差异。     

对福建省各地市体育中考项目与计分方法的调查分析

采用文献资料法等方法对福建省各地市体育中考项目和计分方法进行分析。结果显示：福建省各地市都是以发展学生的爆发力/耐力以及心肺功能的运动项目作为考试项目,得分是以最后的平均分计算,实现学生在各项成绩上的互补,对身体残疾或丧失运动能力、有严重疾病的学生提供优惠政策。通过福建省各地市体育中考项目和计分方法的初步分析,提出不断完善考试措施,发挥其正确导向,提高学生身体健康水平,使体育中考发挥应有的功能与价值。