基于多种智能便携医疗设备的慢性病患者智慧护理系统构建

在科学技术高速发展的背景下,智能便携医疗设备的发展非常迅速,不仅能够保证检测结果的准确性,且价格也逐年降低,能够被普通百姓接受。但对于慢性病患者来说,往往单一的检测结果可能无法判断患者整体的患病情况。在此背景下,我院基于多种智能便携医疗设备,构建了慢性病患者智慧护理系统,系统整体由患者健康信息输入层、智能便携设备准备层、信息整合层、护理方法制定层、患者护理实时监管层和患者反馈层等组成。通过智能便携医疗设备的应用和软件的合理设计,有效提高了患者的护理效果。     

异步电机无速度传感器直接转矩控制研究

直接转矩控制(DTC)是一种高性能的电机调速控制方法,它通过对转矩和磁链两个信号直接进行观测和控制,省去了复杂的坐标变换,简化了控制器的结构。针对速度反馈信号易受传感器安装规范,检测精度,环境变化等多种复杂因素干扰的问题,本文对无速度传感器DTC控制系统进行研究,阐述了一种基于模型参考自适应控制的无速度传感器DTC控制方法,提高了异步电机调速系统的调速性能。     

光导纤维化学传感器的研究

光导纤维化学传感器又称光极,它是将具有分子识别功能和换能器功能的固定化试剂传感膜安装在光导纤维上,作为传感器探头,它能选择性地对多种离子和化合物进行识别,并转化为荧光、磷光,化学发光和反射光等光信号,通过光导纤维传地检测系统进行检测,光导纤维化学传感器是分析化学在80年代的一项重大发展。光导纤维化学传感器由于具有小至微米级的光纤探头,可以避免电磁的干扰,并能在高温,高压及强放射性等恶劣的环境下使用,还能通过光纤维进行遥测、检测限可达ppb以下     

基于MEMS的小型姿态检测系统设计

为了能够实现对各种载体的轨迹的有效控制,本文利用加速度传感器、陀螺传感器和磁阻传感器组成的惯性导航系统,来实现载体的姿态检测。按照姿态检测的设计要求,选取了MEMS传感器作为姿态检测的数据采集单元。其中包括一个三轴陀螺仪、一个三轴的加速度计和一个三轴磁阻传感器搭建了姿态检测系统的传感器模块。并利用STM32单片机作为主控制单元来实现数据处理,采用I2C的接口实现传感器与单片机的连接,使得单片机可以获得载体姿态的实时检测。本文所设计的姿态检测系统具有精度高、体积小、功耗小等优点,能够满足机器人平衡、云台稳定控制、游戏机、虚拟现实、人体运动检测等多种用途。     

黄酮类化合物和抗生素类药物的高效液相色谱检测技术研究

在当前的药物制备生产中,为了保证其生产质量,往往需要对药品的主要药效成分含量进行测定,而高效液相色谱法正是这样一种非常可行的检测技术,在多种药品的检测中发挥了积极作用。现本文就以黄酮类化合物与抗生素类药物这两种应用较为广泛的物质为例,对其高效液相色谱检测方法进行研究分析,以供参考。     

电力变压器内绝缘故障检测技术分析

近些年来,变压器内部故障检测技术的实施因为电子传感器技术和油气分离技术的发展,取得了飞速的进步。现在,电力变压器检测技术结合多种方法,在变压器发生故障时有成果且迅速的进行检测和评估分析,力求在萌芽状态把隐患彻底消除。本文对电力变压器内部故障检测技术进行了分析,重点阐述了油色谱检测和红外技术检测。     

汽车电控系统常规传感器测试系统的研究

针对汽车常用的传感器设计一专用的测试系统,通过系统方便快捷的实现对汽车中多种传感器的快速检测,查找汽车所存在的故障,尽早排除以保证汽车的安全行驶。     

气相色谱法测定大米中马拉硫磷与甲基嘧啶磷

采用气相色谱法对大米中马拉硫磷和甲基嘧啶磷进行测定方法研究,检测大米中马拉硫磷与甲基嘧啶磷得到良好色谱分离。样品前处理方法简单,避免了被测物质的损失。方法可操作性强,能够满足实际样品的检测要求。     

苦参素注射液有关物质检查方法建立

目的:通过对有关物质检查方法比较,建立本品有关物质检查方法。方法:采用高效液相色谱,色谱柱选用氨基色谱柱,以0.1mol/L磷酸二氢钠-甲醇-乙腈-高氯酸钠(900∶30∶40∶30)为流动相,流速1.0ml/min,220nm为本品的检测波长,氧化槐果碱与苦参素分离度符合规定,氧化槐果碱线性为3.0~18.0ug/ml,专属性试验表明供试品与降解产物可有效分离,峰纯度符合规定,物料平衡,苦参素检测限为3.1ng,氧化槐果碱检测限为1.9ng,溶液稳定性试验结果表明供试品溶液在8小时内稳定。结论:所建立含量测定方法可行,可用于测定本品有关物质。     

逆流色谱仪转速、温度和输入输出通道一体化控制的研发

本文中逆流色谱仪即指高速逆流色谱仪,是一个新型的高纯度分析分离设备,其原理是用充满两相溶剂的螺旋管作为分离单元在离心力场中按一定规律运动,当被分离的混合物通过分离单元时,由于不同物质在两相溶剂中具有不同的分配特性将会产生物质的分离排列.它已在农业、环境、材料、化工、海洋生物以及无机离子、保健品原料、食品添加剂和化妆品等众多领域获得了广泛的应用,尤其是在天然产物活性成分的分离纯化领域倍受重视.目前国内生产的一般逆流色谱仪中,只有简单的控制功能不能充分发挥仪器的作用,因此针对这一缺点本项目主要的开发工作是利用单片机技术进一步提高逆流色谱仪自动化控制水平,进行逆流色谱仪转速、温度和输入输出通道一体化控制的研发.通过表项目的开发对逆流色谱如温度检测、显示、超限报警,直流电机转速检测、控制,通过手动即时检测及程控巡回检测控制等,提高逆流色谱仪性能,满足社会需求,进而促进逆流色谱仪的进一步使用和发展.     

化工厂挥发类爆炸性气体泄漏检测系统的设计

针对当前传统的化工厂危险气体泄漏检测系统中,在多层爆炸性气体和弱爆炸性气体的条件下,传统的智能检测方法存在较大误差的问题。设计了一套基于虚拟仪器的气味挥发类中药品质测量系统,利用气敏传感器组成阵列进行前端数据采集,采用USB-DATA AD816数据采集器实时采集信号,以LabVIEW2009为开发平台,通过改进K均值聚类对多层爆炸气体聚类分析,通过弱爆炸信号加强,对混合爆炸气体信号进行有效的分类测量,实现化工厂挥发类爆炸性气体泄漏检测,实验结果表明,该方法能够较好的实现检测功能,克服传统方法存在的弊端。     

Integration of programmable microfluidics and on-chip fluorescence detection for biosensing applications

We describe the integration of an actively controlled programmable microfluidic sample processor with on-chip optical fluorescence detection to create a single, hybrid sensor system. An array of lifting gate microvalves (automaton) is fabricated with soft lithography, which is reconfigurably joined to a liquid-core, anti-resonant reflecting optical waveguide (ARROW) silicon chip fabricated with conventional microfabrication. In the automaton, various sample handling steps such as mixing, transporting, splitting, isolating, and storing are achieved rapidly and precisely to detect viral nucleic acid targets, while the optofluidic chip provides single particle detection sensitivity using integrated optics. Specifically, an assay for detection of viral nucleic acid targets is implemented. Labeled target nucleic acids are first captured and isolated on magnetic microbeads in the automaton, followed by optical detection of single beads on the ARROW chip. The combination of automated microfluidic sample preparation and highly sensitive optical detection opens possibilities for portable instruments for point-of-use analysis of minute, low concentration biological samples.     

Enhanced H-filter based on F?hr?us-Lindqvist effect for efficient and robust dialysis without membrane

A novel microfluidic device for highly efficient and robust dialysis without membrane is highly desired for the development of portable or wearable microdialyzer. Here we report an enhanced H-filter with pillar array based on Fåhræus-Lindqvist effect (F-L effect) for highly efficient and robust membraneless dialysis of simplified blood for the first time. The H-filter employs two fluids laminarly flowing in the microchannel for continuously membraneless dialysis. With pillar array in the microchannel, the two laminar flows, with one containing blood cells and small molecules and another containing dialyzate solution, can form a cell-free layer at the interface as selective zones for separation. This provides enhanced mixing yet extremely low shear for extraction of small molecules from the blood-cell-containing flow into the dialyzate flow, resulting in robust separation with reduced cell loss and improved efficiency. We demonstrate this by first using Chlorella pyrenoidosa as model cells to quantitatively study the separation performances, and then using simplified human blood for dialysis. The advanced H-filter, with highly efficient and robust performance for membraneless dialysis, shows great potential as promising candidate for rapid blood analysis/separation, and as fundamental structure for portable dialyzer.     

Investigation of array robustness to sensor failure

The presence of uncertainties in the array response, due to sensors operational malfunctions and environmental effects, results in a performance degradation often greater than the application requirements can afford. Various attempts have been made to measure the effect of the presence of uncertainties on the performance of direction-finding (DF) algorithms and, moreover, several methods have been developed to either detect or partly rectify the resulting defects in performance and hence improve the robustness of the array system. However, the impact of sensor response uncertainties on the ultimate array DF capabilities, as they are determined by the array manifold characteristics, has not been considered thoroughly. In this paper, the sensitivity of array DF capabilities to sensor response errors is first formulated and investigated. Robustness and reliability measures are then proposed. Such measures can be used as tools for the evaluation of each sensor's importance within the array geometry and as criteria for the comparison of a number of array geometries.     

AdHoc网络AODV路由协议在S3C6410中的研究与应用

文章主要分析和研究在嵌入式linux系统下AODV路由协议的实现方法,基于开源协议AODV实现了一种在Linux系统中基于Netfilter功能框架的无线传感器网络,实现了路由查询、更新和维护等过程。并且在S3C6410处理器上成功移植适用于嵌入式Linux系统的AODV路由协议,并实现AdHoc网络的功能。网络性能的测试说明,所移植的Linux系统各部分运行稳定,AdHoc网络运行良好。     

一种未知信源数目的声矢量阵DOA估计算法

针对声矢量DOA估计问题,根据声矢量阵的特点,结合MVDR算法的思想,本文提出了一种声矢量阵DOA估计新算法。该算法将声矢量阵振速通道的数据协方差矩阵相加得到新的协方差矩阵,然后结合声矢量阵声压通道的数据协方差矩阵,通过类似于V-MVDR算法的角度扫描过程实现目标的DOA估计,该算法无需已知信源数目且不需要特征值分解运算,具有良好的DOA方位估计和分辨性能,计算机仿真结果验证了本文算法的有效性。     

无线传感网入侵检测技术研究

无线传感网开放的访问和有限的资源使其极易受到各种攻击,需要有效的入侵检测技术发现并识别各种安全威胁。对目前的入侵检测系统进行了简要的介绍,探讨了无线传感网面临的各种威胁,对无线传感网入侵检测技术进行深入的研究,最后指出各种技术的综合使用是无线传感网入侵检测系统的发展方向。     

A portable lab-on-a-chip system for gold-nanoparticle-based colorimetric detection of metal ions in water

Heavy metal ions released into various water systems have a severe impact on the environment and human beings, and excess exposure to toxic metal ions through drinking water poses high risks to human health and causes life-threatening diseases. Thus, there is high demand for the development of a rapid, low-cost, and sensitive method for detection of metal ions in water. We present a portable analytical system for colorimetric detection of lead (Pb²⁺) and aluminum (Al³⁺) ions in water based on gold nanoparticle probes and lab-on-a-chip instrumentation. The colorimetric detection of metal ions is conducted via single-step assays with low limits of detection (LODs) and high selectivity. We design a custom-made microwell plate and a handheld colorimetric reader for implementing the assays and quantifying the signal readout. The calibration experiments demonstrate that this portable system provides LODs of 30 ppb for Pb²⁺ and 89 ppb for Al³⁺, both comparable to bench-top analytical spectrometers. It promises an effective platform for metal ion analysis in a more economical and convenient way, which is particularly useful for water quality monitoring in field and resource-poor settings.     

Rapid β-human chorionic gonadotropin detection in urine with electric-double-layer gated field-effect transistor biosensors and a handheld device

In this experimental study, a portable biosensor was developed to detect β-human chorionic gonadotropin (β-hCG), which is extensively used in pregnancy tests and serves as a biomarker for ectopic pregnancy. The sensor used is an electric-double-layer field-effect transistor biosensor with the extended-gate design. Bias voltage is applied on the sensor to measure the resulting drain current signals. Gold electrode surface is functionally activated with an anti-β-hCG antibody to capture β-hCG protein. Fluorescence imaging technique is utilized to confirm the surface functionalization. The biosensor demonstrates a dynamically wide range of molecules as detection targets at very low sample concentrations, which shows the potential to detect ectopic pregnancy in very early stages and easily keep track of its periodic changes. It can be produced en masse and does not use additional labels/reagents or pre-processing techniques for the sample. This biosensor can significantly reduce the manufacturing costs and is comparable with the currently available commercial ß-hCG assays. It is suitable for early diagnosis of ectopic pregnancy with low cost and easy operation at home with urine samples.     

RBF神经网络在传感器故障诊断中的应用研究

本文针对传感器在自动化系统中的重要性,指出了传感器故障诊断的必要性、可行性以及实现的基本方法。根据神经网络的原理与特点,阐述了RBF神经网络的基本理论和优点,提出了一种基于RBF神经网络用于传感器故障诊断的思路和方法。