Erythrocytic adenosine deaminase in post myocardial infarction angina patients

A comparative study on the levels of erythrocyte adenosine deaminase and lipid peroxidation has been undertaken in post myocardial infarction angina patients along with age and sex matched healthy individuals serving as control. Present findings show that levels of adenosine deaminase is highly elevated in post myocardial infarction angina patients compared to healthy persons. Malondialdehyde levels are also significantly increased in post myocardial infarction angina patients. The study shows that adenosine deaminase has an important implication in ischemic myocardial syndrome.     

Studies on the age dependent changes in serum adenosine deaminase activity and its changes in hepatitis

Serum Adenosine deaminase (ADA) activity in normal healthy control subjects increases upto 30 years, remains steady between 31–60 years of age and shows a steep increase in the age group of 61–70 years. This was compared with serum aspartate transaminase (AST) and alanine transaminase (ALT) activity which also showed a gradual increase upto 40 years of age and decreased thereafter. The activities of serum ADA, AST and ALT increased in patients with hepatitis of all age groups compared to their respective controls. The degree of increase in the activities of the above enzymes in hepatitis, decreased with age. The present study also shows that while studying serum ADA activity in hepatitis for diagnostic purposes, the value obtained in a particular age group should be compared with normal range of values for the respective age group only.     

Adenosine deaminase and protein tyrosine phosphatase activities in liver and peritoneal macrophages of streptozotocin induced diabetic mice

Adenosine deaminase and protein tyrosine phosphatase activities in liver and peritoneal macrophages were estimated in control, streptozotocin induced diabetes and insulin treated diabetic groups of Swiss albino mice. Both the enzyme levels were elevated while glycogen content decreased in the liver of diabetic group of animals as compared to controls, while in insulin treated group, they were comparable to control levels. In macrophages also, both adenosine deaminase which plays an important role in their maturation and protein tyrosine phosphatase enzyme involved in their activation were high in diabetic group, whereas in insulin treated diabetic group, the values were comparable to control levels. *** DIRECT SUPPORT *** A00FN011 00003     

Adenosine deaminase and C-reactive protein in cerebrospinal fluid for differential diagnosis of tubercular meningitis in children

Adenosine deaminase and C-reactive protein in CSF were assessed in 72 cases of Tubercular meningitis, 24 cases of partially treated pyogenic meningitis, 20 cases of Aseptic meningitis and 8 cases of febrile seizures. Mean Adenosine deaminase value was 12.12±3.13 IU/L for Tubercular meningitis group. It was significantly higher (p<0.001) as compared to partially treated pyogenic meningitis (5.39±2.70 IU/L) and aseptic meningitis (1.92±0.56 IU/L) groups. A combination of clinical criteria along with biochemical test of Adenosine deaminase and C-reactive protein in CSF increased the sensitivity of diagnosing Tubercular meningitis and differentiating it from other forms of meningitis at an early stage.     

Evaluation of serum adenosine deaminase and 5′-nucleotidase activities as probable markers in ovarian cancer

Adenosine deaminase (ADA) and 5′-nucleotidase (5′-NT) activities were measured in sera of patients with ovarian cancer and patients with benign ovarian tumour. The results were compared with that of a control group consisting of healthy women. ADA levels were significantly increased (P<0.001) in the ovarian cancer group (n=50) but not in the benign group (n=28) when compared to the controls (n=20). The results indicate that ADA and 5′-NT levels may help to differentiate malignant conditions from benign tumours of the ovary in addition to the existing tests such as serum CA-125 levels and histopathological study.     

Stability studies of common biochemical analytes in serum separator tubes with or without gel barrier subjected to various storage conditions

Introduction

The collected and shipped blood samples are exposed to a various extra-analytical factors prior to analysis. The aim of the study was to determine the stability of analytes in serum gel tubes and plain tubes exposed to a range of storage temperatures and times after centrifugation.

Materials and methods:

Fifteen healthy volunteers were recruited and venous blood was collected into four tubes, two with and two without gel separator. Analyzing the baseline samples in 30 min, all were stored at 4ºC or 24ºC for 6, 12, 18, 24, 30, 36, 48 and 72 hours and 1 week. Sixteen biochemical anaytes were measured on each sample. Variations remained under the desirable bias considered as clinically insignificant.

Results:

On day three, most analytes remained stable including albumin, protein, creatinine, cholesterol, triglycerides, gamma-glutamyl transferase (GGT), alkaline phosphatase (ALP), alanine aminotransferase (ALT), creatine kinase (CK), lactate dehydrogenase (LD) regardless of tube types. Glucose concentration decreased markedly (P = 0.001) beginning from the first hours of storage in plain serum. The stability maximized for the analytes including glucose, total bilirubin, urea nitrogen (BUN), uric acid stored at 4 ºC in gel tubes. Aspartate aminotransferase (AST) activity increased significantly (P = 0.002) up to 48-h, however bias was not significant clinically. High density lipoprotein (HDL) concentration was stable in gel tubes at 24 ºC, in plain tubes at 4 ºC stored up to 36-h.

Conclusion:

Serum gel or non-gel tubes might be used interchangeably for 11 analytes chilled or at 24 ºC, whereas some restrictions must be applied for glucose, AST, BUN, HDL, and uric acid.     

我国各地区人力资本投入计量实证研究

为了科学合理地对我国各地区人力资本的投入进行计量，结合我国实际，采用基于工业劳动者收入的人力资本计量模型，将农林渔等业考虑在内，对我国各地区1997-2001年平均人力资本投入量，进行了实证研究，并对结果进行了分析。     

Lipid peroxidation and antioxidant status in blood of rheumatoid arthritis patients

The main objective of the study was to assess the oxidative stress in plasma and erythrocytes of rheumatoid arthritis patients by measuring the levels of thiobarbituric acid reactive substances (TBARS), non-enzymatic antioxidants (vitamin E, C and reduced glutathione) and enzymatic antioxidants [superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GSHPx)]. This study has been conducted on twenty-two adult female rheumatoid arthritis patients and an equal number of healthy subjects. Elevated lipid peroxidation and multidirectional changes in the antioxidant defence system were noticed in patients with rheumatoid arthritis. The enhanced lipid peroxidation accompanied by disturbance in antioxidant status indicates that rheumatoid arthritis patients are more prone to free radical mediated oxidative damage.     

酶解法制取蚕蛹多肽

以蚕蛹为原料,经脱脂后,采用碱法提取蚕蛹蛋白,以双酶水解的方法制取可溶性蚕蛹多肽,最佳制取条件为固液比1：10,水解温度45℃,酶用量3%（木瓜蛋白酶：胰蛋白酶=1：1）,水解时间6h,在此条件下制备的蚕蛹多肽得率为62.5%。使用胃蛋白酶和胰蛋白酶分别水解时,多肽得率为58.7%。     

腺苷对房室结双径路传导现象的诊断价值

目的 探讨腺苷对房室结折返性心动过速患者（AVNRT）房室结双径路传导现象（DAVNP）的诊断价值。方法 对53例阵发性室上性心动过速（PSVT）患者在窦性心律下经外周静脉推注递增剂量的腺苷后观察体表心电图上房室传导时间的变化。其中18例AVNRT患者在慢径消融术后行再次腺苷检查。结果 有31例慢快径咱折返性心动过速患者中有26例出现PR间期突然跳跃达60ms以上,20例房到折返性心动过速（AVRT）及2例房性心动过速（AT）中仅2例出现此现象（P＜0.01）,18例AVNRT患者在慢径消融成功后电生理检查示8例慢径消失,6例存在DAVNP,但在静推腺苷时沿慢径下传的激动显著减少（P＜0.01）。结论 房室结双径路前传时快径路对腺苷的敏感性要高于慢径路,窦性心律下静脉推注腺苷是床边诊断房室结折返性心动过速患者双径路传导现象的有效方法,对心房程序扫描刺激未能发现房室传导时间跳跃时腺苷推注有助于房室结双径路的诊断。     

钩吻的化学成分与生物活性研究进展

钩吻主要的化学成分为吲哚生物碱类化合物,其中某些成分有显著毒理、抗肿瘤、免疫调节作用,药理活性显著,具有进一步开发利用的前景。     

BaTiO3-CoFe2O4复合多铁纳米陶瓷的制备及性能研究

采用化学共沉淀法和溶胶凝胶法制备BaTiO3-CoFe2O4两相复合陶瓷粉体,并通过成型1200℃烧结制备BaTiO3-CoFe2O4两相复合陶瓷,测试XRD和TEM,并对其介电,漏电,铁电进行了研究。XRD分析制备的BTO陶瓷为四方结构,铁电性较好,具有较大的介电常数和较低的介电损耗,CFO陶瓷为尖晶石结构,复合陶瓷具有两相结构,同时具有铁电性和磁性。     

闭环供应链活动战略对绩效影响研究

依据企业对闭环供应链中传统前向供应链和逆向供应链活动环节的关注程度,将闭环供应链活动战略划分为:全面关注战略、前向关注战略、低型关注战略和逆向关注战略;探讨了不同活动战略对企业绩效的影响.研究发现:差异显著的活动战略导致差异显著的企业绩效;全面关注战略是提升企业绩效的最优战略.最后在对研究进行总结的基础上,给出了建议和进一步研究的方向.     

模拟脑脊液在实验教学中的应用探索

在临床检验实验课中,获取和保存脑脊液标本比较困难,以添加葡萄糖、血清、氯化物及白细胞的方法制备模拟脑脊液标本,用于脑脊液检查的实验课教学,取得较好的教学效果。     

A comparative study of lens protein glycation in various forms of cataract

The aim of this study was to estimate and compare the levels of glycated protein in the lens extracted from patients with cataract of various etiologies. A total of 72 cataract lens were collected. The levels of total proteins, glucose and glycated protein in the lens were studied. Plasma protein and fasting glucose levels were also estimated. The amount of glycation of lens was significantly higher in case of hypermature senile cataract (p<0.01) when compared with other types of cataracts. The levels of lens glucose between the various types of cataracts did not differ significantly. These results indicate that the level of lens glucose alone is not the only determining factor of lens protein glycation.     

长沙市人力资源现状分析

从长沙市人口基本情况分析入手,推及人力资源的数量及其质量构成,并结合北京、上海等城市的相关情况,找出目前长沙市人力资源队伍存在的不足.希望从实践上给长沙市政府部门提供一些决策的参考依据,搞好人力资源管理的研究。     

计算流体力学在搅拌混合过程模拟中的应用

计算流体力学包括反应器中流体的质量、动量、能量守恒方程和反映所研究问题的辅助方程的数值解。它在搅拌式反应器的设计与放大中起着重要的作用。概述了模拟搅拌式反应器中流场的各种方法:搅拌桨边界条件法,内外迭代法,多重参照系法,滑动网格法,快速照相法和大涡模拟法。并通过分析各种方法的优缺点提出了进一步的研究方向:修正湍流模型,发展大涡模拟法等。     

流体机械专业本科生CAD课程教学改革

本文针对江苏大学卓越学院流体机械专业的现状,结合流体机械CAD课程的特点,通过多种教学手段,使学生理解并掌握流体机械水力部件设计方法．并会用CAD软件绘制水力部件二维木模图．利用PRO／E和UG软件绘制水力部件三维图．激发学生对“流体机械CAD”课程的学习兴趣,让学生愉快地学习这门课程,做到学有所得、能学以致用,为毕业设计打好基础．把学生培养成复合型的人才．服务于社会．．     

Automatic extraction of bilingual word pairs using inductive chain learning in various languages

In this paper, we propose a new learning method for extracting bilingual word pairs from parallel corpora in various languages. In cross-language information retrieval, the system must deal with various languages. Therefore, automatic extraction of bilingual word pairs from parallel corpora with various languages is important. However, previous works based on statistical methods are insufficient because of the sparse data problem. Our learning method automatically acquires rules, which are effective to solve the sparse data problem, only from parallel corpora without any prior preparation of a bilingual resource (e.g., a bilingual dictionary, a machine translation system). We call this learning method Inductive Chain Learning (ICL). Moreover, the system using ICL can extract bilingual word pairs even from bilingual sentence pairs for which the grammatical structures of the source language differ from the grammatical structures of the target language because the acquired rules have the information to cope with the different word orders of source language and target language in local parts of bilingual sentence pairs. Evaluation experiments demonstrated that the recalls of systems based on several statistical approaches were improved through the use of ICL.     

高职信息安全专业多形式的实践课程体系研究

研究高职信息安全专业中的实践课程体系的建设方案,提出了模拟真实环境推演、网络安全对战、信息安全个案设计等多形式的实践课程实施形式,分析不同形式的实践课程教学效果和实施要求。