Serum Ischemia-Modified Albumin in Preterm Babies with Respiratory Distress Syndrome

Infants with respiratory distress syndrome (RDS) may suffer from severe hypoxia, asphyxia. In this study, we aimed to evaluate serum ischemia-modified albumin (IMA) level as a diagnostic marker for hypoxia in preterm infants with RDS. Thirty-seven premature newborns with RDS were allocated as the study group and 42 healthy preterm neonates were selected as the control group. IMA was measured as absorbance unit (ABSU) in human serum with colorimetric assay method which is based on reduction in albumin cobalt binding. IMA levels were significantly higher in neonates with RDS as compared to the control group (P < 0.001). Cut-off value of IMA (ABSU) was 0.72, the sensitivity level was 91.9 %, the specificity was 78.6 %, positive predictive value was 79.1 % and negative predictive value was 91.7 % at RDS. Area under curve values was 0.93 (P < 0.001; 95 % CI, 0.88–0.98) in the receiver operating characteristic curve. We concluded that elevated blood IMA levels might be accepted as a useful marker for hypoxia in newborn with RDS.     

全球高校专利竞争力与科研关联度分析

研究全球重点高校专利竞争力与科研关联度。使用二维象限法分析方法发现,全球重点高校专利在二维图中具有很强的分布规律,专利竞争力与科研存在着很大的关联关系。通过y=ax+b线性拟合公式研究发现,发达国家全球重点高校的科研与专利布局意识存在很高的一致性和协调性;中国全球重点高校的线性拟合中,a值为0.211 6,低于大部分其他国家,b值为30.255 0,低于其他国家。这两个参数表明中国高校目前正处于一个特殊的发展时期,整体更倾向于发明创造、申请更多的专利进行布局,也符合中国目前的经济和科技发展历史时期。