试论作业成本法及其在我国的应用

试述了新制造环境对成本会计的冲击、作业成本法与传统成本计算系统的比较，指出作业成本法是成本会计发展的必然趋势，并提出它在我国实际应用的具体措施。     

Microfluidic rectifier based on poly(dimethylsiloxane) membrane and its application to a micropump

A microfluidic rectifier incorporating an obstructed microchannel and a PDMS membrane is proposed. During forward flow, the membrane deflects in the upward direction; thereby allowing the fluid to pass over the obstacle. Conversely, during reverse flow, the membrane seals against the obstacle, thereby closing the channel and preventing flow. It is shown that the proposed device can operate over a wide pressure range by increasing or decreasing the membrane thickness as required. A microfluidic pump is realized by integrating the rectifier with a simple stepper motor mechanism. The experimental results show that the pump can achieve a vertical left height of more than 2 m. Moreover, it is shown that a maximum flow rate of 6.3 ml/min can be obtained given a membrane thickness of 200 μm and a motor velocity of 80 rpm. In other words, the proposed microfluidic rectifier not only provides an effective means of preventing reverse flow but also permits the realization of a highly efficient microfluidic pump.     

An efficient document clustering algorithm and its application to a document browser

We present an efficient document clustering algorithm that uses a term frequency vector for each document instead of using a huge proximity matrix. The algorithm has the following features: (1) it requires a relatively small amount of memory and runs fast, (2) it produces a hierarchy in the form of a document classification tree and (3) the hierarchy obtained by the algorithm explicitly reveals a collection structure. We confirm these features and thus show the algorithm's feasibility through clustering experiments in which we use two collections of Japanese documents, the sizes of which are 83,099 and 14,701 documents. We also introduce an application of this algorithm to a document browser. This browser is used in our Japanese-to-English translation aid system. The browsing module of the system consists of a huge database of Japanese news articles and their English translations. The Japanese article collection is clustered into a hierarchy by our method. Since each node in the hierarchy corresponds to a topic in the collection, we can use the hierarchy to directly access articles by topic. A user can learn general translation knowledge of each topic by browsing the Japanese articles and their English translations. We also discuss techniques of presenting a large tree-formed hierarchy on a computer screen.     

三重螺旋模型及其在我国的应用初探

在知识经济背景下,三重螺旋模型强调"产官学"三方的互动关系。该模型指出,大学在经济和技术创新中应承担更多的任务,还主张通过"产官学"合作来推动知识发展和产业化。本文简要回顾该模型的主要内容和理论结构,并介绍国内相关研究和实践经验。基于此,本文认为三重螺旋模型形成于发达国家和高技术产业背景,在我国创新实践中应当谨慎地吸收和采用。     

六维球面中的SU(2)-轨道(英文)

利用标准的SU(2)不可约酉表示,构造了SU(2)到G2的实不可约表示.同时,研究了S6中不同的SU(2)-轨道类型,特别是3维CR-轨道.     

高新技术企业资金运营效果综合评价方法及应用研究

在高新技术企业资金运营效果评价指标体系设计基础上，运用层次分析法提出了高新技术企业资金运营效果评价方法，并对典型高新技术企业资金运营效果进行了综合评价。本文研究为高新技术企业资金运营效果评价、资金运营控制和资金管理提供了一种有效的手段。     

客观认识SCI及其在科研成果评价中的应用

在科研成果的评价中,我国现在普遍流行采用SCI评价工具。SCI作为评价科研成果的评价标准,在一定程度上具有客观性、公正性和定量化的评价效果．是目前国际上广泛承认的一种比较权威、相对客观的科研成果评价标准。在充分肯定SCI科学价值的前提下,本文分析了SCI在我国的应用,探讨了SCI自身的局限性以及带来的负面影响,以及如何正确认识、合理利用SCI。     

JCR中一个新的跨学科评价指标——期刊引证指数(JCI)及其实证研究

【目的】 探讨期刊引证指数(Journal Citation Indicator,JCI)的文献计量学特征及评价应用。【方法】 系统梳理JCI设计理念及相关理论,从InCites-JCR采集相关数据,对JCI进行实证研究。【结果】 与影响因子相比,JCI对引证时间窗口、文献类型、被引频次计数方法等设计更加合理,并且对被引频次按照学科、出版年和文献类型进行了标准化处理,能够更加合理地用于学术期刊影响力评价,尤其是期刊的跨学科评价。【结论】 JCI应用于学术期刊影响力评价具有明显的优越性,其设计体现了跨学科评价理念,能够较为客观地反映我国科技期刊的发展情况。     

LXYL-P1-2 immobilized on magnetic nanoparticles and its potential application in paclitaxel production

BackgroundLXYL-P1-2 is the first reported glycoside hydrolase that can catalyze the transformation of 7-β-xylosyl-10-deacetyltaxol (XDT) to 10-deacetyltaxol (DT) by removing the d-xylosyl group at the C-7 position. Successful synthesis of paclitaxel by one-pot method combining the LXYL-P1-2 and 10-deacetylbaccatin III-10-β-O-acetyltransferase (DBAT) using XDT as a precursor, making LXYL-P1-2 a highly promising enzyme for the industrial production of paclitaxel. The aim of this study was to investigate the catalytic potential of LXYL-P1-2 stabilized on magnetic nanoparticles, the surface of which was modified by Ni²⁺-immobilized cross-linked Fe₃O₄@Histidine.ResultsThe diameter of matrix was 20–40 nm. The K_m value of the immobilized LXYL-P1-2 catalyzing XDT (0.145 mM) was lower than that of the free enzyme (0.452 mM), and the k_cat/K_m value of immobilized enzyme (12.952 mM s⁻¹) was higher than the free form (8.622 mM s⁻¹). The immobilized form maintained 50% of its original activity after 15 cycles of reuse. In addition, the stability of immobilized LXYL-P1-2, maintained 84.67% of its initial activity, improved in comparison with free form after 30 d storage at 4°C.ConclusionsThis investigation not only provides an effective procedure for biocatalytic production of DT, but also gives an insight into the application of magnetic material immobilization technology.How to citeZou S, Chen TJ, Li DY, et al. LXYL-P1-2 immobilized on magnetic nanoparticles and its potential application in paclitaxel production. Electron J Biotechnol 2021;50.https://doi.org/10.1016/j.ejbt.2020.12.005     

An approach for selecting and using a method of inter-coder reliability in information management research

Qualitative researchers in information management research often need to evaluate inter-coder reliability (ICR) to test the trustworthiness of their content analysis. A suitable method of evaluating ICR enables researchers to rigorously assess the degree of agreement among two or more independent qualitative coders. This allows researchers to identify mistakes in the content analysis before the codes are used in developing and testing a theory or a measurement model and avoid any associated time, effort and financial cost. Different methods have been proposed, but little guidance is available on which approach to evaluating ICR should be used. In this paper, we review and compare leading ICR methods that are suitable for qualitative information management research. We propose an approach for selecting and using an ICR method, supported by an illustrative example. The five steps in our proposed approach include: selecting an ICR method based on its characteristics and requirements of a project; developing a coding scheme; selecting and training independent coders; calculating the ICR coefficient and resolving discrepancies; and reporting the process of evaluating ICR and its results.     

可扩展大屏幕高分辨率并行显示系统的构建及其在地学中的应用

可扩展大屏幕高分辨率并行显示系统的构建,包括硬件环境、软件环境与软件技术、图形校正与颜色校正.基于SAGE和VizRoll大屏幕显示技术,利用PC-cluster及LCD构建了一个可扩展4×5高分辨率并行显示阵列,并实现了高分辨率并行显示系统在地学可视化中的几个典型应用.     

复格拉斯曼流形G(2,5)中的全纯2球

利用调和序列和活动标架研究了复格拉斯曼流形G(2,5)中线性满的全纯2球.利用SU(2)的不可约酉表示构造了G(2,5)中的一些齐性全纯2球.在U(5)等价意义下确定常高斯曲率为2/3和4/3的所有线性满的退化全纯2球.最后证明在某一特定条件下常高斯曲率为4/3的非退化的全纯2球一定是U(5)等价的.     

Rapid fabrication of a microdevice with concave microwells and its application in embryoid body formation

Here, we report a novel method for the fabrication of polydimethylsiloxane microdevices with complicated 3-D structures, such as concave and crater shapes, using an easily machined polymethyl methacrylate mold combined with a one-step molding process. The procedure presented here enables rapid preparation of complex 3-D microstructures varying in shape and dimensions. To regulate embryoid body (EB) formation, we fabricated a microfluidic device with an array of concave microwells and found that EBs growing in microwells maintained their shape, viability, and a high degree of homogeneity. We believe that this novel method provides an alternative for rapid prototyping, especially in fabricating devices with curved 3-D microstructures.     

The evolving relations between government agencies of innovation policymaking in emerging economies: A policy network approach and its application to the Chinese case

Literature on innovation policy reveals little of how relations between government agencies as policymakers evolve. Taking the policy network approach, this paper investigates three mechanisms underlining the evolution of inter-government agency relations in emerging economies – policy agenda, power concentration and heterogeneity dependence, and applies them to the analysis of the evolution of innovation policymaking in China. Operationally, the paper proposes a social network analysis (SNA)-based method to quantitatively study China’s innovation policy network, which consists of 463 innovation policy documents formulated by its central government ministries between 1980 and 2011. The findings show that the formal policy network for innovation has been not only sustained through the intervention of policy agendas but also self-organized because of policy network’s nature of power concentration and heterogeneity dependence. The presence of such mixed mechanisms in China’s innovation policy network’s evolution differs from the findings from industrialized countries where self-organization plays a central role. This work advances our theoretical understanding of the evolution of innovation policy network and has implications for innovation policymaking in emerging economies.     

Scaffold fabrication in a perfusion culture microchamber array chip by O(2) plasma bonding of poly(dimethylsiloxane) protected by a physical mask

Extracellular matrix (ECM) proteins are required for cell culture. In this paper, we report the use of O(2) plasma bonding to fabricate a perfusion culture microchamber array chip with identical-size ECM spots in the isolated microchambers. The chip was fabricated by assembly of two poly(dimethylsiloxane) (PDMS) layers, a microfluidic network layer, and an ECM array layer, which were aligned and then bonded by O(2) plasma oxidation with protection of the ECM microarray with a physical mask made from PDMS. We successfully cultivated Chinese hamster ovary K1 cells in the microchambers with fibronectin. In the fibronectin microchambers, the cells adhered and extended after 12 h of static culture and then grew over the course of 1 d of perfusion culture.     

Age-Related Changes in Soluble Vascular Endothelial Growth Factor Receptor 1 (sVEGFR1) and Receptor 2 (sVEGFR2) in Healthy Japanese Subjects

We measured serum soluble vascular endothelial growth factor receptor 1 (sVEGFR1) and receptor 2 (sVEGFR2) levels in healthy Japanese individuals in order to establish a reference value using a specific ELISA. Significant differences were observed in serum sVEGFR1 and sVEGFR2 levels between children and adults. To demonstrate the usefulness of the reference value for children, we measured serum sVEGFR1 and sVEGFR2 levels in children with diarrhea positive (D+) hemolytic uremic syndrome (HUS) as a preliminary study. Serum sVEGFR2 levels in children with HUS were markedly higher than those in healthy children from the onset of D + HUS. The reference value for healthy children in the present study will allow normal and pathological conditions to be discriminated from each other in future study     

无线射频识别技术(RFID)及其在物联网中的应用

随着物联网知识的普及,以及其技术的广泛推广应用,物联网被越来越多的人所关注。本文介绍了物联网及其关键技术RFID,并结合RFID在物联网的实际应用,并对其未来的发展作出了展望。     

Standardization of a dilution method for cyclosporin (C2) estimation in renal transplant patients

Accurate monitoring of blood cyclosporin C2 levels is vital to prevent over immunosuppression and acute renal toxicity in patients who receive organ transplant. The matrix used to dilute patients’ C2 samples prior to the assay affected the final measured values. Hence there was a need to develop a method of dilution that would accurately estimate C2 levels when cyclosporin levels were beyond the calibration range of the method employed. Whole blood, cyclosporin free hemolysate and cell and protein free supernatant obtained after pretreatment of normal blood were used to dilute patients’ C2 samples. C2 was measured in 188 patients using the supernatant method of dilution. C2 was correlated with Co and dose of cyclosporin received by the patient. The use of cell and protein free supernatant obtained after pretreatment of normal blood as a C2 diluent detected higher levels of C2 in the sample. Measured C2 correlated significantly with Co and the cyclosporin dose received by the patient. The uniformly aqueous cell and protein free supernatant ensures uniform dilution of the patients’ C2 sample and measures higher cyclosporin levels.     

EAD与ISAD(G)的映射关系及其在中文档案著录中的应用

EAD是网络环境下档案管理、图书馆、博物馆处理档案与手稿资料最常用的元数据。本文简要介绍了EAD的发展历程，详细阐述了EAD与ISAD（G）（《国际档案著录标准（总则）》）相关元素之间的映射关系，并举例说明了EAD在中文档案著录中的应用情况，旨在为EAD在中文档案领域的推广应用以及EAD与其他它数据格式之间的转化提供一定的借鉴与参考。