Plasma and erythrocyte magnesium levels in patients with preeclampsia/eclampsia

Plasma and erythrocyte magnesium levels were estimated in preeclampsia and eclampsia. Mean plasma as well as erythrocyte magnesium concentrations were found to be significantly lowered than the controls. Hypomagnesemia was directly related with the severity of the disease. Plasma calcium concentration however, was not significantly altered.     

Evaluation of the changes in serum iron levels in pre-eclampsia

Serum iron levels were studied in 50 patients with pre-eclampsia and the results were compared with 50 control cases. Their serum iron levels were found to be higher than the controls. Increase in serum iron was directly proportional to the increased levels of uric acid, urea and creatinine. Mean reticulocyte counts, plasma free haemoglobin and unconjugated bilirubin levels were also higher in these patients. It is suggested that haemolysis may be a major contributory factor for the increased levels of serum iron in pre-eclampsia.     

A preliminary study of protein thiols and serum cholinesterase in assisted reproduction

In this study we sought to investigate the levels of serum protein thiols and cholinesterase levels before and after intrauterine insemination (IUI).We observed 68% patients showed a decrease in protein thiols and 63% showed a decrease in serum cholinesterase levels after insemination as compared to their respective pre procedure levels. The fall in thiols was statistically significant (p=0.021) indicating there is increased oxidative stress after the procedure. However, we could not comment on any reason for the fall in cholinesterase. Whether the changes in above parameters may have some implication on the overall success rate of IUI is yet to be ascertained.     

葛根汤治疗早发型重度子痫前期的临床疗效研究

目的:探讨葛根汤治疗重度子痫前期的临床疗效。方法:对广西中医药大学第一附属医院2013年6月至2016年1月收治的早发型重度子痫前期病人80例,采用随机数字表法随机分为A(研究组)和B(对照组)。对照组常规用解痉药硫酸镁、降压药硝苯地平治疗,研究组除常规治疗,加用葛根汤治疗。观察两组治疗后平均动脉压、24h尿蛋白量、脐动脉血流阻力、全血粘度、D-二聚体;终止妊娠时新生儿体重、新生儿窒息例数及延长孕龄时间;两组母儿并发症(包括:胎盘早剥、肝肾功能损害、心衰肺水肿、脑血管意外、DIC、胎儿窘迫等)例数等指标。结果:A组治疗后平均动脉压、24h尿蛋白量、脐动脉血流阻力、全血粘度、D-二聚体均明显低于B组,差异均具有统计学意义(P0.01);A组胎儿窘迫例数比B组少(P0.05),A组治疗后延长孕龄时间比B组长(P0.01),差异均具有统计学意义。A组新生儿体重比B组大,新生儿窒息例数比B组少,但差异均无统计学意义(P0.05)。结论:葛根汤治疗早发型重度子痫前期临床疗效确切,值得推广。     

A study of serum zinc, selenium and copper levels in carcinoma of esophagus patients

The association of serum trace elements like selenium, zinc and copper has been found in different types of cancer. This study was conducted to see the serum level of these three trace elements in cancer esophagus patients. Biopsy confirmed cancer esophagus, 24 patients (12 males, 12 females, mean age 54.5±11.65 year with 23 healthy subjects (16 males, 7 females, mean age 44 ±13.82 years) were included in this study. Both control and study group patients were of same socio-economic status and dietary habits. Serum zinc and copper level were estimated using standard absorption spectrometer technique and serum selenium by Hydride generation method. We observed significant low serum levels of zinc and selenium while high level of serum copper in carcinoma esophagus patients, as compared with normal healthy controls. This shows an association of serum selenium zinc and copper with cancer esophagus.     

高原地区30例产前子痫的抢救及护理

产前子痫是妊高征最严重的阶段，发生在妊娠晚期或临产前的阵发性抽搐、昏迷，是围产儿及孕产妇死亡的主要原因。为此护理人员对这一病例必须高度重视，掌握子痫病人的有效抢救方法和护理技能是非常重要的。     

A study of serum lipid profile part-1: Establishment of normal reference values of serum lipid levels in healthy vegetarian population of Gujarat

Fasting samples of 1329 apparently healthy vegetarian Gujarati population were tested for total cholesterol, triglycerides and three major fractions of lipoproteins, i.e. high density lipoproteins, low density lipoproteins and very low density lipoproteins. All the values showed marked increase with the age. Except for serum triglycerides, values differ in males and females in the age group of above 45 years. Compared to Northern Indian population low density lipoprotein and high density lipoprotein values were higher, but values of triglycerides and very low density lipoproteins were lower. There is no significant difference in total cholesterol values. Compared to Southern Indian population low density lipoprotein and very low density lipoprotein values were higher but values of triglycerides, total cholesterol and high density lipoprotein were lower. All serum lipid values were significantly lower than the Westem population. The range of values for both the sexes is presented for different age groups.     

Correlative study of fluoride content in urine,serum and urinary calculi

Fluoride content was measured in 100 urinary stones retrieved by open surgery of stone formers admitted at PGIMS Rohtak and their respective urine and serum and compared with those of healthy individuals. The concentration of fluoride was also measured in the sources of drinking water of these stone formers. The concentration of fluoride was definitely significantly higher in serum (p>0.01) and highly significantly higher in urine (p>−0.001) of stone formers compared to those of healthy individuals. The content of oxalate in serum and 24 h urine of the stone formers was also measured, which was increased significantly (p<0.005 and p<0.001) compared to healthy individuals. The concentration of fluoride was probably significantly higher in drinking water of these stone formers than the normal ones. There was a positive correlation between the content of fluoride of urinary stones and urine of stone patients (r=.88); stone and serum (r=.62); drinking water and stone (r=.85) and their urine and serum (r=.54); urine and drinking water (r=.83) and serum and water (r=.51). These results indicate a definite role of fluoride in urinary stone formation.     

两种血清铁试剂的对比研究及偏倚评估

目的 在日立7600型全自动生化分析仪上以和光、朗道试剂进行患者标本血清铁测定的对比研究和偏倚评估,其中朗道试剂用德国罗氏c.f.a.s校准品校准,对患者标本分别测定.方法 依据美国国家临床实验室标准协会(NCCLS)EP9-A文件,每天取临床标本8 份,分别用两个厂家试剂测定标本血清铁,共测定5天,记录检验结果,对两种试剂进行偏倚评估.结果 在进行患者新鲜血清标本血清铁测定时,两种试剂测定结果的预期相对偏倚为1.50%,两种试剂测定的浓度结果的线性回归方程为Y=0.218030X+0.971541,相关系数R2=0.99907,在方法的线性范围内可以被接受,实验室数据的配对t检验结果显示,P＞0.05差异无统计学意义;测定不同的质控品,不同厂家试剂及应用不同校准品,测定结果相对偏倚最大为4.85%.结论 和光及朗道两种试剂在测定患者标本血清铁时,测定结果的相对偏倚在线性范围内能被接受,在测定不同的质控品时,其相对偏倚不大(＜5%).由此可见,两种试剂都可作为任意检测的试剂,但当实验室内同一项目存在两种或两种以上分析试剂检测时,需对其进行对比分析和偏倚评估,对这些项目在分析系统间的偏倚有了准确的评价管理依据,才能保证检测结果的准确稳定.     

医用镁合金材料的可降解性能研究初探

镁合金因满足生物材料力学的性能要求,具有良好的生物相容性和可降解性等优势,已成为最具发展潜力的一种生物医用可降解材料。然而,镁合金在具备上述优势条件的同时,亦存在着一个突出问题,即如何控制镁合金的降解速度。文章从高纯镁合金和新合金的开发、镁合金的热处理、快速凝固技术和微弧氧化技术四个方面对近年来镁合金腐蚀速度控制方面的研究工作进行了总结,为改善镁合金可降解性能的相关研究提供参考。     

国家科技攻关项目组织实施模式的探讨与实践——以"镁化合物功能材料的开发利用及产业化"项目为例

北京化工大学承担“十五”国家科技攻关计划重点项目“镁化合物功能材料的开发利用及产业化”。该项目在组织及实施过程中,充分融入了可持续发展理念;强调了项目的多重目标导向性;加强了技术攻关主线上的标准化、检测、知识产权保护等配套软环境维护;突出企业主体地位,通过多种方式促进技术成果的产业化和商品化推广;注重项目管理模式的创新,取得了良好的社会效益和经济效益,其产品在应对欧盟绿色技术壁垒的过程中发挥了重要作用。     

Modified method for determination of serum beta-glucuronidase: A comparative study using P-nitrophenyl glucuronide and phenolphthalein glucuronide as substrate in gastrointestinal tract carcinomas

Serum beta-glucuronidase activity was estimated by our modified method using two substrates phenolphthalein glucuronide and p-nitrophenyl glucoronide in 49 healthy subjects and 94 patients with gastrointestinal tract (GIT) carcinoma. The correlation coefficient using the two substrates was found to be r=0.8383. The method of Gabor Szasz was modified wherein the incubation time was decreased from 5 hours to 2 hours and the incubation temperature was increased from 25°C to 37°C. The increase in beta-glucuronidase activity in GIT carcinoma appears to be a good biochemical marker in patients with such type of carcinomas, a finding not reported in literature to-date. The modified quantitative method used for estimation of beta-glucuronidase is reliable, accurate, simple and rapid.     

A test strip for the estimation of urea in serum

We have developed a biostrip for determination of urea in serum. The test strip is based on enzymatic assay where urease has been immobilized on the chromatographic paper along with chromogen, phenol red. The chromogen is easily soluble in water and does not require other components for the color change. Serum urea reacts with urease and water to liberate ammonia and carbon dioxide. The liberated ammonia changes the pH of the reaction medium, which is monitored by the chromogen phenol red. A single step working reagent strip has been developed and the reaction is completed within 50 seconds at room temperature. With this test strip urea concentration is measured in serum as low as 0.15 g/L. The speed and convenience of determining urea in serum by this strip instantly makes it well suited for individuals, physicians and emergency centres.     

Alterations of serum cholesterol and serum lipoprotein in breast cancer of women

Fasting blood sample of 50 normal subjects (control) and 100 patients of breast cancer were investigated for serum total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol, very low density lipoprotein, high density lipoprotein cholesterol:low density lipoprotein cholesterol ratio and total cholesterol:high density lipoprotein cholesterol ratio during breast cancer of women. Five cancer stages, types, age groups, parity and menopausal status were undertaken for the study. It was observed that there was a significant rise in serum total cholesterol and low density lipoprotein cholesterol whereas high density lipoprotein cholesterol and very low density lipoprotein cholesterol were not significant. The ratio of high density lipoprotein cholesterol:low density lipoprotein cholesterol and total cholesterol:high density lipoprotein cholesterol values increased significantly in breast cancer patients.     

Comparative study of serum myoglobin and creatine kinase MB isoenzyme in the detection of acute myocardial infarction

Serum creatine kinase MB isoenzyme (CKMB) and myoglobin have been studied in 35 cases with myocardial infarction. Increased values for both serum CKMB and myoglobin have been found in all the patients in the second sample collected 4 hr. after admission while in 22 patients in the first sample collected immediately after admission. Thus, the present study shows a good correlation between serum CKMB and myoglobin and therefore, suggests the possibility of using the serum myoglobin estimation in early detection of myocardial infarction either alone or in combination with the serum CKMB.     

镁合金在汽车上的应用现状和前景分析

随着全球范围内的能源紧缺以及各国政府对环境保护的日益重视,汽车(尤其是轿车)的轻量化已成为世界范围内汽车工业发展的必然趋势。在汽车车身结构上使用铝、镁可有效减轻汽车重量,环保上更节油和降低排放,以轻金属镁来取代钢更适应于汽车工业的特殊需要。介绍了镁合金在汽车上的应用情况和发展趋势。     

镁合金在汽车上的应用现状和前景分析

随着全球范围内的能源紧缺以及各国政府对环境保护的日益重视，汽车（尤其是轿车）的轻量化已成为世界范围内汽车工业发展的必然趋势。在汽车车身结构上使用铝、铗可有效减轻汽车重量，环保上更节油和降低排放，以轻金属铗来取代钢更适应于汽车工业的特殊需要。介绍了镁合金在汽车上的应用情况和发展趋势。