A novel reduction of diketones with i-RMgBr catalyzed by Cp2TiCl2 and deoxygenation of sulfoxides by Cp2TiCl2/Al system

α-diketones and β-diketones react with Grignard reagents in the presence of a catalytic amount of Cp2TiCl2 to yield α-ketols and corresponding ketones respectively. Sulfoxides can be deoxygenated by Cp2TiCl2/Al system. The possible mechanisms are also discussed.     

Science Letters:A novel reduction of diketones with i-RMgBr catalyzed by Cp_2TiCl_2 and deoxygenation of sulfoxides by Cp_2TiCl_2/Al system

α-diketones and β-diketones react with Grignard reagents in the presence of a catalytic amount of Cp2TiCl2 to yield α-ketols and corresponding ketones respectively. Sulfoxides can be deoxygenated by Cp2TiCl2/Al system. The possible mechanisms are also discussed.     

A novel reduction of diketones with i-RMgBr catalyzed by Cp<Subscript>2</Subscript>TiCl<Subscript>2</Subscript> and deoxygenation of sulfoxides by Cp<Subscript>2</Subscript>TiCl<Subscript>2</Subscript>/Al system

α-diketones and β-diketones react with Grignard reagents in the presence of a catalytic amount of Cp₂TiCl₂ to yield α-ketols and corresponding ketones respectively. Sulfoxides can be deoxygenated by Cp₂TiCl₂/Al system. The possible mechanisms are also discussed. Project (No. 20072033) supported by the National Natural Science Foundation of China and the Specialized Research Fund for the Doctoral Program of Higher Education Ministry, China