Heterogeneity of patenting activity and its implications for scientific research

The increasing commercialization of university discoveries has initiated a controversy on the impact for scientific research. It has been argued that an increasing orientation towards commercialization may have a negative impact on more fundamental research efforts in science. Several scholars have therefore analyzed the relationship between publication and patenting activity of university researchers, and most articles report positive correlations between patenting and publishing activities of scientists. However, previous studies do not account for heterogeneity of patenting activities. This paper explores the incidence of patenting and publishing of scientists distinguishing between corporate patents and patents assigned to non-profit organizations for a large sample of professors active in Germany. While patents assigned to non-profit organizations (incl. individual ownership of the professors themselves) complement publication quantity and quality, patents assigned to corporations are negatively related to quantity and quality of publication output.     

Bottom-up versus top-down policies towards the commercialization of university intellectual property

What national policies are most efficient in promoting the commercialization of university-generated knowledge? We address this question by characterizing and evaluating the policy pursued in Sweden and the US, two countries that put a great deal of resources into university R&D, but follow very different models for commercialization. Despite a leading academic record, there is an impression of laggard rates of commercialization of academic research results in Sweden. Although there exist no micro data to evaluate this impression, we argue that it is likely to be true in part due to the top-down nature of Swedish policies aimed at commercializing these innovations as well as an academic environment that discourages academics from actively participating in the commercialization of their ideas. This sits in stark contrast to a US institutional setting characterized by competition between universities for research funds and research personnel, which in turn has led to significant academic freedoms to interact with industry, including significant involvement in new firms.     

The impact of firm participation in R&D programmes on R&D partnerships

R&D subsidies designed to encourage innovation efforts by firms may have intended and unintended effects on the way they organize their innovation process. We present empirical evidence on how R&D subsidies affect firms’ R&D cooperation strategies. In particular, we investigate whether receiving public R&D subsidies affect the probability that a firm will set up an R&D partnership with a public research organization (PRO), or with other firms. Our main findings are: (i) public support significantly increases the chances that a firm will cooperate with a PRO, and (ii) public support also increases the likelihood that a firm will establish private partnerships, but to a smaller extent and only when firms have intangible knowledge assets. These results suggest that public R&D programmes trigger a behavioural change in firms’ R&D partnerships, alleviating barriers to cooperation.     

Knowledge protection strategies of multinational firms—A cross-country comparison

International knowledge spillovers, especially through multinational companies (MNCs), have recently been a major topic of discussion among academics and practitioners. Most research in this field focuses on knowledge sharing activities of MNC subsidiaries. Relatively little is known about their capabilities for protecting valuable knowledge from spilling over to host country competitors. We extend this stream of research by investigating both formal protection strategies (e.g. patenting) as well as strategic ones (secrecy, lead time, complex design). We conceptualize the breadth of firm's knowledge protection strategies and relate it to the particular situation of MNC subsidiaries. Moreover, we argue that their approaches differ with regard to host country challenges and opportunities. We address these issues empirically, based on a harmonized survey of innovation activities of more than 1800 firms located in Portugal and Germany. We find evidence that MNCs prefer broader sets of knowledge protection strategies in a host country with fewer opportunities for knowledge sourcing (Portugal). In Germany, though, they opt for narrower sets of knowledge protection strategies if they invest in innovation activities themselves. We deduce that these results are due to a need for reciprocity in knowledge exchanges to benefit fully from promising host country knowledge flows.     

The creation of spin-off firms at public research institutions: Managerial and policy implications

We consider the managerial and policy implications of the rise of spin-offs at public research institutions (PRIs), based on a knowledge-based view (KBV) of the firm. This framework highlights the importance of knowledge in the creation and development of spin-offs. We argue that in order to understand the development of spin-offs, researchers should focus on “knowledge gaps” these new ventures encounter. Knowledge gaps can occur at different levels of aggregation, including the PRI, spin-off, team, individual, incubator, and at different stages of spin-off development. Based on this framework, we synthesize findings from previous studies and papers in the special issue and offer some suggestions for additional research on spin-offs from PRIs.     

Gaining from interactions with universities: Multiple methods for nurturing absorptive capacity

This paper examines the various methods through which firms benefit from interactions with universities, arguing that such benefits are instrumental in nurturing the multiple facets of a firm's absorptive capacity. We bring together data collected from a survey of UK firms that collaborated with universities, and firm-level data on past partnerships with universities. The results show that benefits from interactions with universities are multifaceted, including enhancement of the firm's explorative and exploitative capabilities. Results also indicate that firms’ R&D commitments, geographical proximity to and research quality of university partners have a distinct impact on the different types of benefits from interactions with universities. We find geographical proximity is crucial for assessing problem-solving as an important benefit, while interactions with top quality universities have a positive influence on the benefits associated with firms’ downstream activities. We discuss the implications of these findings for research and policy.     

The impact of public basic research on industrial innovation: Evidence from the pharmaceutical industry

While most economists believe that public scientific research fuels industry innovation and economic growth, systematic evidence supporting this relationship is surprisingly limited. In a recent study, Acemoglu and Linn (2004) identified market size as a significant driver of drug innovation in the pharmaceutical industry, but they did not find any evidence supporting science-driven innovation from publicly funded research. This paper uses new data on biomedical research investments by the U.S. National Institutes of Health (NIH) to examine the contribution of public research to pharmaceutical innovation. The empirical analysis finds that both market size and NIH funded basic research have economically and statistically significant effects on the entry of new drugs with the contribution of public basic research coming in the earliest stage of pharmaceutical drug discovery. The analysis also finds a positive return to public investment in basic biomedical research.     

Limits to database protection: Fair use and scientific research exemptions

A trend running diametrically opposed to the expansion of Intellectual Property Rights (IPR) is the increasing awareness that dominant positions sustained by IPR may be mitigated through exemptions and statutory or compulsory licences. It is argued that there are compelling economic reasons to protect valuable assets that are prone to copying, but that there are equally compelling reasons to limit monopolistic claims and stimulate cross-licensing practices. Compulsory licensing may serve as a stimulus to the bargaining process with private parties and research institutions alike. Another important category of information is public sector information. Access to information has become a concern and the European Commission has followed up on its Green Paper on Public Sector Information in the Information Society, with a Directive implementing its vision on affordable access for all and exploitation potential. The right of access to information may be enforced through the European Convention on Human Rights. It not only guarantees the freedom of speech, it also recognises the freedom to receive information.     

What exactly are technological regimes?: Intra-industry heterogeneity in the organization of innovation activities

This empirical study analyzes the patterns of innovation within and across industries using firm-level survey data from Finland and Denmark. The theoretical starting point is evolutionary theory with its premise that firms in different technological regimes pursue different paths to innovation. Similar modes of behaviour are found in the two datasets, and they closely correspond to those found in earlier studies. Contrary to prevailing assumptions, however, the results show that industries are not at all uniform in terms of how firms innovate; in almost all four- or five-digit NACE industries, three or more different modes of innovation can be identified. This suggests that firms’ strategic differentiation or local search activities overcome pressures in the technological environment towards homogenous behaviour, at least in the short term.     

Diversification and hybridization in firm knowledge bases in nanotechnologies

The paper investigates the linkages between the characteristics of technologies and the structure of a firms’ knowledge base. Nanotechnologies have been defined as converging technologies that operate at the nanoscale, and which require integration to fulfill their economic promises. Based on a worldwide database of nanofirms, the paper analyses the degree of convergence and the convergence mechanisms within firms. It argues that the degree of convergence in a firm's nano-knowledge base is relatively independent from the size of the firm's nano-knowledge base. However, while firms with small nano-knowledge bases tend to exploit convergence in each of their patents/publications, firms with large nano-knowledge bases tend to separate their nano-R&D activities in the different established fields and achieve diversity through the juxtaposition of the output of these independent activities.     

What hampers innovation? Revealed barriers versus deterring barriers

Innovating firms are likely to face several challenges and experience different types of barriers. In this paper we argue that it is necessary to distinguish between two kinds of barriers to innovation. The first corresponds to what we describe as revealed barriers and reflects the degree of difficulty of the innovation process and the learning experience consequent on the firm engaging in innovation activity. The second type of impediment, which we label deterring barriers, encompasses the obstacles that prevent firms from committing to innovation. We use data from the 4th UK Community Innovation Survey (CIS4) to investigate the relationship between firms’ engagement in innovation and their assessment of the barriers to innovation. We show that the relationship is curvilinear in the case of costs and market barriers. These results have important implications for innovation policy and innovation management.     

Innovation and firm value: An investigation of the changing role of patents, 1985–2007

This paper examines how the relationship between firm value and patent-based indicators of inventive activity has changed over time. We use data from more than 33,000 mergers and acquisitions deals between 1985 and 2007, and distinguish between American (USPTO) and European (EPO) patents. Our results indicate that over time EPO patents have become the dominant indicator of innovative activity, while USPTO patents have no effect on firm value near the end of the sample period. The results are robust to controlling for citations and are especially strong for small firms, for firms operating in the drug and chemical industries, and when target and acquiring firms operate in different industries or countries.     

China's innovation system reform and growing industry and science linkages

In this paper, linkages of S&T activities between industry and science are statistically investigated, based on a firm level dataset from an S&T survey by the National Bureau of Statistics (NBS) of the PRC of about 22,000 manufacturing firms. During the transition period of China's innovation system from 1996 to 2002, firms’ S&T outsourcing activities increased significantly. Econometrics analysis reveals that (1) “absorptive capacity” for S&T outsourcing becomes important over time, (2) innovation system reforms for more market-based competition work for better incentive scheme for innovation though S&T linkage activities and (3) government funding of S&T induces more S&T linkages.     

Distance to the frontier and the perception of innovation barriers across European countries

Barriers to innovation have mainly been studied in a single country context. This paper studies differences in the perception of innovation barriers between innovative and non-innovative firms for 18 EU countries. The countries are grouped by their distance to the technological frontier using Community Innovation Surveys for the years 2002–2004 and 2004–2006. The results show that knowledge barriers related to the availability of skilled labour, innovation partners and technological knowledge are more important for firms located in countries close to the frontier, while the opposite is true regarding the availability of external finance. Moreover, while the share of innovators decreases with the distance to the technological frontier, the share of firms not interested or in no need of innovation increases. This is consistent with the idea that as firms approach the technological frontier, they increasingly need to focus on the creation of own knowledge and the adoption of innovation-based growth strategies to stay competitive.     

Innovation and productivity in developing countries: A study of Argentine manufacturing firms’ behavior (1992-2001)

Following the methodology employed in studies for industrialized countries and using panel data from innovation surveys in Argentina with information for 1992-2001, this paper contributes to the nascent literature that analyzes the determinants of innovative inputs and outputs and their impacts on manufacturing firms’ productivity in developing countries. The econometric results show that in house R&D and technology acquisition expenditures have positive payoffs in terms of enhanced probability of introducing new products and/or processes to the market. In turn, innovators attain higher productivity levels than non-innovators. The results also show that large firms have a higher probability of engaging in innovation activities and of becoming innovators.     

从高校角度谈技术转移中的知识产权保护

技术转移是高校科技成果转化为生产力的基本途径和方法。为了加强高校在技术转移中知识产权保护,避免和防止四技服务合同中知识产权归属不明确现象,对在技术转移过程中产生的技术成果应依照法律进行知识产权自我保护,正确选择技术成果保护的方式和时机。     

Assessing the impact of organizational practices on the relative productivity of university technology transfer offices: an exploratory study

We present quantitative and qualitative evidence on the relative productivity of university technology transfer offices (TTOs). Our empirical results suggest that TTO activity is characterized by constant returns to scale and that environmental and institutional factors explain some of the variation in performance. Productivity may also depend on organizational practices. Unfortunately, there are no quantitative measures available on such practices, so we rely on inductive, qualitative methods to identify them. Based on 55 interviews of 98 entrepreneurs, scientists, and administrators at five research universities, we conclude that the most critical organizational factors are faculty reward systems, TTO staffing/compensation practices, and cultural barriers between universities and firms.     

Technology, security, and policy implications of future transatlantic partnerships in space: Lessons from Galileo

Policy makers seek to identify an institutional framework that facilitates the commercialization of publicly funded R&D, while simultaneously addressing innovation market failure. In the space industry, the formation of such a framework is complicated by national security considerations and the fact that numerous sovereign nations are often included in the commercialization process. This paper analyses how multi-public partnerships with industry can promote commercially viable space programs, resolve market failures, and address transatlantic security concerns. The benefits and policy implications of the formation of such transatlantic multi-public-private partnerships (TMP³) are illustrated based on a case study of the design of a major European public-private project in the space industry: the Galileo space-based navigation system.     

Sources of spillovers for imitation and innovation

We estimate the effect of R&D spillovers on sales realized by products new to the firm (imitation) and new to the market (innovation). It turns out that spillovers from rivals lead to more imitation, while input from customers and research institutions enhance original innovation.