The dynamics of R&D network in the IT industry

In this paper, we provide an empirical analysis of evolving networks of successful R&D collaborations in the IT industry (consisting of firms that obtained patents in the technological category of computers and communication) in the U.S. between 1985 and 1995. We first show that the R&D network has become more extensive, more clustered, and more unequal in the sense that ‘stars’ have emerged in the network. We then analyze the effect of the existing network structure in the process of new R&D collaboration formation. We control for unobserved similarities among firms based on the community structures within the network that the algorithm developed by Girvan and Newman (2004) identifies and find a significant cyclic closure and preferential-attachment effect.     

Dual market structures and the likelihood of repeated ties - evidence from pharmaceutical biotechnology

This paper analyses the role of repeated ties in the high-tech pharmaceutical biotechnology industry, a sector that is characterized by a strong dual market structure. Our most important finding is that previous ties in pairs of large pharmaceutical companies and small biotechnology firms have a negative effect on their subsequent partnering. An explanation for this result is found in the context of understanding the specifics of large-small coalitions in a high-tech dual market structure. Unlike what is known about repeated ties in many other industries, this high-tech dual market structure indicates that R&D partnerships between a small number of very large companies and a large group of dependent, small firms are not characterized by mutual dependence, similarity, or equality.     

Marketing/R&D integration in the pharmaceutical industry

Integrating marketing and R&D inputs is one of the fundamental challenges in managing innovation. In the pharmaceutical industry, considering its reputed ‘technology push’ model of innovation, the challenge of integrating marketing and R&D could hardly be greater. Thus, the recent trend among pharmaceutical firms of implementing Marketing/R&D integrating mechanisms calls for upgrading our conceptualization of the innovation process in this industry. It also raises important questions regarding Marketing's contribution in new product development, and how to organize to assure that contribution is leveraged. We use the case of a pharmaceutical firm which recently implemented Marketing/R&D integrating mechanisms to examine Marketing's new roles. We find that the extreme conditions surrounding innovation in the pharmaceutical industry, notably the need to cope with Knightean uncertainty, highlight important contributions of Marketing input in R&D that deserve more attention. We suggest that Marketing's most important contribution under these conditions lies in ‘not getting it wrong’ rather than ‘getting it right,’ in setting minimum criteria in project evaluations rather than definite targets, and in refocusing the attention of R&D staff through the very process of providing this input. Given the value of these contributions, modern pharmaceutical firms would indeed be ill advised to think of drug discovery as merely a linear process. Drug development has become an interactive process where the timing, type and impact of Marketing involvement is balanced and managed via certain organizational mechanisms throughout the R&D process, which is an iterative one.     

MNCs’ offshore R&D networks in host country's regional innovation system: The case of Taiwan-based firms in China

China has become a hot spot of R&D internationalization and a growing number of Taiwan-based firms have indeed set up R&D units in China. Taking into account China's substantial regional variations in economic development, innovation capacity, and knowledge productivity, such notions as regional innovation system (RIS) and local innovative milieu may become more relevant to the study on relationships between China and its inward R&D internationalization. Therefore, the key issue for this paper is what locational advantages of an RIS within a host country affect the network linkages and networking strategy of multinational corporations’ (MNCs’) offshore R&D units. The paper aims to enrich the current understanding of R&D internationalization in several ways. First, the paper attempts to examine the R&D networking underlying R&D internationalization by Taiwan-based firms in China, with particular reference to the sub-national level inside China. Second, the paper tries to establish a link between the literature of R&D internationalization and that of RIS, with a modified version of Dunning's eclectic paradigm. Efforts are made to map the relationship between foreign subsidiaries’ local R&D networks and their host RISs inside China. Third, the paper takes advantage of a government databank to adopt a quantitative approach, the Seemingly Unrelated Bivariate Probit Regression model, with foreign subsidiaries as the unit of analysis, to highlight the role played by some aspects of the RIS in determining the local R&D networking of Taiwanese subsidiaries in China. Our evident shows that MNCs’ offshore R&D units that purse home-based technology exploitation strategy, the mainstream strategy regarding the developing host country, tend to be located in a host region with a strong knowledge application and exploitation subsystem, while an RIS with a strong knowledge generation and diffusion subsystem, within such a developing country as China, may induce MNCs’ local R&D units to pursue home-base technology augmenting strategy. On balance, not only the location choice but also the local R&D linkages of MNCs’ offshore subsidiaries are related to appropriate fits between the RIS and the subsidiaries’ innovation network inside the host country.     

Scientific foundation, organization structure, and performance of biotechnology and pharmaceutical firms

Technologists seek to advance practical applications of science while scientists seek to advance knowledge which may or may not have a practical application. Firms with a stronger basic science focus, e.g. biology and chemistry, seek to advance their scientific knowledge foundation in addition to developing and selling innovative products. Firms with a more highly applied science foundation (medicine, engineering, etc.) prioritize the development and sale of innovative products. Combining an Absorptive Capacity (AC) approach with Transaction Cost Economics (TCE) this study explores and explains how firms gain knowledge and perform given their scientific focus.Findings indicate that firms with a stronger basic science orientation are less profitable than firms with a stronger applied science orientation. Applied science firms had more acquisitions and cooperative organizations but both types of firms were more likely to acquire other firms in their quest to build knowledge stores rather than partner. Partnerships with universities were more prevalent among basic science firms than with applied science firms.     

Application of real options analysis for pharmaceutical R&D project valuation—Empirical results from a survey

Real options analysis was often recommended as an emerging valuation technique for high-risk investment projects. Former inter-sectoral surveys have drawn an ambivalent picture of real options usage in general. In addition, there is a lack of sector-specific investigations. In the following article the results of an in-depth analysis of collected empirical data regarding the application of this new tool in the pharmaceutical sector is presented by capturing the internal view from the pharmaceutical companies themselves and the external view from the health care departments of financial service firms. R&D stage specific modi of application, reasons for reluctance in the employment of real options and their assumed future prospects are elucidated.     

Effect of R&D programmes on the formation of university-industry-government networks: comparative analysis of Japanese R&D programmes

Japan has established several R&D programmes since the 1980s aimed at basic and fundamental R&D in response to the criticism of its free-riding on Western basic research. In some of these programmes, the linkages between university, industry and government have been a requirement for formation or selection of projects. In this paper, it is investigated how five Japanese R&D programmes promote inter-sectoral and inter-institutional networks. The result shows that the projects of the Next Generation Programme for pre-competitive research formed few but multiple university-industry-government linkages within each project by designing the complementary relationships among the participants. Linkages between private companies were not much formed except for the projects of the ERATO Programme, in which researchers temporarily leave their own institutes. The funds for more basic research was found to have little effect on the formation of networks within projects but do form the linkages outside the projects.     

关系网络、产权性质与研发投入

企业与客户和供应商的供应链关系构成了企业经营发展的重要关系网络,也是企业战略竞争优势的重要组成部分。本文研究了供应商和客户的集中程度对于企业研发投入的影响,使用中国A股主板上市公司2007—2014年的数据发现,供应商和客户的集中程度对于企业的研发投入强度具有显著为负的影响,预示着企业对于"敲竹杠"等机会主义行为的担忧抑制了其自身的资产专用性投资。本文还发现,相比于国有控股上市公司,供应商和客户对企业研发投入的负面影响在非国有控股的上市公司中体现地更为明显。本文的研究发现表明企业的供应链关系网络对其创新活动具有重要的影响。     

Shareholder returns and the exploration-exploitation dilemma: R&D announcements by biotechnology firms

We explore a financial returns dimension of the exploration-exploitation dilemma. Using 1277 R&D announcements by 178 listed bio-pharmaceutical firms, we examine whether investors are myopic along the continuum of exploration (patenting and preclinical trials) to exploitation (human clinical trials and NDA). We find that investors respond positively at every stage, but there are differences between small and large firms. For small firms exploration is favored, provided it is focused. For large firms, there is value in both exploration and exploitation. Projects which are part of an alliance are no more likely to generate abnormal returns. Policy implications are discussed.     

Institutionalizing end-user demand steering in agricultural R&D: Farmer levy funding of R&D in The Netherlands

The purpose of this paper is to critically examine the institutionalization of demand-driven modes of working in the R&D planning process and reveal possible weaknesses, through an analysis of a system of collective R&D funding by farmers. The findings indicate that, although end-users have the opportunity to raise issues that lead to R&D, queries are influenced by several actors in the R&D planning process in such a way that they do not adequately reflect farmers’ innovation needs. Conclusions are that more emphasis is required on joint demand articulation and involvement of end-users and other stakeholders in the innovation process, and on the institutional development of R&D funding organizations in order to adopt a more inclusive view on innovation.     

Technological similarity,post-acquisition R&D reorganization,and innovation performance in horizontal acquisitions

This paper aims to disentangle the mechanisms through which technological similarity between acquiring and acquired firms influences innovation in horizontal acquisitions. We develop a theoretical model that links technological similarity to: (i) two key aspects of post-acquisition reorganization of acquired R&D operations – the rationalization of the R&D operations and the replacement of the R&D top manager, and (ii) two intermediate effects that are closely associated with the post-acquisition innovation performance of the combined firm – improvements in R&D productivity and disruptions in R&D personnel. We rely on PLS techniques to test our theoretical model using detailed information on 31 horizontal acquisitions in high- and medium-tech industries. Our results indicate that in horizontal acquisitions, technological similarity negatively affects post-acquisition innovation performance and that this negative effect is not mediated by the reorganization of the acquired R&D operations. However, replacing the acquired firm's R&D top manager leads to R&D productivity improvements that positively affect innovation performance.     

Co-operative R&D: why and with whom?: An integrated framework of analysis

Firms use R&D partnerships to access knowledge and build global R&D networks. This article develops an integrated framework to examine the determinants of the choice of partners with which firms co-operate on R&D. This resource-based perspective underscores the interactions between three major questions: why co-operate, who does and with whom? It argues in particular that the choice of partners is dictated by the complementary resources which the latter command. The framework is then expanded to predict the relative efficiency of R&D co-operation with different partners, including suppliers, clients, rivals, academic institutions and foreign firms. The empirical analysis, which is based on responses to France’s version of the second European community innovation survey (CIS-2), strongly supports the overall framework of analysis.     

Creating advantage in peripheral regions: The role of publicly funded R&D centres

Regional investment in R&D, technological development and innovation is perceived as being strongly associated with productivity, growth and sustained international competitiveness. One policy instrument by which policy makers have attempted to create regional advantage has been the establishment of publicly funded research centres (PRCs). In this paper we develop a logic model for this type of regional intervention and examine the outputs and longer-term outcomes from a group of (18) publicly funded R&D centres. Our results suggest some positive regional impacts but also identify significant differences in terms of innovation, additionality and sustainability between university-based and company-based PRCs. University-based PRCs have higher levels of short-term additionality, demonstrate higher levels of organisational innovation but prove less sustainable. Company-based PRCs demonstrate more partial additionality in the short-term but ultimately prove more sustainable.     

The determinants of success of R&D projects: evidence from American-Israeli research alliances

Until 1997, a basic premise of Israeli R&D support programs had been the principle of neutrality—all eligible projects were funded. With a binding budget constraint, the government had to select the projects it funded and thus to depart from neutrality. An optimal departure would favor those projects that have less of a chance to succeed without support. In this paper, I examine the performance of government supported collaborative research projects. I find that size and organizational form affect the probability of technical success and duration to commercialization in a way that suggests departing from neutrality by preferring less established firms.     

Does R&D performance decline with firm size?—A re-examination in terms of elasticity

There have been many previous studies exploring the relationship between R&D performance and firm size; however, to our knowledge, this issue has never been examined in terms of R&D output elasticity. This paper therefore sets out to re-examine the relationship of the two variables using R&D output elasticity as a measure of R&D performance. A total of 126 manufacturing firms, listed on the Taiwan Stock Exchange over the period from 1994 to 2000, are taken as the analytical sample. One practical consideration for choosing these particular firms is the relative abundance of data available for the variables for a longitudinal investigation. The estimates suggest that there is an approximating ‘U-type’ relationship between R&D productivity and firm size. This finding suggests that both large and small firms have higher R&D productivity, and even when the sample is divided into the high-tech and traditional sectors, such a finding still holds. Therefore, in contrast to the prior studies, this study shows that size offers advantage in R&D performance.     

Measuring the change in R&D efficiency of the Japanese pharmaceutical industry

This paper presents a data envelopment analysis (DEA)/Malmquist index methodology for measuring the change in R&D efficiency at both firm and industry levels. Letting each of ten firms in each year be a separate decision-making unit, and employing one input and three outputs in a DEA case of R&D activity input-output lag, we measure “total factor R&D efficiency” change of Japanese pharmaceutical firms for decade 1983-1992 as defined by the period of R&D input. Decomposing Malmquist index into catch-up and frontier shift components and using “cumulative indices” proposed in this study, we evaluate R&D efficiency change for each firm and empirically show that R&D efficiency of Japanese pharmaceutical industry has almost monotonically gotten worse throughout the study decade.     

R&D支出、机构投资者与公司盈余管理

以制造业上市公司2006-2009年R&D支出数据为基础,本文采用LOGIT模型实证研究了我国机构投资者对公司通过削减R&D支出进行的盈余管理行为的影响。结果表明对于盈亏幅度较小的公司,削减R&D支出已经成为公司盈余管理的重要手段,我国机构投资者整体及证券投资基金持股与公司盈余管理行为显著负相关。另外验证了机构投资者持股比例较高时对国有控股公司及非国有控股公司的盈余管理行为都能发挥有效的抑制作用,但持股比例较低时对国有控股公司盈余管理行为的抑制作用显著小于非国有控股公司。     

FDI, transfer pricing and the measurement of R&D intensity

An important determinant of a region's attractiveness to foreign investors is its rate of corporation tax. Besides stimulating real economic activity, low corporation tax rates also induce multinational corporations to shift profits into the jurisdiction, frequently through the manipulation of transfer prices. This practice can lead to a substantial distortion of output figures. Since national or sectoral R&D intensities are usually measured relative to output, transfer pricing also therefore distorts these measurements. The present paper proposes a simple alternative measure of R&D intensity. Implementation on Irish data shows that the two approaches yield substantially different results.     

A case analysis of semantic technologies for R&D intermediation information management

It is evident that companies and research centres can find a myriad of instruments to fund their R&D (Research & Development) activities. Due to the dynamics of the information management in these circumstances there is a need for intermediary businesses intervention. Consequently, intermediary companies are thus involved in a complex process that needs to be managed and controlled. Within this scenario an Information Technology (IT) platform, named RDi-Advise, was developed by EgeoIT using semantic technologies to support R&D process decisions. This case analysis describes the development and implementation of the platform including the lessons learned during the activity period.     

R&D manpower and technological performance: The impact of demographic and task-related diversity

We assess the impact of R&D manpower diversity on firms’ technological performance. Relying on insights from two theoretical perspectives on team diversity (i.e. social categorization perspective and information decision-making perspective), we hypothesize that both demographic and task-related sources of diversity within firms’ R&D workforce influence technological performance. In addition, we expect that these two dimensions of diversity interact with each other. To test our hypotheses, we rely on survey data from 938 Singaporean firms, providing in-depth information on three sources of demographic diversity (i.e. gender, age, and nationality of R&D employees) and two sources of task-related diversity (i.e. educational and knowledge area background of R&D employees). Our findings point to significant interactions between different sources of R&D manpower diversity. In particular, we identify substitutive relationships between (a) educational and gender diversity, and (b) nationality and knowledge area diversity.