Heart Rate Holter Monitoring of 6- and 7-Year Old Children with Insulin Dependent Diabetes Mellitus Cardiovascular and Short Term Metabolic Response to Exercise: A Pilot Study

Abstract

This study examined whether gender and/or training were related to the exercise-induced changes in plasma concentrations of growth hormone (GH), prolactin (PRL), triiodothyronine (T₃), and thyroxine (T₄). Twenty subjects (male and female 10-km runners; untrained males and females) ran on a treadmill for 30 win at 80% of previously determined maximum heart rate. Blood samples were taken through an indwelling catheter from an antecubital vein at ?30, 0, +15, +30 min of the test and 30 min of recovery. Reded temperature rose significantly (p < .01) at +15 and +30 min with concomitant rise in GH concentration, but PRL, T₃, and T₄ were not affected by the exercise. We concluded that a 30-min run at 80% of maximum heart rate is associated with higher concentrations of GH but not of PRL, T₃, and T₄ Neither training state nor gender affected the aforementioned results.     

运动对中年糖耐量减低患者胰岛素抵抗及游离脂肪酸的影响

目的：探讨运动对中年糖耐量减低患者胰岛素抵抗、游离脂肪酸的影响。方法：将61名糖耐量减低患者随机分为健步走组20例、健步走＋抗阻力运动组20例、对照组21例，两运动组进行24周运动处方的锻炼，并与对照组对比。结果：两运动组24周运动干预前后胰岛素抵抗指数和血游离脂肪酸的差异具有显著性；与健步走组相比，健步走＋抗阻力运动组游离脂肪酸降低的幅度较明显。结论：对中年IGT患者进行运动干预可提高胰岛素敏感性，降低游离脂肪酸水平，且健步走＋抗阻力运动对游离脂肪酸降低的效果较健步走的大。     

胰岛素对缺血再灌注心肌的保护作用及其机制与运动干预的研究进展

目的:通过探讨胰岛素对缺血再灌注心肌的保护作用及其机制,分析运动干预的应用前景。方法:采用文献资料法、前瞻性分析与逻辑推理相结合的方法,总结胰岛素对缺血再灌注心肌的保护作用及其机制的研究进展以及在运动医学领域中所发挥的重要作用。结论:胰岛素可减轻缺血再灌注心肌细胞的炎症反应,增强心室肌细胞的收缩及钙的瞬变,减少心肌细胞凋亡,提高NO的含量,改善心肌超微结构的改变,从而抑制缺血再灌注过程中脂质过氧化物的升高,清除氧自由基,同时增加Akt的表达及活化,促进再灌注后心肌细胞功能的恢复,在此过程中激活PI3k途径,发挥对缺血再灌注心肌的保护作用。运动干预则与其发挥协同作用,增强对心肌的保护作用,有效地缓解缺血再灌注后心肌的损伤。