论中国烟草行业知识产权发展的现状与对策

长期以来,虽然我国烟草行业的知识产权在数量和质量上都取得了长足进步,但与国外烟草业相比,还存在着知识产权意识薄弱、自主知识产权水平不高、缺乏自身的国际竞争力等相关问题,直接制约着行业的发展和中国烟草总体竞争实力的提高.为构建知识经济条件下的知识产权战略运行机制,需要统一思想,树立高度重视知识产权建设的战略理念;立足专卖体制,建立知识产权建设的行业指导体系;放眼全球,积极建立先进的知识产权运营和竞争模式.     

Association of Inflammatory Cytokines,Lipid Peroxidation End Products and Nitric Oxide with the Clinical Severity and Fetal Outcome in Preeclampsia in Indian Women

Preeclampsia is a multisystem disorder associated with maternal hypertension, placental abnormalities and adverse fetal outcomes. The various pathways involved in its etiology include endothelial dysfunction, inflammatory milieu, lipid peroxidation and immunological imbalance. The present study was conducted to evaluate the causative and predictive role of nitric oxide, lipid peroxidation end products (MDA) and inflammatory cytokines (IL-6, TNF-α) in clinical presentation, severity and fetal outcome in preeclampsia. The study population was divided into 3 groups- Non- pregnant females comprising the control population; G1 and G2 groups included normal pregnant and pregnant females with preeclampsia with 50 patients in each group. Nitric Oxide and MDA levels were found to be highest in the preeclamptic patients as compared to other two groups. ROC curve analysis shows the superiority of the inflammatory markers as determinants of severity of preeclampsia which suggests the emerging role of pro inflammatory markers in the various pathological changes in preeclampsia. TNF-α emerged as the best marker in multivariate analysis and thus, has the potential for being used as a marker for PIH. Our study illustrates the multifactorial etiology of preeclampsia involving oxidative stress, proinflammatory milieu and endothelial dysfunction.     

不同药剂处理对低温逆境下烟草种子发芽和幼苗生长的影响

研究了不同药剂处理对低温逆境下不同耐寒力烟草品种种子发芽和幼苗生长的影响。采用不同浓度的外源脯氨酸、水杨酸、氯化钙、甘油、二甲基亚砜、乙二醇、聚乙二醇、丙二醇、烯效唑、脱落酸对不同耐寒力烟草品种种子浸种处理后,测定了低温逆境下不同烟草品种发芽及幼苗生长和生理生化指标变化。结果表明,脯氨酸、水杨酸、氯化钙、二甲基亚砜和聚乙二醇5种药剂浸种能显著促进烟草种子发芽,提高了低温逆境下幼苗根长、苗高、幼苗干鲜重以及超氧化物歧化酶(SOD)、过氧化物酶(POD)、过氧化氢酶(CAT)和抗坏血酸过氧化物酶(APX)活性,其中10 g/L脯氨酸、120 mg/L水杨酸、15 mg/L氯化钙、30 ml/L二甲基亚砜和100 ml/L聚乙二醇综合效果较好,可以作为提高烟草种子及幼苗抗寒性的处理方法。