Nausea is associated with endotoxemia during a 161-km ultramarathon

This study explored possible contributing factors to gastrointestinal distress, including endotoxemia, hyperthermia, dehydration and nutrition, during a 161-km ultramarathon. Thirty runners participated in the study and 20 finished the race. At three checkpoints and the finish, runners were interviewed to assess the incidence and severity of 12 gastrointestinal symptoms and to determine dietary intake. Core temperature was measured at the same locations. Runners were weighed pre-race, at the three checkpoints and the finish to monitor hydration status. Blood markers for endotoxemia (sCD14) and inflammation (interleukin-6 and C-reactive protein) were measured pre- and post-race. Gastrointestinal symptoms were experienced by most runners (80%), with nausea being the most common complaint (60%). Runners with nausea experienced significantly greater (P = 0.02) endotoxemia than those without nausea (sCD14 mean increase 0.7 versus 0.5 µg · mL^?1). There was a significant positive correlation (r = 0.652, P = 0.005) between nausea severity and endotoxemia level. Inflammatory response, core temperature, hydration level and race diet were similar between runners with and without nausea. This study links endotoxemia to nausea in ultramarathon runners. Other possible contributing factors to nausea such as hyperthermia, dehydration and nutrition did not appear to play a role in the symptomatic runners in this study.     

Determinants of recovery from a 161-km ultramarathon

The primary study objective was to identify determinants of short-term recovery from a 161-km ultramarathon. Participants completed 400 m runs at maximum speed before the race and on days 3 and 5 post-race, provided a post-race blood sample for plasma creatine kinase (CK) concentration, and provided lower body muscle pain and soreness ratings (soreness, 10-point scale) and overall muscular fatigue scores (fatigue, 100-point scale) pre-race and for 7 days post-race. Among 72 race finishers, soreness and fatigue had statistically returned to pre-race levels by 5 days post-race; and 400 m times at days 3 and 5 remained 26% (P = 0.001) and 12% (P = 0.01) slower compared with pre-race, respectively. CK best modelled soreness, fatigue and per cent change in post-race 400 m time. Runners with the highest CKs had 1.5 points higher (P < 0.001) soreness and 11.2 points higher (P = 0.006) fatigue than runners with the lowest CKs. For the model of 400 m time, a significant interaction of time with CK (P < 0.001) indicates that higher CKs were linked with a slower rate of return to pre-race 400 m time. Since post-race CK was the main modifiable determinant of recovery following the ultramarathon, appropriate training appears to be the optimal approach to enhance ultramarathon recovery.     

A faster running speed is associated with a greater body weight loss in 100-km ultra-marathoners

Abstract

In 219 recreational male runners, we investigated changes in body mass, total body water, haematocrit, plasma sodium concentration ([Na⁺]), and urine specific gravity as well as fluid intake during a 100-km ultra-marathon. The athletes lost 1.9 kg (s = 1.4) of body mass, equal to 2.5% (s = 1.8) of body mass (P < 0.001), 0.7 kg (s = 1.0) of predicted skeletal muscle mass (P < 0.001), 0.2 kg (s = 1.3) of predicted fat mass (P < 0.05), and 0.9 L (s = 1.6) of predicted total body water (P < 0.001). Haematocrit decreased (P < 0.001), urine specific gravity (P < 0.001), plasma volume (P < 0.05), and plasma [Na⁺] (P < 0.05) all increased. Change in body mass was related to running speed (r = ?0.16, P < 0.05), change in plasma volume was associated with change in plasma [Na⁺] (r = ?0.28, P < 0.0001), and change in body mass was related to both change in plasma [Na⁺] (r = ?0.36) and change in plasma volume (r = 0.31) (P < 0.0001). The athletes consumed 0.65 L (s = 0.27) fluid per hour. Fluid intake was related to both running speed (r = 0.42, P < 0.0001) and change in body mass (r = 0.23, P = 0.0006), but not post-race plasma [Na⁺] or change in plasma [Na⁺] (P > 0.05). In conclusion, faster runners lost more body mass, runners lost more body mass when they drank less fluid, and faster runners drank more fluid than slower runners.     

Russians are the fastest and the youngest in the “Comrades Marathon”

The present retrospective study intended to determine age, performance, the role of nationality and participation trends across calendar years in runners competing in “Comrades Marathon”, the ultra-marathon with the longest tradition and the highest number of finishers worldwide. We analysed 235,467 finishers (40,211 women and 195,256 men) competing between 1994 and 2017. In women and men, Russians were the fastest (12.55 ± 2.03 km/h and 12.24 ± 2.93 km/h, respectively) and Indians the slowest (7.87 ± 0.64 km/h and 7.91 ± 0.60 km/h) (p < 0.001, η2 = 0.053 and η2 = 0.010, small effect size, ES). Also, Russians were the youngest (33.9 ± 4.6 and 36.3 ± 5.9 years, respectively) and Japanese the oldest (49.3 ± 9.6 and 51.4 ± 12.3 years, respectively) (p < 0.001, η2 = 0.011, small ES). Performance improved (r = 0.90 in women and r = 0.92 in men), age of finishers (r = 0.91 in women and r = 0.97 in men), participation (r = 0.92 in women and r = 0.87 in men) and sex difference in age increased (r = 0.71), whereas men-to-women ratio (r = ?0.91) and sex difference in performance (r = ?0.68) decreased across calendar years (p < 0.001). In summary, runners from Russia were the fastest and the youngest in both sexes. The knowledge of the relationship of nationality with performance, age and participation trends of finishers, and changes across calendar years are of practical importance for ultra-runners and coaches working with them.     

Comparison of three-dimensional lower extremity running kinematics of young adult and elderly runners

Abstract

The objective of this study was to compare the three-dimensional lower extremity running kinematics of young adult runners and elderly runners. Seventeen elderly adults (age 67–73 years) and 17 young adults (age 26–36 years) ran at 3.1 m · s^?1 on a treadmill while the movements of the lower extremity during the stance phase were recorded at 120 Hz using three-dimensional video. The three-dimensional kinematics of the lower limb segments and of the ankle and knee joints were determined, and selected variables were calculated to describe the movement. Our results suggest that elderly runners have a different movement pattern of the lower extremity from that of young adults during the stance phase of running. Compared with the young adults, the elderly runners had a substantial decrease in stride length (1.97 vs. 2.23 m; P = 0.01), an increase in stride frequency (1.58 vs. 1.37 Hz; P = 0.002), less knee flexion/extension range of motion (26 vs. 33°; P = 0.002), less tibial internal/external rotation range of motion (9 vs. 12°; P < 0.001), larger external rotation angle of the foot segment (toe-out angle) at the heel strike (?5.8 vs. ?1.0°; P = 0.009), and greater asynchronies between the ankle and knee movements during running. These results may help to explain why elderly individuals could be more susceptible to running-related injuries.     

Lacrosse Legends of the First Americans

Abstract

The purpose of this study was to examine the distribution of pace self-selected by cyclists of varying ability, biological age and sex performing in a mountain bike World Championship event. Data were collected on cyclists performing in the Elite Male (ELITE_male; n = 75), Elite Female (ELITE_female; n = 50), Under 23 Male (U23_male; n = 62), Under 23 Female (U23_female; n = 34), Junior Male (JNR_male; n = 71) and Junior Female (JNR_female; n = 30) categories of the 2009 UCI Cross-Country Mountain Bike World Championships. Split times were recorded for the top, middle and bottom 20% of all finishers of each category. Timing splits were positioned to separate the course into technical and non-technical, uphill, downhill and rolling/flat sections. Compared with bottom performers, top performers in all male categories (ELITE_male, U23_male, JNR_male) maintained a more even pace over the event as evidenced by a significantly lower standard deviation and range in average lap speed. Top performers, males, and ELITE_male athletes spent a lower percentage of overall race time on technical uphill sections of the course, compared with middle and bottom placed finishers, females, and JNR_male athletes, respectively. Better male performers adopt a more even distribution of pace throughout cross-country mountain events. Performance of lower placed finishers, females and JNR_male athletes may be improved by enhancing technical uphill cycling ability.     

Foot strike patterns of recreational and sub-elite runners in a long-distance road race

Abstract

Although the biomechanical properties of the various types of running foot strike (rearfoot, midfoot, and forefoot) have been studied extensively in the laboratory, only a few studies have attempted to quantify the frequency of running foot strike variants among runners in competitive road races. We classified the left and right foot strike patterns of 936 distance runners, most of whom would be considered of recreational or sub-elite ability, at the 10 km point of a half-marathon/marathon road race. We classified 88.9% of runners at the 10 km point as rearfoot strikers, 3.4% as midfoot strikers, 1.8% as forefoot strikers, and 5.9% of runners exhibited discrete foot strike asymmetry. Rearfoot striking was more common among our sample of mostly recreational distance runners than has been previously reported for samples of faster runners. We also compared foot strike patterns of 286 individual marathon runners between the 10 km and 32 km race locations and observed increased frequency of rearfoot striking at 32 km. A large percentage of runners switched from midfoot and forefoot foot strikes at 10 km to rearfoot strikes at 32 km. The frequency of discrete foot strike asymmetry declined from the 10 km to the 32 km location. Among marathon runners, we found no significant relationship between foot strike patterns and race times.     

Circles on pommel horse with a suspended aid: Spatio-temporal characteristics

Abstract

We investigated the associations of anthropometry, training, and pre-race experience with race time in 93 recreational male ultra-marathoners (mean age 44.6 years, s = 10.0; body mass 74.0 kg, s = 9.0; height 1.77 m, s = 0.06; body mass index 23.4 kg · m^?2, s = 2.0) in a 100-km ultra-marathon using bivariate and multivariate analysis. In the bivariate analysis, body mass index (r = 0.24), the sum of eight skinfolds (r = 0.55), percent body fat (r = 0.57), weekly running hours (r = ?0.29), weekly running kilometres (r = ?0.49), running speed during training (r = ?0.50), and personal best time in a marathon (r = 0.72) were associated with race time. Results of the multiple regression analysis revealed an independent and negative association of weekly running kilometres and average speed in training with race time, as well as a significant positive association between the sum of eight skinfold thicknesses and race time. There was a significant positive association between 100-km race time and personal best time in a marathon. We conclude that both training and anthropometry were independently associated with race performance. These characteristics remained relevant even when controlling for personal best time in a marathon.     

Perceived life stress and anxiety correlate with chronic gastrointestinal symptoms in runners

Numerous causes of exercise-related gastrointestinal (GI) distress exist but scarce research has evaluated potential psychological causes. Runners (74 men, 76 women) prospectively recorded running duration, intensity (Rating of Perceived Exertion [RPE]), and GI symptoms for 30 days. Six GI symptoms were rated on a 0–10 scale. The percentage of runs over 30 days that participants reported at least one upper, lower, or any GI symptom ≥3 was calculated. After 30 days, participants completed a questionnaire on GI distress triggers (demographics, anthropometrics, experience, analgesic use, antibiotic use, probiotic consumption, fluid/food intake, stress, anxiety). Stress and anxiety were measured via the Perceived Stress Scale (PSS) and Beck Anxiety Inventory (BAI). The median percentage of runs that participants experienced at least one GI symptom ≥3 was 45.6% (interquartile range [IQR], 16.6–67.3%). Age and running experience negatively correlated with GI distress occurrence (rho = ?0.17 to ?0.34; p < 0.05). Run RPE, probiotic food consumption, PSS scores, and BAI scores positively correlated with GI distress occurrence (rho = 0.18 to 0.36; p < 0.05). Associations between GI distress, stress and anxiety remained significant after adjustment for covariates, except for lower GI symptoms. This study suggests that stress and anxiety contribute to running-related GI distress.     

America's Cup yacht racing: Race analysis and physical characteristics of the athletes

Abstract

The America's Cup is the oldest competing trophy in sport, yet little is known of the nature and intensity of racing or the physical characteristics of the athletes. In this study, aspects of the physical demands of America's Cup yacht racing were analysed, including the intensity of exercise and activity pattern of “grinding”. Anthropometric data were collected from 92 professional male America's Cup sailors, and fitness data from a top-4 and a lower-7 ranking team during the 32nd America's Cup. Over the 135 races, mean race duration was 82 min (s = 9), with 20 tacks (s = 10) and 8 gybes (s = 3) per race. Grinding bouts were 5.5 s (s = 5.4; range: 2.2–66.3) long, with 143 exercise bouts per race and an exercise-to-rest ratio of 1:6. Mean and peak heart rate was 64% and 92% of maximum for all positions, with bowmen highest (71% and 96%). Grinders were taller, heavier, and stronger than all other positions. Body fat was similar between positions (13%, s = 4). The higher-standard team was stronger and had greater strength endurance, which probably contributed to their quicker manoeuvres. Intensity of exercise was dependent on the similarity of competing boats and the role of the athlete. The short duration and intermittent nature of grinding is indicative of predominantly anaerobic energy provision.     

Underwater and surface strategies of 200 m world level swimmers

Pacing strategies of elite swimmers have been consistently characterised from the average lap velocities. In the present study, we examined the racing strategies of 200 m world class-level swimmers with regard to their underwater and surface lap components. The finals and semi-finals of the 200 m races at the 2013 World Swimming Championships (Barcelona, Spain) were analysed by an innovative image-processing system (InThePool® 2.0). Free swimming velocities of elite swimmers typically decreased throughout the 200 m race laps (?0.12 m · s^–1, 95% CI ?0.11 to ?0.14 m · s^–1, P = 0.001, η² = 0.81), whereas underwater velocities, which were faster than free swimming, were not meaningfully affected by the race progress (0.02 m · s^–1, ?0.01 to 0.04 m · s^–1, P = 0.01, η² = 0.04). When swimming underwater, elite swimmers typically travelled less distance (?0.66 m, ?0.83 to ?0.49 m, P = 0.001, η² = 0.34) from the first to the third turn of the race, although underwater distances were maintained on the backstroke and butterfly races. These strategies allowed swimmers to maintain their average velocity in the last lap despite a decrease in the free swimming velocity. Elite coaches and swimmers are advised to model their racing strategies by considering both underwater and surface race components.     

Foot strike patterns and ground contact times during high-calibre middle-distance races

Abstract

The aims of this study were to examine ground contact characteristics, their relationship with race performance, and the time course of any changes in ground contact time during competitive 800 m and 1500 m races. Twenty-two seeded, single-sex middle-distance races totalling 181 runners were filmed at a competitive athletics meeting. Races were filmed at 100 Hz. Ground contact time was recorded one step for each athlete, on each lap of their race. Forefoot and midfoot strikers had significantly shorter ground contact times than heel strikers. Forefoot and midfoot strikers had significantly faster average race speed than heel strikers. There were strong large correlations between ground contact time and average race speed for the women's events and men’s 1500 m (r = ?0.521 to ?0.623; P < 0.05), whereas the men's 800 m displayed only a moderate relationship (r = ?0.361; P = 0.002). For each event, ground contact time for the first lap was significantly shorter than for the last lap, which might reflect runners becoming fatigued.     

Repeatability of scores on a novel test of endurance running performance

Abstract

The aim of the present study was to determine the repeatability of a running endurance test using an automated treadmill system that requires no manual input to control running speed. On three separate occasions, 7 days apart, 10 experienced male endurance-trained runners (mean age 32 years, s = 10; [Vdot]O_2peak 61 ml · kg^?1 · min^?1, s = 7) completed a treadmill time trial, in which they were instructed to run as far as possible in 60 min. The treadmill was instrumented with an ultrasonic feedback-controlled radar modulator that spontaneously regulated treadmill belt speed corresponding to the changing running speed of each runner. Estimated running intensity was 70%[Vdot]O_2peak (s = 11) and the distance covered 13.5 km (s = 2), with no difference in mean performances between trials. The coefficient of variation, estimated using analysis of variance, with participant and trial as main effects, was 1.4%. In summary, the use of an automated treadmill system improved the repeatability of a 60-min treadmill time trial compared with time trials in which speed is controlled manually. The present protocol is a reliable method of assessing endurance performance in endurance-trained runners.     

Bone health in elite Kenyan runners

Impact loading in athletes participating in various sports has been positively associated with increased bone mineral density (BMD), but this has not been investigated in elite Kenyan runners. Body composition and site-specific BMD measures quantified with dual x-ray absorptiometry were measured in 15 elite male Kenyan runners and 23 apparently healthy South African males of different ethnicities. Training load and biomechanical variables associated with impact loading, such as joint stiffness, were determined in the elite Kenyan runners. Greater proximal femur (PF) BMD (g · cm^?2) was higher (P = 0.001, ES = 1.24) in the elite Kenyan runners compared with the controls. Six of the 15 (40%) Kenyan runners exhibited lumbar spine (LS) Z-Scores below ?2.0 SD, whereas this was not found in the apparently healthy controls. PFBMD was associated with training load (r = 0.560, P = 0.003) and ankle (r = 0.710, P = 0.004) and knee (r = 0.546, P = 0.043) joint stiffness. Elite Kenyan runners exhibit greater PFBMD than healthy controls, which is associated with higher training load and higher joint stiffness. Our results reaffirm the benefits of impact loading on BMD at a weight-bearing site, while a high prevalence of low LSBMD in the elite Kenyan runners is hypothesised to be the result of a mismatch between energy intake and high training load. Future research investigating energy availability in Kenyan runners and the possible association with musculoskeletal injury should be investigated.     

Influence of ingesting a carbohydrate-electrolyte solution before and during a 1-hour run in fed endurance-trained runners

Abstract

The aim of this study was to determine whether the ingestion of a carbohydrate-electrolyte solution would improve 1-h running performance in runners who had consumed a meal 3 h before exercise. Ten endurance-trained male runners completed two trials that required them to run as far as possible in 1 h on an automated treadmill that allowed changes in running speed without manual input. Following the consumption of the pre-exercise meal, which provided 2.5 g carbohydrate per kilogram body mass (BM), runners ingested either a 6.4% carbohydrate-electrolyte solution or placebo solution (i.e. 8 ml · kg BM^?1) 30 min before and 2 ml · kg BM^?1 at 15-min intervals throughout the 1-h run. There were no differences in total distance covered (placebo: 13,680 m, s = 1525; carbohydrate: 13,589 m, s = 1635) (P > 0.05). Blood glucose and lactate concentration, respiratory exchange ratio, and carbohydrate oxidation during exercise were not different between trials (P > 0.05). There were also no differences in ratings of perceived exertion, felt arousal or pleasure–displeasure between trials (P > 0.05). In conclusion, the ingestion of a 6.4% carbohydrate-electrolyte solution did not improve 1-h running performance when a high carbohydrate meal was consumed 3 h before exercise.     

Combined effects of sleep deprivation and strenuous exercise on cognitive performances during The North Face® Ultra Trail du Mont Blanc® (UTMB®)

This study investigated the effects of combined sleep deprivation and strenuous exercise on cognitive and neurobehavioral performance among long-distance runners completing one of the most difficult ultramarathons in the world. Seventeen runners participated. Each had a wrist-worn actigraph throughout the race to record their sleep time. In addition, each individual’s performance in 10-min response-time tests before and after the race was recorded and a questionnaire enabled participants to report any difficulties they experienced during the competition. During race completion times of 27 to 44 h, combined acute lack of sleep (12 ± 17 min of rest during the race) and strenuous exercise (168.0 km) had marked adverse effects on cognitive performances ranging from mere lengthening of response time to serious symptoms such as visual hallucinations. This study suggests that regardless of rest duration and time in race, cognitive performances of ultramarathoners are adversely affected.     

The age-related performance decline in marathon cross-country skiing – the Engadin Ski Marathon

Demographic and performance data from 197,825 athletes competing in “Engadin Ski Marathon” between 1998 and 2016 were analysed. When all finishers per age group were considered, there was no gender difference in time (2:59:00 in women versus 2:59:09 h:min:s in men; P = 0.914, η² < 0.001) and the main effect of age group on time was trivial (P < 0.001, η² = 0.007). When the top 10 finishers per age group were considered, men were faster than women (1:27:32 versus 1:34:19 h:min:s, respectively; P < 0.001, η² = 0.373), there was a large effect of age group on time (P < 0.001, η² = 0.590) and the gender difference was larger in the older than in the younger age groups (P < 0.001, η² = 0.534). The age of peak performance for all finishers by 1-year interval age group was 40.3 and 39.6 years in all women and men, respectively. The top 10 finishers by 1-year interval age group achieved their peak performance in the age of 38.4 and 42.2 years in women and men, respectively. The age of peak performance was older and the age-related performance decline occurred earlier in marathon cross-country skiing, compared to road-based marathon running.     

Index of mechanical efficiency in competitive and recreational long distance runners

The purpose of this investigation was to compare external work and net energy expenditure during a bout of repetitive stretch-shortening cycles between competitive and recreational long-distance runners. Participants were divided into either competitive or recreational runners based on their maximal oxygen consumption and self-reported 1600 m times. The stretch-shortening cycle involved a repetitive hopping protocol on a force plate while measuring oxygen consumption and lactate accumulation for a total of 10 min. External work and net energy expenditure were calculated for 3 min after steady state was achieved and the ratio between these variables was utilised as an index of mechanical efficiency. Lower extremity stiffness was calculated during this interval as well. Net energy expenditure was significantly lower in competitive runners (152.6 ± 33.3 kJ) in comparison to recreational runners (200.6 ± 41.4 kJ) (P = 0.02) given similar amounts of external work performed in both groups (competitive runners = 65.6 ± 20.1 kJ, recreational runners = 68.8 ± 12.1 kJ) (P = 0.67). Index of mechanical efficiency was significantly different between competitive runners (43.2 ± 9.0%) and recreational runners (34.8 ± 5.3%) (P = 0.03). No significant differences were found in lower extremity stiffness (P = 0.64). Competitive distance runners can perform similar levels of external work with lower net energy expenditure and thus a higher index of mechanical efficiency during repetitive stretch-shortening cycles in comparison to recreational runners with similar values of lower extremity stiffness. This ability could possibly be due differences in muscle–tendon length changes, muscle pre-activation, cross-bridge potentiation and short-latency reflex responses as a result of training which should be considered for future investigation.     

The effect of breast support and breast pain on upper-extremity kinematics during running: implications for females with large breasts

The relationship between inappropriate breast support and upper-extremity kinematics for female runners is unclear. The purpose of this study was to investigate the effect of breast support and breast pain on upper-extremity kinematics during running. Eleven female recreational runners with larger breasts (UK D and E cup) completed a 7 min 20 s treadmill run (2.58 m · s^?1) in a high and low breast support condition. Multi-planar breast and upper-extremity kinematic data were captured in each breast support condition by eight infrared cameras for 30 s towards the end of the run. Breast pain was rated at the end of each treadmill run using a numeric analogue scale. The high support bra reduced breast kinematics and decreased breast pain (P < 0.05). Upper-extremity kinematics did not differ between breast support conditions (P > 0.05), although some moderate positive correlations were found between thorax range of motion and breast kinematics (r = 0.54 to 0.73). Thorax and arm kinematics do not appear to be influenced by breast support level in female runners with large breasts. A high support bra that offers good multi-planar breast support is recommended for female runners with larger breasts to reduce breast pain.     

The effect of caffeine ingestion on 8 km run performance in a field setting

Abstract

The aim of this study was to assess the effect of caffeine ingestion on 8 km run performance using an ecologically valid test protocol. A randomized double-blind crossover study was conducted involving eight male distance runners. The participants ran an 8 km race 1 h after ingesting a placebo capsule, a caffeine capsule (3 mg · kg^?1 body mass) or no supplement. Heart rate was recorded at 5 s intervals throughout the race. Blood lactate concentration and ratings of perceived exertion were recorded after exercise. A repeated-measures analysis of variance (ANOVA) identified a significant treatment effect for 8 km performance time (P < 0.05); caffeine resulted in a mean improvement of 23.8 s (95% confidence interval [CI] = 13.1 to 34.5 s) in 8 km performance time (1.2% improvement, 95% CI = 0.7 to 1.8%). In addition, a two-way (time × condition) repeated-measures ANOVA identified a significantly higher blood lactate concentration 3 min after exercise during the caffeine trial (P < 0.05). We conclude that ingestion of 3 mg · kg^?1 body mass of caffeine can improve absolute 8 km run performance in an ecologically valid race setting.