香砂六君子汤联合多潘立酮治疗功能性消化不良的meta分析

目的:评价香砂六君子汤联合多潘立酮治疗FD临床疗效.方法:通过检索中文数据库,收集香砂六君子汤联合多潘立酮治疗FD随机对照研究.按纳入排除标准筛选文献,采用Jadad质量评分表对文献进行评价,提取有效数据,用RevMan5.0软件包进行统计分析.结果:临床治疗有效率:异质性检验P＞0.1,表明研究数据具有同质性,故采用固定效应模式.合并效应量RR=1.18,95％CI(1.12,1.24);合并效应量的检验Z=5,P＜0.00001.痊愈率:异质性检验P＞0.1,表明研究数据具有同质性,故采用固定效应模式.合并效应量RR=1.52,95％CI(1.21,1.90);合并效应量的检验Z=3,P＜0.00001.表明香砂六君子汤联合多潘立酮治疗FD总效率及痊愈率相对单独使用西医有明显优势.漏斗图显示不对称,提示纳入评价的文献存在发表性偏倚.结论:香砂六君子汤联合多潘立酮治疗FD疗效明显优于西药治疗,但是由于本次纳入的文献质量较低,仍须严格科学设计临床研究方案,进行多中心、大样本的随机双盲对照研究,以提供更有力的证据.     

图的Perron向量分量的界

Perron向量的研究可以应用到图的谱半径的估计,并可以通过移接变形对图类进行谱半径排序.证明对完全图和一个孤立点间进行加边时该孤立点所对应的Perron向量分量是变大的.以及猜想Perron向量的最小分量由孤立点在只与完全图连一条边时达到.     

基于互惠性偏好的异质性管理团队隐性知识转移研究

管理团队内部异质性是决定隐性知识转移效率的关键因素,但已有研究对异质性如何影响团队知识转移的作用机理还缺乏系统的理论分析和实证研究.本文在实地调查基础上,引入互惠性偏好作为情境因素,对团队异质性是否通过互惠性偏好对团队隐性知识转移产生影响进行实证研究.研究结果发现:知识结构异质性对隐性知识转移产生不利影响,职业背景异质性对隐性知识转移有一定的积极影响,互惠性偏好在管理团队异质性和隐性知识转移中存在调节效应.     

国内大学生网络成瘾影响因素的元分析

本文运用元分析技术对国内近7年间20篇相关实证研究文献进行分析.结果显 示,(1)理工科男生是网络成瘾的易发群体,但人口因素对网络成瘾影响效应量非常小 (| r |＜0.184);(2)外在因素中的生活事件和社会支持,内在因素中的应对方式、口EPQ人格 特质、心理健康、抑郁、孤独和自尊均会影响大学生网络成瘾,但影响效应量均为小效应量 (| r | ＜0.278);(3)大多数有关网络成瘾影响因素的已有研究结果存有显著的异质性 (P＜0.05).在一定条件下,每位大学生均可能网络成瘾,网络成瘾现象是人类生物本性使 然;大学生网络成瘾并非由某一因素单独作用所致,而是由多种因素共同作用的结果;导致 该领域以往研究结果异质性的原因是研究工具、测试方式和研究对象相异.     

物理知识结构图在高中物理学习中的用途

核心素养导向的物理教学设计要采用多种教学策略,教给学生研究问题的方法.物理知识结构图也是一种研究问题的方法.通过实例说明物理知识结构图在高中物理学习中的用途.应用物理知识结构图可以帮助学生构建学科知识体系框架、整合解题方法、具化思维过程.在教学中引入物理知识结构图,提供给学生研究问题方法更多的选择.     

用电压表比较液体密度大小

用易观察的量显示不易观察的量,是制作测量仪器的一个重要技术思路.2007年中考试题中,将这一思路恰当地与所学实验和仪器结合了起来,在教材已有实验的基础上,进行改进和创新,用来考查学生灵活运用知识的能力和创新能力,我们以2007年青岛市中考第9题为例,讨论这类试题的解题方法.例题(2007年青岛市中考第9题)晓丽在研究磁场对电流作用的实验中,将直导线换成一块厚度为 d、宽度为 b 的导体板.如图1所示,将电压表连在导体板的两侧,发现电压表指针发生偏转.进一步做了如下实验:     

碳纳米管中储氢特征的分子动力学研究

前期采用巨正则分子动力学方法对碳纳米管储氢进行模拟计算,得到了较理想的重量储氢量。但对碳纳米管内的储氢位形没有直观的认识。本文通过模拟计算,得到了不同管径的碳纳米管在不同温度、压强下的储氢位形图,从而直观的展示了碳纳米管的储氢特征。为研究碳纳米管储氢机理并提高重量储氢量提供参考。     

现象图析学:一种中观层面的教育学研究方法论

现象图析学是瑞典哥德堡大学教育学系的研究团队发明并使用的一种教育研究方式,属于教育研究领域一种中观层面的方法论,拥有独特的本体论、认识论、方法论假设.现象图析学的本体论假设,即知识并非绝然的客观真理,而是个体观念与外部现实世界交互式作用的结果.认识论假设,即描述是获得个体对于具体事物观念的基本认识方式.方法论假设,即强调数据收集过程中的探索性特征以及数据分析过程中的情境性特征.现象图析学旨在对个体对于周遭世界体验的现象进行描述,涉及的主要内容包括一阶观点和二阶观点、差异、质的差异的(理解)方式、描述的分类等.近年来,教育研究领域使用现象图析学完成的经验性研究数量与日俱增,但其尚未引起我国大陆学者的高度重视.     

南疆地区高校教师队伍建设的异质性分析

教师队伍建设的本质是具体的,高校教师队伍建设因地域性、高校类型、办学层次、定位的不同而表现出一定的异质性.高校教师队伍建设的方法和策略如果缺乏针对性,就会在实践中出现无所适从的局面.因此,无论是考察教师队伍建设现状,还是探讨其原因、对策等,都必须根植于高校教师队伍的异质性研究.探讨民族异质性、地区异质性和高校自身管理的异质性对高校教师队伍建设的影响,这对南疆地区而言,尤其具有说服力.     

测定带电粒子荷质比的常见方法

带电粒子的荷质比是带电粒子的一个重要特征量 ,必须通过实验进行测定 .测定带电粒子的荷质比的方法有很多 ,笔者归纳出 4种常见方法 .方法 1　利用速度选择器测量例 1　图 1所示为一种可用于测量电子电荷 e与质量 m比值 e/ m的阴极射线管 ,管内处于真空状态 .图中 L是灯丝 ,当     

The empirical review of meta-analysis published in Korea

Meta-analysis is a statistical method that is increasingly utilized to combine and compare the results of previous primary studies. However, because of the lack of comprehensive guidelines for how to use meta-analysis, many meta-analysis studies have failed to consider important aspects, such as statistical programs, power analysis, publication bias, model selection, test of heterogeneity, and identification of heterogeneity. Therefore, the current study reviewed 84 meta-analysis studies conducted in Korea to examine proper application of the six categories named above. With regard to the issue of effect sizes, it was found that most of the meta-analysis studies obtained more than ten effect sizes, which seem to be an adequate number for representing an issue. However, many studies failed to consider the other issues: power analysis, publication bias, model selection, test of heterogeneity, and identification of heterogeneity.     

A Meta-Analysis on Gender Differences in Mental Rotation Ability Measured by the Purdue Spatial Visualization Tests: Visualization of Rotations (PSVT:R)

This meta-analysis was conducted to estimate the magnitude of gender difference in three-dimensional (3-D) mental rotation ability and to investigate how factors related to test administration conditions play a role in varying gender difference effect sizes and threatening validity. Individuals’ 3-D mental rotation ability was measured by the Purdue Spatial Visualization Tests: Visualization of Rotations (PSVT:R). We integrated 70 effect sizes of gender differences in mental rotation ability measured by the PSVT:R which were obtained from 40 primary studies. The results indicated that male participants outperformed females on the test (Hedges’ g?=?0.57). The I ² statistic indicated 41.7 % of variation in effect sizes reflects real heterogeneity. The moderator analysis indicated that male superiority on spatial ability tasks measured by the PSVT:R is related to the implementation of time limits. The gender difference became larger when stringent time limits (equal or less than 30 s per item) were implemented.     

Evaluation of a New Mean Scaled and Moment Adjusted Test Statistic for SEM

Recently a new mean scaled and skewness adjusted test statistic was developed for evaluating structural equation models in small samples and with potentially nonnormal data, but this statistic has received only limited evaluation. The performance of this statistic is compared to normal theory maximum likelihood and 2 well-known robust test statistics. A modification to the Satorra–Bentler scaled statistic is developed for the condition that sample size is smaller than degrees of freedom. The behavior of the 4 test statistics is evaluated with a Monte Carlo confirmatory factor analysis study that varies 7 sample sizes and 3 distributional conditions obtained using Headrick's fifth-order transformation to nonnormality. The new statistic performs badly in most conditions except under the normal distribution. The goodness-of-fit χ² test based on maximum-likelihood estimation performed well under normal distributions as well as under a condition of asymptotic robustness. The Satorra–Bentler scaled test statistic performed best overall, whereas the mean scaled and variance adjusted test statistic outperformed the others at small and moderate sample sizes under certain distributional conditions.     

单因素方差分析中有关统计量的计算

通过列表计算或利用计算器完成单因素试验的方差分析中有关统计量的计算比较麻烦,针对这个问题,根据单因素方差分析的理论,结合列表计算的方法,用Basic语言编写了计算组间平均平方和,误差平均平方和,完成单因素方差分析的程序.利用该程序,计算的工作可以由计算机完成.     

Maximum Likelihood Estimation of Structural Equation Models for Continuous Data: Standard Errors and Goodness of Fit

Classical accounts of maximum likelihood (ML) estimation of structural equation models for continuous outcomes involve normality assumptions: standard errors (SEs) are obtained using the expected information matrix and the goodness of fit of the model is tested using the likelihood ratio (LR) statistic. Satorra and Bentler (1994) introduced SEs and mean adjustments or mean and variance adjustments to the LR statistic (involving also the expected information matrix) that are robust to nonnormality. However, in recent years, SEs obtained using the observed information matrix and alternative test statistics have become available. We investigate what choice of SE and test statistic yields better results using an extensive simulation study. We found that robust SEs computed using the expected information matrix coupled with a mean- and variance-adjusted LR test statistic (i.e., MLMV) is the optimal choice, even with normally distributed data, as it yielded the best combination of accurate SEs and Type I errors.     

XRCC1 Arg399Gln and clinical outcome of platinum-based treatment for advanced non-small cell lung cancer: a meta-analysis in 17 studies

Objective: XRCC1 polymorphism is a research hotpot in individual treatment for non-small cell lung cancer (NSCLC). To obtain the association between XRCC1 polymorphism and clinical outcome of platinum-based treatment for NSCLC, a meta-analysis was conducted. Methods: Databases including PubMed, Embase, Cochrane, and Chinese National Knowledge Infrastructure (CNKI) were searched for publications that met the inclusion criteria. A fixed effect model was used to estimate pooled odds ratio (OR) and hazard ratio (HR) with 95% confidence interval (CI) for the association between XRCC1 Arg399Gln and response or survival of platinum-based treatment for advanced NSCLC. A chi-squared-based Q-test was used to test the heterogeneity hypothesis. Egger’s test was used to check publication bias. Results: Seventeen published case-control studies that focus on the association between XRCC1 Arg399Gln and response or survival of platinum-based treatment for advanced NSCLC in 2 256 subjects were included in this meta-analysis, of whom 522 were AA genotypes (23.2% frequency), 916 AG genotypes (40.6% frequency), and 818 GG genotypes (36.2% frequency). The overall response rate (ORR) was 45.2% (110/243) for AA genotype patients, 29.9% for AG genotype (73/244), and 30.7% for GG genotype (124/403). The heterogeneity test did not show any heterogeneity and the Egger’s test did not reveal an obvious publication bias among the included studies. The meta-analysis indicated that AA genotype patients presented higher response rates toward platinum drug treatment compared with G model (GG+GA) patients (GG vs. AA model: OR=0.489, 95% CI 0.266–0.900, P=0.021; AG vs. AA model: OR=0.608, 95% CI 0.392–0.941, P=0.026; GA+AA vs. GG model: OR=1.259, 95% CI 0.931–1.701, P=0.135; GG+GA vs. AA model: OR=0.455, 95% CI 0.313–0.663, P=0.0001). However, no evidence validates XRCC1 associates with the survival following platinum drug therapy. Conclusions: Our meta-analysis suggested that XRCC1 Arg399Gln is related with the sensitivity of NSCLC patients to platinum-based treatment. AA genotype patients present more desirable curative effectiveness compared with other patients.     

初探图书馆统计分析工作

阐述了统计分析的概念和图书馆开展统计分析的必要性，并提出了图书馆加强统计分析工作的措施．     

成绩分析指标及其系统应用

考试是对学生学习状况进行检验的有效手段。对考试成绩进行统计分析,可以帮助教师找出教学及命题中的不足,更好地改进教学。总结常用的成绩分析指标,利用这些指标构建一个在线成绩分析系统,并给出系统应用的一个具体实例。实验结果表明,这些指标能够较好地对考试效果进行评价。     

考试质量在线测评系统的设计——以经典测试理论和项目反应理论为基础

在总结目前考试测评系统不足的基础上提出科学有效的考试质量评价方法,并在该方法的指导下运用经典测试理论和项目反应理论设计考试质量在线测评系统。系统具有创建新表、成绩统计、质量分析以及基于经典测试理论下的信度和效度分析等功能,能够满足广大教师对考试质量分析的需求。     

NS数据流机制及其解析器实现的研究

分析了NS(network simulator)仿真器的主要元素，介绍了它的结点、链路以及代理对数据流的处理方式和流程，描述了在脚本件中识别和采集数据流的方法．基于仿真结果表示的方法，得到了解析数据流的状态，并构造了相应的转移事件和状态机，实现了针对指定流类型统计网络中任意结点流量的分析器，在一个NS应用中，通过分析器产生了统计结果，证明了该设计的可行性和有效性．