Cardiorespiratory fitness,white blood cell count,and mortality in men and women

Background:We examined the associations of cardiorespiratory fitness(CRF) and white blood cell count(WBC) with mortality outcomes.Methods: A total of 52,056 apparently healthy adults completed a comprehensive health examination,including a maximal treadmill test and blood chemistry analyses.CRF was categorized as high,moderate,or low by age and sex;WBC was categorized as sex-specific quartiles.Results:During 17.8± 9.5 years(mean± SD) of follow-up,a total of 4088 deaths occurred.When regressed jo...     

Cardiorespiratory fitness and telomere length: a systematic review

ABSTRACT

This study aimed to systematically review the association between cardiorespiratory fitness and telomere length (TL). Studies were identified from searches in Cochrane Central, PubMed, Scopus, Sportdiscus, and Web of Science databases through July 2019. Eligibility criteria included: cross-sectional, prospective, and experimental study design; outcomes included TL; results expressed the relationship between cardiorespiratory fitness and TL; studies published in English, Portuguese, or Spanish. A total of 20 articles met the inclusion criteria. Sixteen studies (80%) reported a significant relationship between cardiorespiratory fitness, or training load, and TL. Better cardiorespiratory fitness or a large cardiorespiratory training load are associated with an increase in TL. Although, TL was related to regular moderate-to-vigorous aerobic exercise and cardiorespiratory fitness in older healthy humans, it was not related to cardiorespiratory fitness among young subjects. There seems to be a positive and significant relationship between cardiorespiratory fitness and TL, mainly among middle age and older people, which emphasizes the importance of cardiorespiratory fitness for healthy ageing. Therefore, endurance exercise and better cardiorespiratory fitness may regulate the TL in middle age and older adults, slowing the cellular ageing process.     

Cardiorespiratory fitness in urban adolescent girls: associations with race and pubertal status

Cardiorespiratory fitness affords health benefits to youth. Among females, weight-relative fitness declines during puberty and is lower among African American (AA) than Caucasian girls. Data indicate racial differences in pubertal timing and tempo, yet the interactive influence of puberty and race on fitness, and the role of physical activity (PA) in these associations have not been examined. Thus, independent and interactive associations of race and pubertal development with fitness in adolescent girls, controlling for PA were examined. Girls in grades 5–8 (n = 1011; Caucasian = 25.2%, AA = 52.3%, Other Race group = 22.5%) completed the Pubertal Development Scale (pubertal stage assessment) and Fitnessgram® Progressive Aerobic Cardiovascular Endurance Run (PACER) test (cardiorespiratory fitness assessment). PA was assessed by accelerometry. Bivariate and multivariate analyses were used to examine associations among race, pubertal stage and fitness, controlling for vigorous PA, AA, and pubertally advanced girls demonstrated lower fitness than Caucasian and less mature counterparts. Puberty and race remained significantly associated with fitness after controlling for vigorous PA. The interaction effect of race and puberty on fitness was non-significant. The pubertal influence on fitness is observed among AA adolescents. Associations between fitness and race/puberty appear to be independent of each other and vigorous PA. Pubertally advanced AA girls represent a priority group for fitness interventions.     

Cardiorespiratory and muscular fitness associations with older adolescent cognitive control

Background:Participation in physical activity supports greater cardiorespiratory fitness(CRF),a correlate of cognitive control.However,the relationship between muscular fitness(MF)and cognitive control is less clear.The present study investigated the differential relationship of CRF and MF with cognitive control in older adolescents.Methods:This cross-sectional study involved students(15
17 years old,n=541,43%female)from 20 secondary schools who completed tests of inhibition(modified flanker task),working memory(n-back task),CRF(Progressive Aerobic Cardiovascular Endurance Run),and MF(standing long jump and push-up test).Multilevel analyses tested the association between CRF or MF and cognitive outcomes while accounting for the influence of the other fitness variable and relevant demographic factors.Results:CRF predicted response accuracy during incongruent flanker trials,the condition requiring greater inhibition.For the working memory task,CRF predicted greater target accuracy and greater d’scores on the 1-back task,requiring lesser amounts of working memory.In the 2-back task,which requires greater amounts of working memory,CRF also predicted greater target and non-target accuracy and d’scores.Comparatively,MF did not predict any cognitive outcomes after adjustment for CRF.Conclusion:CRF was selectively related to better performance during task conditions that require greater amounts of inhibition and working memory.This finding suggests that CRF,but not MF,may benefit cognitive control in older adolescents.This selective influence of CRF on older adolescents’cognition highlights the value of aerobic physical activity.     

Psychosocial correlates of cardiorespiratory fitness and muscle strength in overweight and obese post-menopausal women: A MONET study

Abstract

The purpose of this study was to examine the psychosocial correlates of cardiorespiratory fitness ([Vdot]O_2peak) and muscle strength in overweight and obese sedentary post-menopausal women. The study population consisted of 137 non-diabetic, sedentary overweight and obese post-menopausal women (mean age 57.7 years, s = 4.8; body mass index 32.4 kg · m^?2, s = 4.6). At baseline we measured: (1) body composition using dual-energy X-ray absorptiometry; (2) visceral fat using computed tomography; (3) insulin sensitivity using the hyperinsulinaemic-euglycaemic clamp; (4) cardiorespiratory fitness; (5) muscle strength using the leg press exercise; and (6) psychosocial profile (quality of life, perceived stress, self-esteem, body-esteem, and perceived risk for developing chronic diseases) using validated questionnaires. Both [Vdot]O_2peak and muscle strength were significantly correlated with quality of life (r = 0.29, P < 0.01 and r = 0.30, P < 0.01, respectively), and quality of life subscales for: physical functioning (r = 0.28, P < 0.01 and r = 0.22, P < 0.05, respectively), pain (r = 0.18, P < 0.05 and r = 0.23, P < 0.05, respectively), role functioning (r = 0.20, P < 0.05 and r = 0.24, P < 0.05, respectively), and perceived risks (r = ?0.24, P < 0.01 and r = ?0.30, P < 0.01, respectively). In addition, [Vdot]O_2peak was significantly associated with positive health perceptions, greater body esteem, and less time watching television/video. Stepwise regression analysis showed that quality of life for health perceptions and for role functioning were independent predictors of [Vdot]O_2peak and muscle strength, respectively. In conclusion, higher [Vdot]O_2peak and muscle strength are associated with a favourable psychosocial profile, and the psychosocial correlates of [Vdot]O_2peak were different from those of muscle strength. Furthermore, psychosocial factors could be predictors of [Vdot]O_2peak and muscle strength in our cohort of overweight and obese sedentary post-menopausal women.     

Cardiorespiratory fitness measured with cardiopulmonary exercise testing and mortality in patients with cardiovascular disease: A systematic review and meta-analysis

BackgroundCardiorespiratory fitness (CRF) is inversely associated with mortality in apparently healthy subjects and in some clinical populations, but evidence for the association between CRF and all-cause and/or cardiovascular disease (CVD) mortality in patients with established CVD is lacking. This study aimed to quantify this association.MethodsWe searched for prospective cohort studies that measured CRF with cardiopulmonary exercise testing in patients with CVD and that examined all-cause and CVD mortality with at least 6 months of follow-up. Pooled hazard ratios (HRs) were calculated using random-effect inverse-variance analyses.ResultsData were obtained from 21 studies and included 159,352 patients diagnosed with CVD (38.1% female). Pooled HRs for all-cause and CVD mortality comparing the highest vs. lowest category of CRF were 0.42 (95% confidence interval (95%CI): 0.28–0.61) and 0.27 (95%CI: 0.16–0.48), respectively. Pooled HRs per 1 metabolic equivalent (1-MET) increment were significant for all-cause mortality (HR = 0.81; 95%CI: 0.74–0.88) but not for CVD mortality (HR = 0.75; 95%CI: 0.48–1.18). Coronary artery disease patients with high CRF had a lower risk of all-cause mortality (HR = 0.32; 95%CI: 0.26–0.41) than did their unfit counterparts. Each 1-MET increase was associated with lower all-cause mortality risk among coronary artery disease patients (HR = 0.83; 95%CI: 0.76–0.91) but not lower among those with heart failure (HR = 0.69; 95%CI: 0.36–1.32).ConclusionA better CRF was associated with lower risk of all-cause mortality and CVD. This study supports the use of CRF as a powerful predictor of mortality in this population.     

Psychosocial correlates of cardiorespiratory fitness and muscle strength in overweight and obese post-menopausal women: a MONET study

The purpose of this study was to examine the psychosocial correlates of cardiorespiratory fitness (VO2peak) and muscle strength in overweight and obese sedentary post-menopausal women. The study population consisted of 137 non-diabetic, sedentary overweight and obese post-menopausal women (mean age 57.7 years, s = 4.8; body mass index 32.4 kg.m(-2), s = 4.6). At baseline we measured: (1) body composition using dual-energy X-ray absorptiometry; (2) visceral fat using computed tomography; (3) insulin sensitivity using the hyperinsulinaemic-euglycaemic clamp; (4) cardiorespiratory fitness; (5) muscle strength using the leg press exercise; and (6) psychosocial profile (quality of life, perceived stress, self-esteem, body-esteem, and perceived risk for developing chronic diseases) using validated questionnaires. Both VO2peak and muscle strength were significantly correlated with quality of life (r = 0.29, P < 0.01 and r = 0.30, P < 0.01, respectively), and quality of life subscales for: physical functioning (r = 0.28, P < 0.01 and r = 0.22, P < 0.05, respectively), pain (r = 0.18, P < 0.05 and r = 0.23, P < 0.05, respectively), role functioning (r = 0.20, P < 0.05 and r = 0.24, P < 0.05, respectively), and perceived risks (r = -0.24, P < 0.01 and r = -0.30, P < 0.01, respectively). In addition, VO2peak was significantly associated with positive health perceptions, greater body esteem, and less time watching television/video. Stepwise regression analysis showed that quality of life for health perceptions and for role functioning were independent predictors of VO2peak and muscle strength, respectively. In conclusion, higher VO2peak and muscle strength are associated with a favourable psychosocial profile, and the psychosocial correlates of VO2peak were different from those of muscle strength. Furthermore, psychosocial factors could be predictors of VO2peak and muscle strength in our cohort of overweight and obese sedentary post-menopausal women.     

Cardiorespiratory fitness,fatness, and cardiovascular disease risk factors in children and adolescents from Porto

Abstract

In the present study, we examined different categories of cardiorespiratory fitness and obesity and their relationship with risk of cardiovascular disease (CVD) factors in youth. We hypothesized that youngsters with low cardiorespiratory fitness would be at greater risk of CVD risk factors, whether they are obese or not. This study was carried out as a part of a longitudinal research project conducted in the Porto and Braga districts, Portugal, with children and adolescents aged 10–16 years of age. A total of 392 children (173 boys, 219 girls) participated in the study. We used a chi-square test to analyse the relationship between the participants' cardiorespiratory fitness and body weight (non-overweight or overweight/obese). For the purpose of this study, a new variable with four groups was created: non-overweight +unfit (37.4%), non-overweight + fit (35%), overweight/obese + unfit (11%) and overweight/obese + fit (10%). A one-way analysis of variance was used to compare the differences according to fitness and fatness groups. The main finding of this study was that regardless of fatness, participants with higher cardiorespiratory fitness presented with a lower prevalence of CVD risk factors.     

Adverse associations of sedentary behavior with cancer incidence and all-cause mortality: A prospective cohort study

BackgroundInconsistent results have been reported in developed countries for relationships between sedentary behavior and cancer incidence and mortality, and evidence from the Chinese population is scarce. This study aimed to investigate such relationships in large Chinese population-based prospective cohorts and to explore the joint effect and interaction of sedentary behavior and moderate-to-vigorous physical activity (MVPA) on these relationships.MethodsWe included 95,319 Chinese adults without cancer from 3 large cohorts and assessed their sedentary behavior and physical activity with a unified questionnaire. Cancer incidence and mortality were confirmed by interviewing participants or their proxies and checking hospital records and death certificates. Hazard ratios (HRs) and 95% confidence intervals (95%CIs) for cancer and mortality were estimated using Cox proportional hazards regression models.ResultsDuring 559,002 person-years of follow-up, 2388 cancer events, 1571 cancer deaths, and 4562 all-cause deaths were recorded. Sedentary behavior was associated with increased risk of developing cancer and deaths in a dose–response manner. The multivariable-adjusted HRs (95%CIs) were the following: HR = 1.16, 95%CI: 1.01‒1.33; HR = 1.24, 95%CI: 1.04‒1.48; and HR = 1.15, 95%CI: 1.04‒1.28 for cancer incidence, cancer mortality, and all-cause mortality, respectively, for those having ≥10 h/day of sedentary time compared with those having <6 h/day of sedentary time. Sedentary populations (≥10 h/day) developed cancer or died 4.09 years and 2.79 years earlier, respectively, at the index age of 50 years. Failure to achieve the recommended level of MVPA may further aggravate the adverse associations, with the highest cancer and mortality risks being observed among participants with both ≥10 h/day of sedentary time and <150 min/week of MVPA. Limitations of this study include the fact that physical activity information was obtained via questionnaire instead of objective measurement and that there were insufficient incident cases for the analysis of associations between sedentary behavior and site-specific cancers.ConclusionSedentary behavior was associated with an increased risk of cancer and all-cause mortality among Chinese adults, especially for those with ≥10 h/day of sedentary time. It is necessary to reduce sedentary time, in addition to increasing MVPA levels, for the prevention of cancer and premature death.     

Cardiorespiratory fitness and arm bone mineral health in young males with spinal cord injury: the mediator role of lean mass

Spinal cord injury (SCI) derives in loss of bone mineral content (BMC) and bone mineral density (BMD). However, physical activity is an important determinant in bone mass acquisition, which is partially mediated through the lean mass (LM). The aim was to examine the effect of cardiorespiratory fitness (CRF) on BMD and BMC arms of adult males with SCI and able-bodied controls using the arm LM as a mediator variable. Thirty able-bodied men and thirty men with SCI participated. BMC and BMD were analysed by DXA, and indirect calorimetry was used to calculate VO_2peak during a progressive arm-cranking test. When groups were divided by the amount of LM, the subgroup with highest LM had significantly higher arm BMC compared to the lowest LM subgroup (p ≤ 0.05) in both SCI and able-bodied groups. Moreover, same differences were found when confidence intervals were analysed. Only in the SCI group, arm LM mediated the relationship between bone mass and CRF at 30.9%, as indicated by the Sobel test (z = 2.17 and z = 2.04 for BMC and BMD, respectively). In conclusion, LM mediates the indirect association between CRF and bone health, specifically in the arms. This finding highlights the importance of having an adequate CRF for the maintenance of good bone health in SCI men.     

Factors associated with muscular fitness phenotypes in Australian children: A cross-sectional study

ABSTRACT

To help inform strategies aimed at increasing muscular fitness levels, we examined factors associated with childhood muscular fitness (strength and power) that preceded the recently observed secular decline. Data were available from a nationally representative sample of Australian children aged 7–15 years in 1985 (n = 8469). Muscular fitness measures included strength (right and left grip, shoulder extension and flexion, and leg strength) and power (standing long jump distance). Anthropometric (adiposity, fat-free mass), cardiorespiratory fitness (CRF), flexibility, speed capability, physical activity (individual and parental), dietary quality and intake (fruit, vegetable, protein) and sociodemographic (area-level socioeconomic status (SES), school type) data were available. Statistical analyses included sex-stratified linear regression. Of all examined factors, measures of adiposity, fat-free mass, CRF, flexibility and speed capability were associated with muscular fitness at levels that met Cohen’s threshold for important effects (r-squared = 0.02 to 0.28). These findings highlight the multifactorial relationship between muscular fitness and its determinants. Collectively, these factors were powerful in explaining muscular strength (females: r-squared = 0.32; males: r-squared = 0.41) and muscular power (females: r-squared = 0.36; males: r-squared = 0.42). These findings highlight modifiable and environmental factors that could be targeted to increase childhood muscular fitness.     

Sleep quantity and quality in elite youth soccer players: A pilot study

This study examined the effect of early evening high-intensity training on the sleep of elite male youth soccer players (n = 12) using wrist actigraphy. High-intensity training (TRAIN) nights were compared with a home environment (HOME) condition, created by averaging sleep variables on the night before and after TRAIN nights. Additionally, after TRAIN athletes alternately used cold water immersion (TRAIN+CWI) or none, to assess whether cold water immersion (CWI) had any impact on sleep quality and quantity. Ratings of perceived exertion, fatigue and recovery were recorded after training. Actigraphy sleep measures were bedtime, wake time, sleep duration, sleep onset latency, sleep efficiency and wake after sleep onset. Self-rated scores of sleepiness at bedtime and wake, plus overall sleep quality were also recorded. Only fatigue ratings were higher in TRAIN compared to TRAIN+CWI at bedtime, there were no other differences in training data. Both TRAIN and TRAIN+CWI conditions had significant later (07:45 ± 1:09 h p < 0.01 and 07:34 ± 1:20 h p = 0.01) wake times than HOME (06:44 ± 0:41 h). The TRAIN condition had a significantly higher (7 ± 2; p < 0.01) rating of sleepiness at bedtime compared to HOME (6 ± 1), but no further differences were found in any of the sleep (actigraphy and self-reported) measures. Across all conditions, time spent asleep was ～7:30 (±0:52) h:min and sleep efficiency was ～89% (±6.1). In conclusion, early evening high-intensity training had no impact on subsequent sleep quality and quantity, nor was there any effect on sleep after performing CWI post-training.     

中年女子水中运动的健身效果

通过对西安市中年女子进行8周水中健身减脂效果的分析表明:经过水中健身锻炼,实验组与对照组BMI、腹部和大腿部减脂效果明显(P<0.05),上臂部、肩胛部等不明显(P>0.05),为中年女子较为关心的如何轻松减肥提供依据。     

Epidemiology of insertional and midportion Achilles tendinopathy in runners:A prospective cohort study

Background:Achilles tendinopathy(AT) is a common problem among runners.There is only limited evidence for risk factors for AT,and most studies have not defined the AT subcategories.No study has compared the incidence and risk factors between insertional AT and midportion AT,though they are considered distinct.This study aimed to assess incidence and risk factors of AT based on data from a large prospective cohort.The secondary aim was to explore differences in risk factors between insertional an...     

广州市社区实施全民健身工程的现状与对策

广州市民的体育健身意识强；全民健身工程得到广州市民的普遍欢迎，改善了人民群众的强身健体的条件；社区全民健身工程的场地、器材的配建及资金投入逐步完善；指出了实施全民健身工程中的问题;提出了未来发展的相应对策。     

Number of parous events affects the association between physical exercise and glycemic control among women with gestational diabetes mellitus: A prospective cohort study

Background:Multiparous women are at a higher risk of gestational diabetes mellitus(GDM) than primiparas.Physical activity during pregnancy has been shown to be beneficial for GDM,but there is little evidence on the association between physical activity and glycemic control among women with GDM,whether primiparas or multiparas.Thus,the objective of the present study was to examine the association between physical activity and glycemic control in women with GDM and to determine what,if any,effects...     

武汉市妇女弱势群体对健身项目的选择及其影响因素

运用文献资料法、问卷调查法、数理统计法与逻辑分析法等方法,对武汉市妇女弱势群体（工人、离退休、下岗、家庭妇女四种群体）进行健身项目选择与影响因素进行调查研究。结论：武汉市妇女弱势群体参与体育锻炼以直接参与为主;在年龄上以青年和老年居多;文化程度偏低;身体状况较差;锻炼项目选择比较单一但群体性比较强;体育消费支出少;信息获取渠道单一;所接受的健身方面的指导较少。结合影响其参与锻炼的因素,提出有针对性的建议,为武汉市妇女弱势群体的健身提供参考。     

Association of physical fitness and fatness with cognitive function in women with fibromyalgia

This study assessed the association of fitness and fatness with cognitive function in women with fibromyalgia, and the independent influence of their single components on cognitive tasks. A total of 468 women with fibromyalgia were included. Speed of information processing and working memory (Paced Auditory Serial Addition Task), as well as immediate and delayed recall, verbal learning and delayed recognition (Rey Auditory Verbal Learning Test) were assessed. Aerobic fitness, muscle strength, flexibility and motor agility were assessed with the Senior Fitness Test battery. Body mass index, percent body fat, fat-mass index and waist circumference were measured. Aerobic fitness was associated with attention and working memory (all, p < 0.05). All fitness components were generally associated with delayed recall, verbal learning and delayed recognition (all, p < 0.05). Aerobic fitness showed the most powerful association with attention, working memory, delayed recall and verbal learning, while motor agility was the most powerful indicator of delayed recognition. None of the fatness parameters were associated with any of the outcomes (all, p > 0.05). Our results suggest that fitness, but not fatness, is associated with cognitive function in women with fibromyalgia. Aerobic fitness appears to be the most powerful fitness component regarding the cognitive tasks evaluated.     

Sleep quality improved following a single session of moderate-intensity aerobic exercise in older women: Results from a pilot study

BackgroundPoor sleep quality is associated with adverse effects on health outcomes. It is not clear whether exercise can improve sleep quality and whether intensity of exercise affects any of the effects.MethodsFifteen healthy, non-obese (body mass index = 24.4 ± 2.1 kg/m², mean ± SD), sedentary (<20 min of exercise on no more than 3 times/week) older women (66.1 ± 3.9 years) volunteered for the study. Peak oxygen consumption (VO_2peak) was evaluated using a graded exercise test on a treadmill with a metabolic cart. Following a 7-day baseline period, each participant completed two exercise sessions (separated by 1 week) with equal caloric expenditure, but at different intensities (60% and 45% VO_2peak, sequence randomized) between 9:00 and 11:00 am. A wrist ActiGraph monitor was used to assess sleep at baseline and two nights following each exercise session.ResultsThe average duration of the exercise was 54 and 72 min, respectively at 60% (moderate-intensity) and 45% VO_2peak (light-intensity). Wake time after sleep onset was significantly shorter (p = 0.016), the number of awakenings was less (p = 0.046), and total activity counts were lower (p = 0.05) after the moderate-intensity exercise compared to baseline no-exercise condition.ConclusionOur data showed that a single moderate-intensity aerobic exercise session improved sleep quality in older women.