中国兜被兰属植物的研究

兰科的兜被兰属约有12种，主要分布于亚洲的温带至亚热带山地，我国的四川和云南是其现代分布中心和分化中心。本文通过植物地理学、孢粉学和解剖学的研究，对该属进行分类学订正，确认中国产有12种，其中9种为我国特有，包括4个新种和1个新组合种。     

芍药属牡丹组分类新注

自我们近年发表一系列牡丹组分类文章以来, 国内外基本上赞同我们8个种的分类系统,但对一些问题仍有不同见解。本文进一步申述牡丹Paeonia suffruticosa Andrews 是一个独立的种而不是人工杂种, 以及银屏牡丹P. suffruticosa ssp. yinpingmudan是牡丹P. suffruticosa的野生类型而不是逸生的P. ostii的理由。上述论点也得到了分子树的支持。P. jishanensis T. Hong & W. Z. Zhao是一个合法名称, 而P. spontanea (Rehder) T. Hong & W. Z. Zhao则确实是一个多余名。太白山紫斑牡丹的学名应是P. rockii ssp. atava (Brühl) D. Y. Hong & K. Y. Pan, 因此P. moutan Sims ssp. atava Brühl不应是可疑的分类群。本文还对Halda的6个组合和两个杂交种名作了处理。结果, 本文包括了5个新异名和一个新组合。     

中国苦苣苔科的研究(九）

Ten new species, three new varieties and a new section of the family Ge- sneriaceae are described from China in the present paper.   They are Tremacron urceolatum K. Y. Pan from Muli of SW Sichuan, T. obliquifolium K. Y. Pan from Miyi and Yanyuan of SW Sichuan, T. aurantiacum K. Y. Pan from Mabian and Pinshan of S Sichuan, lsometrum Sect.  Chorianthera W. T. Wang et K. Y. Pan (with I. eximium Chun as the section type), Isometrum eximium Chun ex K. Y. Pan from Jiulong, Muli  and  Jinyang  of  SW  Sichuan; Ancylostemon mairei (Levl.) Craib var. emeiensis K. Y. Pan from Mt. Emei of Sichuan, A. aureus (Franch.)  Burtt var. angustifolius K. Y. Pan from Zhenkang of SW Yunnan, A. ga- mosepalus K. Y. Pan from Hanyuan, Yanyuan and Yuexi of SW Sichuan, A. rhombifolius K. Y. Pan from Meigu of SW Sichuan, A. ronganensis K. Y. Pan from Rong an of Guangxi; Corallodiscus flabellatus) (Craib) Burtt var. puberulus K.Y. Pan from Zhongdian and Deqin of NW Yunnan, Nanchuan of S Sichuan and Zayü of Xizang (Tibet), Beccarinda minima K. Y. Pan from Jinxiu and Xiangzhou of Guangxi, Boeica stolonifera K. Y. Pan from Fang- cheng, Shiwandashan, Pingnan and Dongxing of S Guangxi, B. multinervia K. Y. Pan from Yingjiang of W Yunnan, and Paraboea barbatipes K. Y. Pan from Napo of W Guangxi and Xichou of SE Yunnan.     

中国粗筒苣苔属(苦苣苔科)新分类群

Ten new species, three new varieties and a new section of the family Ge- sneriaceae are described from China in the present paper.   They are Tremacron urceolatum K. Y. Pan from Muli of SW Sichuan, T. obliquifolium K. Y. Pan from Miyi and Yanyuan of SW Sichuan, T. aurantiacum K. Y. Pan from Mabian and Pinshan of S Sichuan, lsometrum Sect.  Chorianthera W. T. Wang et K. Y. Pan (with I. eximium Chun as the section type), Isometrum eximium Chun ex K. Y. Pan from Jiulong, Muli  and  Jinyang  of  SW  Sichuan; Ancylostemon mairei (Levl.) Craib var. emeiensis K. Y. Pan from Mt. Emei of Sichuan, A. aureus (Franch.)  Burtt var. angustifolius K. Y. Pan from Zhenkang of SW Yunnan, A. ga- mosepalus K. Y. Pan from Hanyuan, Yanyuan and Yuexi of SW Sichuan, A. rhombifolius K. Y. Pan from Meigu of SW Sichuan, A. ronganensis K. Y. Pan from Rong an of Guangxi; Corallodiscus flabellatus) (Craib) Burtt var. puberulus K.Y. Pan from Zhongdian and Deqin of NW Yunnan, Nanchuan of S Sichuan and Zayü of Xizang (Tibet), Beccarinda minima K. Y. Pan from Jinxiu and Xiangzhou of Guangxi, Boeica stolonifera K. Y. Pan from Fang- cheng, Shiwandashan, Pingnan and Dongxing of S Guangxi, B. multinervia K. Y. Pan from Yingjiang of W Yunnan, and Paraboea barbatipes K. Y. Pan from Napo of W Guangxi and Xichou of SE Yunnan.     

中国绞股蓝属(葫芦科)的研究

 The genus Gynostemma B1. consists of 13 species and 2 varieties in the whole world, among which 11 species and 2 varieties occur in China. They are distributed in S. Shaanxi and the southern part of the Yangtze River (including Taiwan province) in China and also in Korea, Japan, Sri Lanka, India and Malesia. Based on the characters and dehiscence of fruit, the genus Gynostemma B1. may be divided into two subgenera, i.e. Subgen. I. Gynostemma and Subgen. II. Trirostllum (Z. P. Wang et Q. Z. Xie) C. Y. Wu ct S. K. Chen, comb. nov.        1.  Subgenus Gynostemma. The fruits are baccate, globose, 3-umbonate and incorni culate on the apical side, indehiscent when mature. The style apex in female flower is bifid.       Type of subgenus: Gynostemma pentaphyllum (Thunb.) Mak.       This subgenus contains 8 species and 2 varieties in the world, among which 6 speci- es and 2 varieties occur in China, i.e.1.G. simplicifolium B1. (Yunnan, Hainan of Guang- dong); 2. G. laxum (Wall.) Cogn. (S. Yunnan, Hainan of Guangdong and Guangxi); 3. G. burmanicum King ex Chakr. (Yunnan), 3a. G. burmanicum var. molle C. Y. Wu (Yun- nan); 4. G. pentaphyllum (Thunb.) Mak. (S. Shaanxi and the soutern area of the Yangtze River of China), 4a. G. pentaphyllum (Thunb.) Mak. var. dasycarpum C. V. Wu (Yun- nan); 5. G. pubescens (Gagnep.) C. Y. Wu, st. nov. (Yunnan); 6. G. longipes C. Y. Wu, sp. nov. (endemic to China: Yunnan, Sichuan, Guizhou, Shaanxi and Guangxi).       2.  Subgenus Trirostellum (Z. P. Wang et Q. Z. Xie) C. Y. Wu et S. K. Chen, comb. nov.——Trirostellum Z. P. Wang et Q. Z. Xie in Acta Phytotaxonomia Sinica 19 (4): 483. 1981, syn. nov. The fruit are capsules, subcampanulate, 3-corniculate on the apical side, dehiscent when mature. The style apex in female flower is luniform and irregularly denticulate at margin, rarely bifid.       Type of subgenus: Gynostemma cardiospermum Cogn. ex Oliv.      This subgenus comprises 5 species, which are all endemic to China.  1. G. yixingense (Z. P. Wang et Q. Z. Xie) C. Y. Wu et S. K. Chen (Jiangsu and Zhejiang); 2. G. cardio spermum Cogn. ex Oliv. (Hubei, Shaanxi and Sichuan); 3. G. microspermum C. Y. Wu et S. K. Chen (S. Yunnan); 4. G. aggregatum C. Y. Wu et S. K. Chen (NW. Yunnan); 5. G.laxiflorum C. Y. Wu et S. K. Chen (Anhui).     

芍药属牡丹组分类补注

把沈保安2001年发表的6个新组合和新等级处理为异名,这些异名是Paeonia linyanshanii (S. G. Haw & L. A. Lauener) B. A. Shen (不合法名),P. linyanshanii ssp. taibaishanica (D. Y. Hong) B. A. Shen (不合法名),P. ostii T. Hong & J. X. Zhang ssp. lishizhenenii (lishizhenii) (B. A. Shen) B. A. Shen (=P. ostii), P. delavayi Franch. ssp. angustiloba (Rehder & E. H. Wilson) B. A. Shen 和ssp. lutea (Delavay ex Franch.) B. A. Shen (=P. delavayi)以及P. delavayi ssp. ludlowii (Stern & Taylor) B. A. Shen (=P. ludlowii (Stern & Taylor) D. Y. Hong)。     

The twin-beginnings of COVID-19 in Asia and Europe—one prevails quickly

In the spread of SARS-CoV-2, there have been multiple waves of replacement between strains, each of which having a distinct set of mutations. The first wave is a group of four mutations (C241T, C3037T, C14408T and A23403G [this being the amino acid change D614G]; all designated 0 to 1 below). This DG (D614G) group, fixed at the start of the pandemic, is the foundation of all subsequent waves of strains. Curiously, the DG group is absent in early Asian samples but present (and likely common) in Europe from the beginning. European data show that the high fitness of DG1111 requires the synergistic effect of all four mutations. However, the European strains would have had no time to evolve the four DG mutations (0 to 1), had they come directly from the early Asian DG0000 strain. Very likely, the European DG1111 strain had acquired the highly adaptive DG mutations in pre-pandemic Europe and had been spreading in parallel with the Asian strains. Two recent reports further support this twin-beginning interpretation. There was a period of two-way spread between Asia and Europe but, by May 2020, the European strains had supplanted the Asian strains globally. This large-scale replacement of one set of mutations for another has since been replayed many times as COVID-19 progresses.     

菊科新资料

记述了菊科6个属的一些新分类群和新分布，包含1个新组、3个新种、3个新变种、1个新名称、1个新组合和5个种的新记录。这些新分类群是黄鹌菜属蓝舌组、振铎黄鹌菜、蓝花黄鹌菜、青海乳苣、黄苞垂头菊、尼泊尔橐吾和半裂橐吾。     

南亚和东南亚龙胆属(龙胆科)的新名称、新组合及分类注释

本文提出了龙胆属两个种的新名称(Gentiana membranulifera T．N．Ho,G．nudicaulisKurz var. assa- mensis T．N．Ho)和5个变种的新组合[(Gentiana lateriflora Hemsl．var. uncifolia(H．J．Lam)T．N．Ho, G．sumatrana Ridl．var．humifusa(S．Moore)T．N．Ho,G. quadrifaria Bl．var．wightii(Kusnez．)T．N．Ho, G．loerzingii Ridl. var．timida(Kerr)T．N．Ho,G．membranulifera T．N．Ho var．recurvata (Kusnez．)T．N．Ho)〕。     

中国拟兰亚科的研究

Apostasioideae, a small subfamily of Orchidaceae, is largely distributed in tropical Asia with its northern limit extending to the Ryukyu Islands and south China. The first Chinese species of this subfamily was reported by E. D. Merrill (1927) based on a specimen collected from Hainan (McClure 9519, AMES), which he regarded as Apostasia wallichii R. Br. As later labelled by E. F. de Vogel, it is in fact identical with A. odorata Bl., a widespread spe- cies also found in southern Guangdong, Guangxi and Yunnan of China.  It was not until re- cently that the true A. wallichii was collected from southwestern Yunnan bordering on Burma, which is initially reported here.  In addition, an interesting new species, A. ramifera S. C. Chen et K. Y. Lang, is described from Hainan.       The only Chinese species of Neuwiedia has long been known as N. veratrifolia Bl. (of. Iconographia Cormophytorum Sinicorum 5: 602, t. 8034. 1976, and Flora Hainanica 4 180, t. 1078. 1977), which, however, was considered by de Vogel (1969) to be not found in China.  In de Vogel's revision, no Chinese taxon but a variety, N. zollingeri Rchb. f. var. singapureana (Baker) de Vogel, is cited with some doubt based on a specimen of Hainan (F. C. How 73122, in young fruit, AMES). N. zollingeri var. singapureana is in fact quite different from N. veratrifolia by having glandular hair, much shorter inflorescence and flattened filaments.  As recently pointed out by de Vogel and G. Barretto (in Journ. Taiwan Museum 37: 78. 1984), the plants found in Hongkong, as well as those in Guangdong and Yunnan, possess glandular hair and short inflorescence. They are identical with the Vietnamese species N. balansae Gagnep., which was reduced by de Vogel to a synonym of N. zollingeri var singapureana. E. F. de Vogel's suggestion seems to be acceptable except the varietal rank.  It is treated here as a se- parate species, N. singapureana (Baker) Rolfe, according to its fruit and hair characters.  Thus we have altogether one species of Neuwiedia and three species of Apostasia in China, including a new species and a newly recorded one.     

Role of HAMP Genetic Variants on Pathophysiology of Iron Deficiency Anemia

Hepcidin is a 25-amino acid peptide hormone produced by hepatocytes and plays a key role in body iron metabolism. Hepcidin deficiency is the cause of iron overload in hereditary hemochromatosis, iron-loading anemia, and its excess is associated with anemia of inflammation, chronic disease and iron deficiency anemia (IDA). The aims of this study was to evaluate HAMP gene mutation, namely IVS2 + 1(–G) (c.148–150 + 1del) and Gly71 Asp (c.212G > A (rs104894696) association with iron status in IDA conditions. Our study participants were 500 IDA patients and 550 age and sex-matched healthy controls. Hepcidin, ferritin and CRP analysis was done by ELISA method while ESR analysis was done according to Wintrobe method. CBC analysis was done by auto-analyzer. Two mutations in the HAMP genes were analysed by PCR RFLP method. Among the IDA patients, 7 were heterozygous for Met50del IVS2 + 1(–G) mutation. Nine IDA patients were heterozygous for G71D G–A mutation and homozygous were not identified in both mutations.Controls were showing heterozygous frequency 1.8 and 2.1% of Met50del IVS2 + 1(–G) and G71D G–A mutations respectively. Mutation of HAMP (Met50del IVS2 + 1(–G) and G71D G–A) were clinically associated with IDA and act as modulator of disease.     

异枝竹属的名实问题

 将异枝竹属Metasasa W．T. Lin作为酸竹属Acidosasa C．D．Chu et C．S．Chao ex Keng f．的异名处 理。异枝竹Metasasa carinata W．T. Lin和白环异枝竹 Metasasa albo-farinosa W．T．Lin作为新组合名Aci-dosasa nanunica(McCl．)C．S．Chao et G．Y．Yang，comb．nov．的异名。     

一个含临界指数的拟线性椭圆型方程的注记

研究了如下的拟线性椭圆型方程:△pu+uq+λup*-1=0,u∈W1o,p(Ω), (1λ)其中,Ω2是RN中具有光滑边界的有界区域,△pu=div( |▽u|p-2▽u),N≥3,2≤p＜N,0＜q＜1,p*=NP/N-P.设λ*(Ω,p,q)是拟线性椭圆型方程(1λ)可解的参数集的上确界.运用变分方法,在不要求具有对称性质的一般区域Ω上得到了λ*(Ω,p,q)的一个可以精确计算的下界.     

Association of Aberrations in One Carbon Metabolism with Intimal Medial Thickening in Patients with Type 2 Diabetes Mellitus

The present work was aimed to study the association of one carbon genetic variants, hyperhomocysteinemia and oxidative stress markers, i.e., serum nitrite, plasma malondialdehyde (MDA) and glutathione (GSH) on intimal medial thickening (IMT) in patients with type 2 diabetes mellitus (T2D). A total number of 76 subjects from ACS Medical College and Hospital, Chennai, India were included in the study, i.e., Group I (n = 42) of T2D and Group II (n = 34) of age- and sex matched healthy controls. The glycated haemoglobin was measured by ion-exchange resin method; plasma homocysteine by Enzyme Linked Immunosorbant Assay method; serum nitrite (nitric oxide, NO), plasma MDA and GSH by spectrophotometric methods; the IMT by high frequency ultrasound. The polymorphisms of one carbon genetic variants were genotyped using polymerase chain reaction-restriction fragment length polymorphism and amplified fragment length polymorphism methods. Results indicate that methyltetrahydrofolate homocysteine methyl transferase (MTR) A2756G allele was found to be protective in T2D and the other variants were not significantly associated with T2D. Glutamate carboxypeptidase II (GCP II) C1561T (r = 0.34; p = 0.05) and methylene tetrahydrofolate reductase (MTHFR) C677T (r = 0.35; 0.04) showed positive correlation with plasma homocysteine in T2D cases. In this study, MTR A2756G allele was found to be protective in T2D; GCP II C1561T and MTHFR C677T showed positive association with plasma homocysteine in T2D cases. Among all the genetic variants, MTR A2756G was found influence IMT. RFC 1 G80A and TYMS 5′-UTR 2R3R showed synergistically interact with MTR A2756G in influencing increase in IMT.     

中国杜英属的一些分类问题

本文根据最新研究结果，对国产杜英属植物进行了清理。这里报道的是对《中国植物志》 49(1)杜英属的修订和补充。它包括：(1)纠正3个错误鉴定：Elaeocarpus rugosus Poxb．=E． apiculatus sensu Merr.；E.sikkimensis Mast.=E.fleuryi sensu H.T.Chang；E.decandrus Merr.=E.chinensis sensu H.T.Chang pro parte。 (2)  发表1个新种和1个新变种：E． limitaneioides Y.Tang；E.glabripetalus Merr．var．grandifructusy．Tang．  (3)归并了4种2 变种：E．boreali-yunnanensis H．T．Chang归并为E．lacunosus Wall. ex Kurz，E.floribundioides H．T．Chang归并到E．austro-yunnanensis Hu，E.fengjieensis P.C.Tuan归并至E．duclouxii Gagnep．，E．kwangsiensis H．T．Chang归并为E.glabripetalus Merr. var．alatus(Knuth) H. T. Chang，E. glabripetalus Merr. var．teres H.T.H.T.Chang归并为E.glabripetalus var．glabripetalus，E.prunifolioides Hu var．rectinervis H.T.Chang归并至E.prunifolioidesHu。  (4)报道了一些省级分布新记录；并简单讨论了属下系统。     

蜘蛛抱蛋属的细胞分类学研究Ⅱ

文章报道了13种蜘蛛抱蛋属植物的染色体核型，并对属内核型进化规律作了总结。作者认为随体染色体和第1对染色体可以作为本属核型的特征染色体。染色体数目变异与花部式样密切相关。本属植物原始的染色体基数为x=19。此外，对非整倍性变异的主要机制也进行了讨论。     

中国石竹科石头花属二新种

 Gypsophila huashanensis Y. W. Tsui et D. Q. Lu and G. spinosa D. Q. Lu (Caryophyllaceae) are described as new from China.     

Study of mutations in p53 tumour suppressor gene in human sporadic breast cancers

Using Polymerase Chain Reaction followed by Single Strand Conformation Polymorphism analysis, we studied thirty seven cases of primary human breast cancer for the presence of mutations in exons 5 and 7 of p53 tumour suppressor gene. Only one of the thirty seven tumours tested (2.7%) showed the electrophoretic mobility shift indicative of a mutation in exon 5 of the p53gene, while no such mobility shift was noted in exon 7. Our finding is in contrast to the findings in previous studies, wherein the mutation frequency has been reported to be 13–30% by direct DNA analysis. This may be related to the ethnicity and local population prevalence rather than technique.     

东亚和南亚马兜铃属的补订

作者近期检查了英国三个大标本馆(BM，E，K)所收藏的马兜铃属标本，发现《东亚和南亚马兜铃属的修订》(见本刊27(5)：321—364，1989)尚有不完备之处，需作补充修订。本文共收载8种，其中1新名，确定了1个存疑种，补充了1个种的描述，修改了1个种的模式记载，合并了1个种，扩大了4个种的地理分布。