Relationship of Brain-Derived Neurotrophic Factor with Interleukin-23, Testosterone and Disease Severity in Schizophrenia

Hormonal imbalance, inflammation and alteration in synaptic plasticity are reported to play a crucial role in the pathogenesis of schizophrenia. The objective of the study was to assess the serum levels of brain derived neurotrophic factor (BDNF) and its association with interleukin-23 (IL-23), testosterone and disease severity in schizophrenia. 40 cases and 40 controls were included in the study. Serum levels of BDNF, IL-23 and testosterone were estimated in all the subjects. Disease severity was assessed using Positive and Negative Syndrome Scale (PANSS). The study was designed in Tertiary care hospital, South India. The results were compared between two groups using Mann–Whitney U test. Spearman Correlation analysis was used to assess the association between biochemical parameters and PANSS. Interleukin-23 and testosterone were significantly increased and BDNF was significantly reduced in schizophrenia cases when compared with controls. BDNF was negatively correlated with IL-23 (r = − 400, p = 0.011), positive symptom subscale (r = − 0.393, p = 0.012), general psychopathology score subscale (r = − 407, p = 0.009) and total symptom subscale (r = − 404, p = 0.010). There was no significant association of IL-23 and testosterone with disease severity in schizophrenia cases. BDNF was reduced in schizophrenia cases and negatively associated with interleukin-23 and disease severity scores.     

基于吉林省调研的农民创新活动影响因素分析

为了解农民创新实践活动的影响因素,在深度访谈基础上,综合个体创新与农民创新问题相关研究成果,通过问卷调查方式,采用二元Logistic模型对来自吉林省农民的231份调查问卷进行回归分析。主要了解个体特征、环境特征对农民创新实践活动的影响,从中寻求农村创新体系建设的可行策略。研究结果表明农民创新实践活动与其打工经历、年龄、家庭年收入、住房等情况呈显著正相关;与其家庭人口数呈现显著负相关;与其受教育程度、政府政策支持及当地企业作用无显著相关性。由此可见,农民创新还处于自发萌动期,需要更进一步的制度性建设以利于这一群体的创新实践活动大规模展开。     

技术转移要素初探

本文通过研究、分析国内外技术转移情况,探讨技术转移的要素及其建设,包括信息通道、辅助系统和激励机制、及其形式和作用,建议根据社会经济发展的变化,不断完善技术转移要素建设。     

Key website factors in e-business strategy

The design of a quality website, as part of e-business strategy, has become a key element for success in the online market. This article analyzes the main factors that must be taken into account when designing a commercial website, concentrating on the Aceros de Hispania company and its business model. We have studied the features which determine website quality: accessibility, speed, navigability, content, and we have calculated the Web Assessment Index (WAI) proposed by Miranda and Bañegil [Miranda, F. J., & Bañegil, T. M. (2004). Quantitative evaluation of commercial websites: An empirical study of Spanish firms. International Journal of Information Management, 24(4), 313–328]. The results obtained provide several lessons which should be borne in mind when designing a commercial e-strategy. Firstly, it can be observed that Internet popularity and search engine positioning facilitate entry to practically inaccessible markets. Secondly, the navigability makes users feel comfortable and secure when browsing it, which increases the probability of a transaction being completed. Finally, the information provided on the website must be accurate, informative, updated and relevant to customers’ requirements. Like Aceros de Hispania, any company, thanks to the Internet, will be able to overcome the barriers which would impede its successful worldwide development in the offline market.     

人力资本的激励因素研究

本文通过对人力资本的分析,围绕职业经理人和技术创新者的需求特征,对人力资本的激励因素进行了研究,建立了全方位的激励模型,形成了人力资本激励因素指标体系。     

影响技术并购绩效的关键因素研究

 面对激烈的竞争、快速的技术更新,技术并购已经成为企业提升能力的一种重要方式。那么,技术并购到底有什么作用呢？究竟是什么因素影响企业技术并购的绩效呢？为什么技术并购行为不断增多,失败率却居高不下呢？在这三问题的指引下,基于文献综述,总结了技术并购的重要性,提出了企业技术并购绩效的影响因素之理论框架和研究命题,并为企业成功进行技术并购提出启示性建议。     

企业间信任的影响因素模型及实证研究/FONT

    摘要：企业间信任对促进企业间合作有着重要作用,本文从企业层面上探讨影响企业间信任的关键因素。论文通过文献阅读和回顾,整理了影响企业间信任的关键因素,并对这些因素进行了元分析,在元分析的基础上选取分析模型,并运用结构方程模型进行了验证。本文的研究对促进我国企业间建立信任关系有着重要的意义。       

专利维持时间影响因素研究

研究专利维持时间的影响因素对提高专利制度的运行绩效非常重要。技术领域和专利族等是影响专利维持时间的技术性因素;专利维持年费制度、保护范围、创造性标准和专利侵权的认定方式等是影响专利维持时间的制度性因素;专利管理制度和专利战略等是影响专利维持时间的创新主体因素。     

技术联盟知识转移影响因素的实证分析

摘要：本文针对技术联盟企业间知识转移的行为,深入分析了影响知识转移因素,构建了一个包含多个影响因素的模型,据此提出了相应假设,通过实地访谈和问卷调查,运用结构方程模型对国内251家企业的问卷数据进行分析。结果显示：知识的隐性、接收方学习动机、联盟伙伴间的知识差距、关系距离都能对联盟伙伴间的知识转移产生显著影响;相对于契约式联盟,股权式联盟更有利于知识转移效率的提高。     

Theory-based model of factors affecting information overload

As the volume of available information increases, individuals and organisations become overwhelmed by the plethora of information. This can reduce productivity and performance, hinder learning and innovation, affect decision making and well-being and cost organisations large amounts of money. This paper develops a new theory-based model of factors affecting information overload and provides a formula for calculating the extent of overload, potentially of use as a diagnostic tool supporting individual or organisational development.     

审计风险及影响因素的分析

针对审计工作的特点,论述了审计风险、审计职业风险及相关的错误拒绝风险与错误接受风险可能给审计活动带来的负面影响,分析了影响审计风险评估的诸多因素。     

影响技术创新活动的要素相关性研究

大多数学者通过分析技术创新投入与产出来表述技术创新的作用。区别于以往把专利要素作为投入指标的研究,把专利分为申请与授权,同时分属投入与产出要素,并以此为基础研究各要素间相互关系。研究发现,R&D、专利与技术转让等技术创新要素不能全部作为内生变量使用。运用卡尔曼滤波的方法可以找到一种度量单一技术创新水平的指标,进而描述中国在经济发展过程中技术创新的演进路程,并证明目前中国的技术创新活动已经遇到了瓶颈。     

他们的行为动机及其影响因素——基于辽宁省Z村两位农村民间组织青年负责人的个案研究

农村民间组织改变农村社会格局的一股新生且非常重要的力量,日益受到学术界的重视,该文以两位农村民间组织的组织者为个案,通过助人、成就、探索、交往四个维度研究他们的行为动机,并详细介绍了影响他们行为动机产生的正向因素(如自身需要、朋友和政府的支持)和负向因素(如自身能力的限制、家庭的不支持以及村民的不信任等)。     

论类比三要素的选择

汤建民提出了类比的三要素,类比源、类比泉和类比知识单元,并对类比源和类比知识单元的选择作了初步的研究。本文则在汤的研究基础上深入一步,并对选择类比泉的类比进行了系统的研究,尤其是把数学知识作为类比源的类比。在笔者看来,类比源、类比泉和类比知识单元的选择事关所类比对象的认识,决定类比成果的大小和意义。因此,研究如何选择类比三要素关系到类比的成功与否,其意义绝不亚于三个概念本身的提出。     

中小企业与科研机构产学研合作的制约因素研究

针对中国中小企业产学研合作的现状,分析了影响中小企业与科研机构产学研合作的制约因素,采用定性研究,结合发达国家促进中小企业参与产学研合作的相关做法,提出了我国中小企业参与产学研活动的相关政策建议.     

知识转移绩效影响因素分析

采用基于梯形直觉模糊数改进的DEMATEL方法对知识转移绩效的影响因素进行了分析,主要发现：（1）高关联强度、知识源的转移能力和转移动机是知识转移绩效的中心重要影响因素;（2）知识本身的因果模糊性、复杂性、内隐性等特征因素,是决定知识转移绩效的主要原因因素;（3）对影响度较高和中心度较高的影响因素进行管理和优化,是提升组织知识转移绩效的关键所在。本研究结论表明,对知识转移绩效影响因素的研究虽然趋于成熟,但仍需在各因素间影响方式和影响机制上进行深入研究。