Retroactive inhibition in rat spatial memory

Two experiments were carried out in which rats first were given four forced choices on an eight-arm radial maze, then were given interpolated maze experiences, and finally were given a free choice retention test on the first maze. In Experiment 1, interpolated experiences consisted of forced choices made on one, two, or three other mazes, each placed in a different room. Retroactive inhibition (RI) was not found with one and two interpolated mazes but was found with three interpolated mazes. In Experiments 2a and 2b, an attempt was made to produce RI within a single context by using two mazes placed side by side or on top of one another and by using interpolated forced choices that were different, random, or the same with respect to forced choices onMaze 1. These conditions failed to yield any evidence of RI. In Experiment 2c, forced choices were followed by interpolated direct placements on the same maze on different, random, or the same maze arms, and retention tests revealed RI under these conditions. It was concluded that rats encode memories of specific places visited in space and that RI will arise only if (1) memory is greatly overloaded with interpolated information or (2) an interpolated visit is made to exactly that position in space to which an animal must travel in order to achieve a correct choice on the retention test.     

Exploring the limits of spatial memory in rats,using very large mazes

In Experiment 1, rats foraged for food in six successive phases with 8, 16, 24, 32, 40, and 48 arms attached in random locations to a large radial maze. The percentage of novel choices appeared to be determined more by spatial proximity than by number of arms. In Experiment 2, rats foraged for food in four successive phases with 8, 16, 24, and 48 arms attached to the maze in spread-out or tight configurations. Performance was poor in the tight configurations regardless of the number of arms. Performance was excellent in the 8-arm spread-out condition but declined as 16 and, then again, 24 arms were added. Thus, spatial separation, not number of locations, was the chief determinant of performance in the first two experiments. In Experiment 3, in successive phases, 8, 16, 24, 32, 40, 48, 16, and 8 food towers were set in a circle on the floor, with the spatial separation between adjacent towers held constant at 33 cm. The percentage of novel choices declined as 8 towers became 16 and did not change again with 24, 32, 40, or 48 towers in place but then increased again as 16 towers became 8. In Experiment 4, in successive phases, 8, 16, 24, and 32 food towers were set in a circle, with the spatial separation between adjacent towers held constant at 66 cm. The percentage of novel choices declined as 8 towers became 16 and again as 16 towers became 24 but did not decline further. These data were discussed in terms of the fundamental problems posed by variations in the number of food locations in the pursuit of the limit of spatial memory in rats.     

Effects of varying trial distribution,intra- and extramaze cues,and amount of reward on proactive interference in the radial maze

Rats are typically less accurate in their arm selections in the radial maze over successive trials in a session (Roberts & Dale, 1981). In the present study, rats’ choice accuracy declined when such trials were separated by 2-min (massed) but not by 2-h (spaced) intertriai intervals. Changing intramaze visual/tactile arm stimuli (Experiments 1 and 3) or extramaze landmark stimuli (Experiment 4) between trials weakened the massed-trials effect, but changing the number of food pellets per arm, either alone or in conjunction with changes in intramaze cues (Experiments 2 and 3), did not. The rats also tended to avoid the spatial locations of their last four choices on a previous trial during their first four choices on a current trial, and more so with massed than with spaced trials. These findings indicate that intertriai proactive interference (PI) occurred only with massed trials and was weakened by changing intra- and extramaze cues between such trials.     

Intratrial proactive interference in rats’ serial alternation performance in the radial maze

Rats acquired a serial alternation task in an eight-arm radial maze that was partitioned into four pairs of arms. Each pair was associated with a different distal stimulus. Rats were initially forced to the left or right arm in each pair (the study segment) before being exposed to both arms in each pair (the free-choice or test segment). Only the previously blocked arm of each pair remained baited. Following initial training, proactive interference (PI) was induced by presenting rats with a forced-choice (prestudy) segment containing arm positions opposite those in the subsequent study segment. Such trials generated poorer free-choice accuracy than did trials without a prestudy segment. Forcing rats to both arms in the pair in a prestudy segment produced only transient PI. A slight improvement in rats’ free-choice performance was obtained by forcing them to the same arm position, but only when the test segment was delayed by 30 min. Increasing the interval between the prestudy and study segments from 2 to 30 min eliminated PI, but only when free-choice testing was delayed by 2 min rather than by 30 min. These results suggest that intratrial PI in this preparation was primarily due to confusion about which arm position in each pair had been visited during the last forced-choice segment.     

Spatial pattern learning in the radial arm maze

Rats experienced a spatial pattern of baited and unbaited arms in an eight-arm radial maze. The spatial pattern remained constant over trials, but the spatial locations that were baited varied unpredictably. Although there was no evidence of control by the spatial pattern during free choice training trials, the rats’ ability to locate baited arms in forced choice test trials was superior to that of animals in a control condition for which maze arms were not baited in a consistent spatial pattern. This is consistent with the results of experiments showing that spatial choices by rats in a pole box maze are controlled by abstract spatial patterns.     

Retroactive interference in rat radial maze performance: The role of point of delay interpolation and the similarity and amount of interpolated material

The conditions necessary for producing retroactive interference (RI) were examined in a 12-arm radial maze. Rats were first given either three or nine forced choices in a to-be-remembered maze. During a 2-h delay, they received one or two trials in a second 12-arm maze, located either in a different room or the same room as the to-be-remembered maze. During the postdelay memory test, RI from the interference trials was produced only when nine choices had been made in the to-be-remembered maze and two interference trials had been conducted during the delay interval. RI was not found when only three forced choices had to be retained or after a single interference trial. The similarity between the interpolated and to-be-remembered mazes had no effect on choice accuracy. It was concluded that two conditions are required for the production of RI in the radial maze. First, a “large amount” of information should be resident in working memory. Second, a substantial number of interpolated trials or choices must be made during the delay.     

The sensory basis of spatial memory in the rat

Rats were given three stages of training on an eight-arm, elevated radial maze with food reward at the end of each arm. In Stage 1, rats were allowed to choose freely among the arms from the beginning of a trial. In Stage 2, three initial forced choices were followed by a series of free choices. In Stage 3, the central platform of the maze was rotated with the rat on it between the initial forced choices and the free choices. Following testing on these three stages, the animals were divided into four groups and deprived of selected senses. One group was made blind, a second anosmic, a third blind and anosmic, and a fourth was left normal. The same three stages of testing that had been conducted preoperatively then were run again post-operatively. Throughout these tests, the possible use of auditory cues was tested by presenting white noise on alternate trials. Finally, two further tests were carried out, the multiple rotations test and the removal-replacement test. The results indicated that visual cues, but not olfactory or auditory cues, played a critical role in the rat’s ability to avoid previously entered alleys. There was evidence also that rats used internal cues from kinesthetic and/or vestibular receptors when visual cues were absent.     

Effects of runway shift and stay rules on rats’ serial pattern learning in the T-maze

Rats received three-trial series on a T-maze consisting of extended visually distinct left-black and right-striped side runways. During the first phase of training, when allowed to select baited runways within these series, they predominantly alternated their choices. During the second phase, rats received forced-choice serial pattern training of series consisting of two rewarded (R) trials and one nonrewarded (N) trial in two fixed orders, RRN and RNR. In Experiment 1, the rats in the runway shift rule group always received the second R trial when forced down a runway opposite that on the preceding trial in the series and the N trial when forced down the same runway. The rats in the runway stay rule group always received the second R trial when forced down the same runway and the N trial when forced down the opposite runway. In Experiment 2, each rat was conditionally trained with both runway outcome rules as determined by the central alley lighting and the type of food in the side alleys. The rats took longer to reduce their running speed on the N trial within each sequence under the runway stay rule than under the runway shift rule. They also took longer to acquire serial pattern responding for the RNR than for the RRN series only under the runway stay rule condition. When subsequently reexposed to series of free-choice trials on the final phase, rats maintained spontaneous alternating choice patterns under the runway shift rule conditions but either seldom alternated their choices (Experiment 1) or greatly reduced choice alternations (Experiment 2) under the runway stay rule condition. We discussed these effects in terms of rats’ natural foraging strategies and as a factor that interacts with other within- and between-series variables that affect serial pattern behavior.     

Rat spatial memory: Resistance to retroactive interference at long retention intervals

An attempt was made to disrupt memory for spatial information by interpolating a task of high similarity to the to-be-remembered task during a long retention interval. Rats were trained in an 8-arm maze in which choosing each arm without repetition was the optional strategy. A 4-h delay was imposed between the 4th and 5th choices. At various times during the retention interval, the rats ran a second identical maze located in another room. No evidence of retroactive interference was observed. In the second experiment, the rat was required to remember the interpolated spatial task during the retention test. This was accomplished by allowing the rat to make four choices in the first maze and then, after a variable period of time, four choices in the second maze. Four hours after exposure to each maze, retention was tested. Choice accuracy on the retention tests was high and equivalent on both mazes. Requiring the rat to remember which arms it had visited in a second maze did not impair memory for the first maze. These results demonstrate that rats can segregate spatial memories established in different contexts with considerable proficiency.     

Evidence for a shift in the choice criterion of rats in a 12-arm radial maze

Rats were trained in a standard 12-arm radial maze task. Following training, each trial consisted of a sequence of 2, 4, 6, 8, or 10 choices, followed by a 15-min delay, which then was followed by a choice between a single arm and a response manipulandum mounted in the center of the maze. An arm visit was reinforced if the arm had not been visited prior to the delay, whereas a manipulandum response was reinforced if the arm had been visited. It was found that rats are relatively more likely to reject arms by responding to the manipulandum following a delay occurring late in the choice sequence. This indicates that the choice criterion used by rats in the radial maze becomes more strict as the choice sequence progresses. Such a process provides an alternative explanation for some of the data recently reported by Cook, Brown, and Riley (1985).     

Development of excitatory backward associations during the establishment of forward associations in a delayed conditional discrimination by pigeons

The development of excitatory backward associations in pigeons was demonstrated in three experiments involving conditional discriminations with differential outcomes. In Phase 1 of all three experiments, correct comparison choices following one sample were followed by food, whereas correct comparison choices following the other sample were followed by presentation of an empty feeder. In Phase 2, the food and no-food events that served as outcomes in Phase 1 replaced the samples. When the associations tested in Phase 2 were consistent with the comparison-outcome associations developed in Phase 1, transfer performance was significantly better than when the Phase 2 associations were inconsistent with the Phase 1 associations. In Experiment 1, an identity matching-to-sample task was used with red and green samples and red and green comparisons. In Experiment 2, a symbolic matching task was used with shape samples and hue comparisons, and it was shown that the backward associations formed were between the trial outcome (food or no food) and the correct comparison. In Experiment 3, it was determined that the transfer effects observed in these experiments did not depend on either the similarity of behavior directed toward the samples in the training and test phases, or the similarity of food and no-foodexpectancies generated by the samples in Phase 1 to food and no-foodevents presented as samples in Phase 2.     

In the dark: Spatial choice when access to spatial cues is restricted

The cognitive mechanisms involved in spatial choice when access to visual cues is restricted were examined in three experiments using male rats. A specially constructed radial-arm maze was used, in which extramaze visual cues could not be perceived from the central arena, but could be perceived from the maze arms. Choices were very accurate when the maze was not rotated during each trial, but inaccurate when the maze was rotated. This suggests that intramaze cues were involved in the control of choices. However, the data clearly showed that choices were not simply controlled by intramaze cues. Rather, control by intramaze cues interacted in a more complex manner with representations of the spatial locations of goals. Such spatial representations were involved in the control of choice despite the absence of visual spatial cues at the time choices were made.     

Proactive interference, recency, and associative strength: Comparisons of black-capped chickadees and dark-eyed juncos

Black-capped chickadees (Parus atricapillus) and dark-eyed juncos (Junco hyemalis) were required to match to the last item from a series of up to three stimuli differing in both location and color. When rewarded for pecking the target stimulus during the study phase of each series, black-capped chickadees demonstrated proactive interference (PI) from stimuli presented prior to the target, whereas juncos did not. When they made an error, chickadees were more likely than were juncos to choose a distractor from the study series rather than a novel stimulus. When reward was no longer associated with presentation of the final target sample in a series, juncos also suffered PI. These results indicate that chickadees and juncos differ in the degree to which the recency of stimuli and the associative strength of stimuli control correct matching.     

Overconfidence produces underachievement: Inaccurate self evaluations undermine students’ learning and retention

The function of accurately monitoring one’s own learning is to support effective control of study that enhances learning. Although this link between monitoring accuracy and learning is intuitively plausible and is assumed by general theories of self-regulated learning, it has not received a great deal of empirical scrutiny and no study to date has examined the link between monitoring accuracy and longer-term retention. Across two studies, college students paced their study of key-term definitions (e.g., “Proactive interference: Information already stored in memory interferes with the learning of new information”). After all definitions were studied, participants completed practice cued recall tests (e.g., “What is proactive interference?”) in which they attempted to type the correct definition for each term. After each test trial, participants judged how much of their response was correct. These study-test-judgment trials continued until a definition was judged as correct three times. A final cued recall test occurred two days later. In Study 1, judgment accuracy was manipulated experimentally, and in Study 2, individual differences in accuracy were examined. In both studies, greater accuracy was associated with higher levels of retention, and this link could not be explained by differential feedback, effort during study, or trials to criterion. Results indicate that many students could benefit from interventions aimed at improving their skill at judging their learning.     

干扰负载对注意缺陷多动障碍儿童视觉工作记忆的影响

为考察编码和提取阶段的干扰负载对注意缺陷多动障碍(ADHD)儿童视觉工作记忆的影响。本研究采用纸笔测验,分别要求被试对编码和提取阶段的材料进行操作。结果发现,编码阶段,干扰负载对两组被试的影响没有显著差异;提取阶段,干扰负载对ADHD组被试的影响显著大于普通组被试。相对于普通组儿童而言,ADHD儿童的视觉工作记忆更易受到干扰负载的影响,这种影响体现在提取阶段。     

Rats remember not wisely but too well

Rats were trained in a three-alternative spatial delayed matching-to-sample task in a starburst maze. Samples consisted of rewarded forced choices of one arm, and retention was indicated by rats’ returning to that arm after a 90-sec delay. If a rat made an error on its first choice, it was returned to the start compartment and allowed a second choice. Unlike in previous experiments with this task, all three arms were available during the animals’ second choices. The rats tended to perseverate in their second choices by returning to the arm that they had erroneously visited on their first choice. In Experiment 1, the accuracy of second choices following first-choice errors was below chance during the first block of sessions, when a 90-sec delay intervened between the first choice and the second choice, and at chance during the second block of sessions, when a short (5–6 see) delay intervened between first and second choices. In Experiment 2, long-delay and short-delay sessions were randomly presented to naive subjects. Similar results were obtained. In both experiments, the tendency to repeat the erroneous first choice was greater when long delays separated the two choices than when short delays were used. The results suggest that rats make their first-choice errors because they erroneously encode or remember the location of the sample and that they base their second choices on the same erroneous-memory. The increase in perseveration at long delays implies some kind of rehearsal-like mechanism that slows forgetting of the memory controlling the first choice.     

The role of question type and reading ability in reading comprehension

Performance on a standardized reading comprehension test reflects the number of correct answers readers select from a list of alternate choices, but fails to provide information about how readers cope with the various cognitive demands of the task. The aim of this study was to determine whether three groups of readers: normally achieving (NA), poor comprehenders (CD), with no decoding disability, and reading disabled (RD), poor comprehenders with poor decoding skills, differed in their ability to cope with reading comprehension task demands. Three task variables reflected in the question-answer relations that appear on standardized reading comprehension tests were identified.Passage Independent (PI) question can be answered with reasonable accuracy based on the reader's prior knowledge of the passage content.Inference (INFER) questions required the reader to generate an inference at the local or global test level.Locating (LOCAT) questions require the reader to match the correct answer choice to a detail explicitly stated in the text either verbatim or in paraphrase form. The relations among reader characteristics, cognitive task factors and reading comprehension test scores were analyzed using a structural relations equation with LISREL. It was found that the three reading groups differed with respect to the underlying relationship between their performance on specific question-answer types and their standardized reading comprehension score. For the NA group, a high score on PI was likely to be accompanied by a low score on INFER, whereas in the CD and RD groups, PI and INFER are positively related. The finding of a negative relationship between background knowledge and inference task factors for normally achieving readers suggests that even normal readers may have comprehension difficulties that go undetected on the basis of a standardized scores. This study indicates that current comprehension assessments may not be adequate for assessing specific reading difficulties and that more precise diagnostic tools are needed.     

The Robustness of Infant Haptic Memory: Testing Its Capacity to Withstand Delay and Haptic Interference

The robustness of infant haptic memory was assessed in terms of its capacity to withstand either a brief delay or potential retroactive "interference" from other haptic input. 48 infants (mean age 8 months) were familiarized haptically to a small cube or sphere with smooth or rough surface texture and subsequently tested for recognition of the shape and texture of this stimulus in terms of the relative level of haptic response to 3 test stimuli, comprising the familiar stimulus, a new-shape stimulus, and a new-texture stimulus. The test stimuli were presented ( a ) immediately, ( b ) after a 5-min delay, or ( c ) after a second familiarization or "interference" phase involving another haptic stimulus different in shape and texture to the first. The infants demonstrated recognition of shape and texture in the No Delay condition, of shape and (marginally) of texture in the Delay condition, but only of texture in the Interference condition. The greater susceptibility of shape to interference was considered in terms of the degree of similarity among the shapes employed in the study.