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1.
Alfredo Ardila 《Reading and writing》1989,1(3):195-200
Summary The case of a left-handed female patient is described who presented serious problems in learning how to write during childhood, particularly in relation to directionality and letter sequence. The patient then learned to write correctly with her left hand, but practiced and maintained her ability to write backwards (from the last letter to the first). Implications of the case are discussed.Send Correspondence to Dr. Alfredo Ardila, Miami Institute of Psychology of the Caribbean Center for Advanced Studies, 8180 NW 36 Street, Second floor, Miami, Florida 33166-6612. 相似文献
2.
The literature on Cultural Economics provides us with some examples for the measurement of technical efficiency. However, there are few case studies dedicated to the analysis of allocative efficiency. The aim of this paper is to fill this gap by incorporating a methodology that analyses both technical and allocative efficiency. We use the Shephard’s distance function, particularly suitable when affronted with non-profit-making firms or institutions that are not interested in cost minimization. As an empirical application, we analyse the efficiency of Fundación Princesa de Asturias (PAF), a Spanish non-governmental organization devoted to promoting the cultural, scientific and humanistic values of universal heritage, the period of study being 1988–2012. Our findings suggest that PAF could have used 7% less inputs to achieve the same level of output. On the other hand, we have found allocative inefficiency. Concretely, the input for other expenditures appears to have been over-utilized in relation to both the inputs for labour and current assets, with labour in turn being over-utilized in relation to current assets. Moreover, our results indicate that both technical and allocative efficiency have clearly improved during the period analysed. In summary, our empirical application shows how distance function methodology can be successfully implemented to measure allocative efficiency in cultural firms and institutions. 相似文献
3.
The aims of this study were to examine the changes in plasma concentrations of inflammatory cytokines induced by training and competition in professional cyclists. We report the serum concentrations of interleukin-6 (IL-6), tumour necrosis factor alpha (TNF-a), tumour necrosis factor receptors I and II (TNFR-I and -II) in a prospective, randomized, double-blind trial involving the administration of AM3 (Inmunoferon), an oral booster immunomodulator, or placebo to 16 professional cyclists (n = 8 in each group) for 65 consecutive days. Serum was collected just before treatment began (baseline), at the end of pre-competition training, before the mountain stage of the competition (60 days), 4 h after finishing this stage (62 days), and 18 h after the fifth and last day of competition (65 days). To determine the normal levels of cytokines and soluble TNF receptors, individual samples from 14 moderately trained healthy controls were studied. After 60 days of training, the serum concentrations of IL-6 did not differ significantly from those at the beginning of the study for either group of cyclists (placebo and AM3). A significant rise was seen in IL-6 concentrations in both the AM3 and placebo groups at 62 days, 4 h after finishing the mountain stage. The increase was significantly greater in the placebo group than in the AM3 group. At 65 days of treatment, 18 h after the fifth and last day of competition, IL-6 concentrations were similar to those recorded at the end of the training, but were significantly higher in the placebo group than in the AM3 group. At the end of training, serum TNFR-I concentrations in both groups of cyclists were significantly lower than at baseline. The concentrations of serum TNFR-I and -II both 4 h after finishing the mountain stage and 18 h after the fifth and last day of competition were significantly higher than those recorded after training in both groups. Professional cycling competition is associated with increases in serum IL-6 and TNFR-I and -II concentrations. Inmunoferon treatment reduced significantly the concentrations of IL-6 but not those of TNFR-I and -II. 相似文献
4.
Silvia Izquierdo álvarez Eva Barrio Ollero Francisco Miguel Llinares Sanjuan Fabiola Lorente Martínez María Teresa Calvo Martín 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2014,24(1):159-166
Introduction:
Additional nucleotide substitutions in the 3′-untranslated region of prothrombin gene could explain some thrombotic events and also adverse pregnancy outcomes. We describe the first case of a homozygous 20209C>T mutation as the cause of deep vein thrombosis in a Spanish patient.Case and methods:
The 56-year-old male patient with a partial tear of the Achilles tendon developed calf (tibial) deep vein thrombosis after immobilization and was treated with an anticoagulant. To determine if the deep vein thrombosis was of genetic origin, a peripheral blood DNA sample was analysed for the presence of the three most frequent mutations associated with thrombotic events: factor V Leiden (1691G>A), prothrombin (20210G>A) and methylene tetrahydrofolate reductase (677C>T). The presence or absence of the normal allele of prothrombin could not be determined using the PTH-FV-MTHFR StripAssay (Vienna Lab).Results:
Comprehensive analysis showed that the patient had a variant interfering with the polymerase chain reaction product, we sequenced the entire prothrombin gene and found that the patient had a homozygous C>T mutation at position 20209; this interfered with the polymerase chain reaction product, which needs a C at this position to be able to bind to the wild-type probe present in the test strip.Conclusion:
The homozygous 20209C>T mutation and the presence of the mutation 677C>T in heterozygosity explained the patient’s deep vein thrombosis because the combination of mutations would increase the risk of thrombosis. Suitable genetic counselling should be provided to the patient and first-degree relatives as it important to detect prothrombin gene variants that could increase risk for thrombotic events. 相似文献5.
Paz Surez‐Coalla Marta lvarez‐Caizo Fernando Cuetos 《Journal of Research in Reading》2016,39(3):292-311
In order to read fluently, children have to form orthographic representations. Despite numerous investigations, there is no clear answer to the question of the number of times they need to read a word to form an orthographic representation. We used length effect on reading times as a measure, because there are large differences between long and short words for unknown words, differences that disappear when reading frequent words. Two lists of new words (half short and half long) were presented to 102 second‐grade to sixth‐grade Spanish children, to be read aloud six times. One of the lists was presented as part of a story and the other in isolation. Comparison of the length effect at the first and sixth exposure showed large differences between short and long words in the first presentation and small differences at the sixth presentation, indicating that Spanish children develop representations of words after just a few repetitions. 相似文献
6.
Teaching students how to conduct bibliographic searches in health sciences’ databases is essential training. One of the challenges librarians face is how to motivate students during classroom learning. In this article, two hospital libraries, in Spain, used Escape rooms as a method of bringing creativity, teamwork, communication and critical thinking into bibliographic search instruction. Escape rooms are a series of puzzles that must be solved to exit the game. This article explores the methods used for integrating escape rooms into training programmes and evaluates the results. Escape Rooms are a useful tool that can be integrated into residents’ training to support their instruction on bibliographic searches. This kind of learning stablishes competences like logical thinking and deductive approaching. These aspects aid participants to make their own decision and to develop social and intellectual skills. 相似文献
7.
Isabel Gallego-Álvarez Luis Rodríguez-Domínguez Isabel-María García-Sánchez 《Government Information Quarterly》2010
The implementation of E-government aims at simplifying and improving the transactions between public administrations and their users or customers. The objective of this study is to analyze whether the factors behind the level of development of E-government among municipalities of a specific country are common to the improvement of digital administration in the largest municipalities from 81 countries worldwide. While previous studies provide evidence that municipalities from the same country, mainly those governed by left-wing parties, focus on differentiating themselves in the content of their Web sites, our findings emphasize that internationally, in the most important municipalities worldwide, all the political parties attempt to promote the development of a dynamic and participatory E-government. 相似文献
8.
We review empirical research on English language learners (ELLs) who struggle with reading and who may have learning disabilities (LD). We sought to determine research indicators that can help us better differentiate between ELLs who struggle to acquire literacy because of their limited proficiency in English and ELLs who have actual LD. We conclude that more research is warranted to further elucidate the strengths and learning needs of subgroups of underachieving ELLs, to help us determine who should qualify for special education, and to clarify why some ELLs who do not have LD still struggle with language and literacy acquisition. Future research should account for the complexities involved in becoming literate in another language and focus more on cultural and contextual factors that affect student achievement. 相似文献
9.
Alberto Fílter Jesús Olivares Alfredo Santalla Fabio Y. Nakamura Irineu Loturco Bernardo Requena 《Journal of sports sciences》2020,38(11-12):1320-1325
ABSTRACT The speed performance is involved not only in linear sprints, but also in a wide spectrum of multi-directional movements, such as curve sprinting. Curved sprint can be defined as sprint with gradual and continuous change of direction (COD). Although ~85% of the actions performed at maximum velocity in a professional soccer league are curvilinear sprints, there is not any specific test to assess this ability. This study aimed to analyse the reliability of a new curve sprint test, and compare its results with those obtained by soccer players in linear sprint. Forty experienced soccer players performed 3 attempts of curve sprint (using the penalty arc) to right and left side (17 m), and 3 linear sprints (17 m) in two different days. The ICCs (inter-session reliability) were 0.93 for sprint curve right side (CSRS) and 0.89 for sprint curve left side (CSLS), considered “acceptable”. The CVs (intra-session reliability) were 0.87% in CSRS and 1.15% in CSLS. The coefficient of determination (R2) between linear and curve sprinting was ~35%. The association between curve sides was “very large” (r = 0.878; p < 0.01). In summary, we showed that “curve sprint test” is highly reliable, and that curvilinear and linear sprints are different and independent actions. 相似文献
10.
José BARRIGA 《浙江大学学报(A卷英文版)》2008,9(10):1369-1372
This paper describes a vision-based system for blind spot detection (BSD) in intelligent vehicle applications. A camera is mounted in the lateral mirror of a car with the intention of visually detecting cars that are located in the so-called blind spot and cannot be perceived by the vehicle driver. The detection of cars in the blind spot is carried out using computer vision techniques, based on optical flow and a double-stage data clustering technique for robust vehicle detection. 相似文献