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Ferenc Torma Zoltan Gombos Marcell Fridvalszki Gergely Langmar Zsofia Tarcza Bela Merkely Hisashi Naito Noriko Ichinoseki-Sekine Masaki Takeda Zsolt Murlasits Peter Osvath Zsolt Radak 《运动与健康科学(英文)》2021,10(4):470-477
BackgroudBlood flow restriction (BFR) with low-intensity resistance training has been shown to result in hypertrophy of skeletal muscle. In this study, we tested the hypothesis that BFR during the rest periods between acute, high-intensity resistance exercise sessions (70% of 1 repetition maximum, 7 sets with 10 repetitions) enhances the effects of the resistance training.MethodsA total of 7 healthy young men performed squats, and between sets BFR was carried out on one leg while the other leg served as a control. Because BFR was applied during rest periods, even severe occlusion pressure (approximately 230 mmHg), which almost completely blocked blood flow, was well-tolerated by the participants. Five muscle-specific microRNAs were measured from the biopsy samples, which were taken 2 h after the acute training.ResultsDoppler data showed that the pattern of blood flow recovery changed significantly between the first and last BFR. microRNA-206 levels significantly decreased in the BFR leg compared to the control. The mRNA levels of RAC-β serine/threonine-protein kinase v22, nuclear respiratory factor 1, vascular endothelial growth factor, lupus Ku autoantigen protein p70 genes (p < 0.05), and paired box 7 (p < 0.01) increased in the BFR leg. The protein levels of paired box 7, nuclear respiratory factor 1, and peroxisome proliferator-activated receptor γ coactivator 1α did not differ between the BFR leg and the control leg.ConclusionBFR, during the rest periods of high-load resistance training, could lead to mRNA elevation of those proteins that regulate angiogenesis, mitochondrial biogenesis, and muscle hypertrophy and repair. However, BFR also can cause DNA damage, judging from the increase in mRNA levels of lupus Ku autoantigen protein p70. 相似文献
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Jackie Dearden Anne Emerson Tom Lewis Rebecca Papp 《British Journal of Special Education》2017,44(1):8-25
This longitudinal case study of a 10‐year‐old girl with autism and severe communication impairment measures the impact of the MORE (Means, Opportunities, Reasons and Expectations) approach to enhancing engagement and communication. Through detailed observation of video data over a period of 28 months, engagement behaviours including interaction with adults and following adult directions increased, while resistant behaviours such as kicking, hitting and pushing adults away decreased. Fluctuation between different ‘states’ demonstrated that the frequency and duration of engagement was influenced by the MORE approach and an emphasis on developing intrinsic motivation. In order to enable further efficacy research, core features of the intervention and the changes in engagement over time are described. 相似文献
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Ferenc Süle 《High Ability Studies》1991,1(2):162-164
The way of life of top athletes imposes a burden exceeding the average not only on the biological but also on the psychological level. Apart from somatic problems, this may result in psychological disturbances which necessitate psychotherapeutic treatment. To achieve peak performance, both somatically and mentally superior levels of health and strength are needed. On the basis of this conviction, 50 first class young sportsmen were prepared over a period of 6–8 months, using procedures such as autogenic training, imaginative psychotherapy, imaginative mental training and training on altered states of consciousness.‐Results indicated that these athletes suffered fewer injuries, were less often absentfrom training, obtainedfewer competition results below their training performance and showed more frequent improvement of performance. These findings show that psychotherapeutic work with top athletes can be a useful part of their preparation. 相似文献
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Alisa N. Almas Leanna J. Papp Margaret R. Woodbury Charles A. Nelson Charles H. Zeanah Nathan A. Fox 《Child development》2020,91(1):96-109
This study examined disruptions in caregiving, as well as the association of these disruptions, with cognitive, behavioral, and social outcomes at age 12 in a sample of 136 Romanian children who were abandoned to institutions as infants and who experienced a range of subsequent types of care. Children were found to experience significantly more caregiving disruptions (CGD) earlier in life than later in childhood. More frequent CGD predicted increases in externalizing and internalizing behavior problems at age 12. Results are discussed in terms of the association between CGD and the long-term development of children who have experienced institutional rearing. 相似文献
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Mothers' and fathers' reports of marital conflicts in the home were obtained (n = 1,638 and 1,281 conflicts, respectively), including conflicts in front of the children (n = 580 and 377, respectively). Participants were 116 families with children 8 to 16 years old (M = 10.82 years, SD = 2.17; 58 boys, 58 girls). Children's emotional responses indicated distinctions between distressing conflict tactics (i.e., threat, personal insult, verbal hostility, defensiveness, nonverbal hostility, marital withdrawal, physical distress) and those that increased their emotional security (i.e., calm discussion, support, affection). Analyses based on cross-reporter informants of parental conflict and child responses strengthened confidence in the findings. Conflict tactics were related to marital functioning, and children's emotional reactions during marital conflicts were associated with their adjustment. 相似文献
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Donna A. Demac Leland L. Johnson Anne G. Keatley John R. McIntyre Daniel S. Papp Albert Teich 《Communication Booknotes Quarterly》2013,44(3-4):38-39
TRACING NEW ORBITS: COOPERATION AND COMPETITION IN GLOBAL SATELLITE DEVELOPMENT edited by Donna A. Demac (New York: Columbia University Press, 1986—$35.00) ISSUES IN INTERNATIONAL TELECOMMUNICATIONS: GOVERNMENT REGULATION OF COMSAT by Leland L. Johnson (Santa Monica, CA: Rand Corp., 1987—price not given, paper) TECHNOLOGICAL FRONTIERS AND FOREIGN RELATIONS edited by Anne G. Keatley (1985—$19.95, paper, 306 pp.) THE COMPETITIVE STATUS OF THE U.S. ELECTRONICS INDUSTRY: A STUDY OF THE INFLUENCES OF TECHNOLOGY IN DETERMINING INTERNATIONAL INDUSTRIAL COMPETITIVE ADVANTAGE (1984—$10.95, 126 pp.) THE POLITICAL ECONOMY OF INTERNATIONAL TECHNOLOGY TRANSFER edited by John R. McIntyre and Daniel S. Papp (Westport, CT: Quorum Books/Greenwood Press, 1986—$45.00) SCIENCE AND TECHNOLOGY IN THE USA by Albert Teich and Jill Pace (Detroit: Gale Research, 1986—$95) 相似文献
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Nóra Imre Réka Balogh Edina Papp Ildikó Kovács Szilvia Heim Kázmér Karádi 《Educational gerontology》2013,39(8):495-505
General practitioners (GPs) play a pivotal role in dementia recognition, yet research suggests that dementia often remains undetected in primary care. Lack of knowledge might be a major contributing factor to low recognition rates. Our objective was to address a gap in the scientific literature by exploring GPs’ knowledge on dementia and mild cognitive impairment (MCI) for the first time in Hungary by conducting a cross-sectional, questionnaire study among practicing GPs. Recruitment of the participants (n = 402) took place at mandatory postgraduate training courses and at national GP-conferences; the applied questionnaire was self-administered and contained both open-ended and fixed-response questions.Results showed that GPs highlighted vascular and metabolic factors (38.3% of the answer items) and unhealthy lifestyle (29.1% of the answer items) as dementia risk factors. They perceived vascular dementia as the most common dementia form, followed by Alzheimer’s disease. Almost half of the respondents (44.9%) were not familiar with MCI. Most GPs identified memory problems (98.4%) and personality change (83.2%) as the leading symptoms of dementia.In summary, GPs demonstrated adequate knowledge on areas more relevant to their practices and scope of duties (risk and preventive factors, main types and symptoms of dementia); however, uncertainties were uncovered regarding epidemiology, MCI, and pharmacological therapy. As only one-fifth (19.4%) of the GPs could participate recently in dementia-focused trainings, continued education might be beneficial to improve dementia detection rates in primary care. 相似文献