Association between SNP rs1800875, serum chymase and immunoglobulin E levels in patients with coronary heart disease

Objective  

The gene for mast cell chymase (CMA1) is an ideal candidate for investigating the genetic predisposition to coronary heart disease (CHD), as activated mast cells have been found to be present in a greater proportion in the shoulder region of atheroma than in normal coronary intimae. Previous studies have indicated that CMA1 promoter polymorphism rs1800875 may be involved in regulating immunoglobulin E (IgE) levels in patients with eczema, and it is associated with the progression of immunoglobulin A nephropathy.     

Genotypic differences in callus induction and plant regeneration from mature embryos of barley (Hordeum vulgare L.)

An efficient induction system and regeneration protocol based on mature barley embryos were developed. Embryos isolated from mature seeds, dehusked by hand and inoculated with longitudinally bisected sections, showed low contamination and high primary callus-forming capability. The influences of nine culture media on primary callus induction and germination from the mature embryos of barley cultivars Golden Promise and Zaoshu 3 were analyzed. The results showed that the two cultivars had much higher values of primary callus induction in the B16M6D medium as compared to the other eight medium formulations, with a frequency of 74.3% and 78.4% for Golden Promise and Zaoshu 3, respectively. Furthermore, Zaoshu 3 demonstrated particularly high stability in callus induction over the different media, indicating its potential utilization in callus induction and regeneration for its good agronomic traits and wide adaption. There were significant differences amongst 11 barley genotypes in terms of primary callus induction in the optimum medium, with percentages of callus induction and germination response ranging from 17.9% to 78.4% and 2.8% to 47.4%, respectively. Green plantlets of Dong 17, Golden Promise, and Zaoshu 3 were successfully developed from primary calli through embryogenesis, with green plant differentiation frequencies ranging from 9.7% to 21.0% across genotypes.     

边界与桥梁:博物馆与全球文化和谐

数十年来,在政治、经济和技术变化支撑下,全球沟通联络越来越多,很多国家重新开始加强边界和国家认同,以便应对真实的和网络的恐怖主义和大规模移民,这些国家变得愈发保守和多疑。博物馆作为建立边界和认同的机构,对预防这种倾向非常关键,通过文化活动和国际展览维持国家之间的良好关系,建立对话平台和沟通的桥梁,促进共同理解,致力于“全球文化和谐”,从不同角度思考文化对于我们理解世界的作用。它涉及最终扫除隐藏于学院学科和艺术、现代化和博物馆等概念中的西方文化帝国主义最后残余。全球性未来关乎对文化与文化产品的本土化理解,关乎对全球文化多元性的更新性欣赏。     

Design of CMOS Mixer with Complementary Transconductance

<正>A current bleeding CMOS mixer with complementary transconductance stage is presented in this paper.The conversion gain of the mixer is increased and the flick noise of the mixer is reduced by inserting the PMOS to form current bleeding circuit in Gilbert mixer.The circuit is designed through SMIC 0.18um CMOS process,the LO frequency is 1.571GHz,RF frequency is 1.575GHz,simulation results show the conversion gain of the mixer is 18.5 dB,SSB NF is about 9.59dB,and third-order input intercept point(IIP3) is-4.6dBm.The mixer consumes 7.8 mA at 1.8 V power supply and the size of the whole layout is 0.73mm×0.68 mm.     

Cathodic electrolyte engineering toward durable Zn–Mn aqueous batteries

<正>Zn–Mn aqueous batteries (ZMABs)present potential for grid-scale energy storage with the benefits of low cost,high safety and eco-friendliness [1].Since 1866 (Leclanchéwet cell), we have witnessed the prosperity of ZMABs in the primary battery market and an increasing interest in rechargeable ZMABs.     

Rhesus monkeys exhibiting spontaneous ritualistic behaviors resembling obsessive-compulsive disorder

Obsessive-compulsive disorder(OCD) is a chronic and debilitating psychiatric disorder that affects ～2%–3% of the population globally. Studying spontaneous OCD-like behaviors in non-human primates may improve our understanding of the disorder. In large rhesus monkey colonies, we found 10 monkeys spontaneously exhibiting persistent sequential motor behaviors(SMBs) in individual-specific sequences that were repetitive, time-consuming and stable over prolonged periods. Genetic analysis revealed seve...     

＂City of Museums＂： a New Brand for Qujiang,Xi＇an

Modern museums are striving to keep pace with the rapidly evolving modern art and the changing needs of audience. Accordingly, the concept of museum has developed and trans- formed. Imagine the future of Xi＇an as a city of museums. It will be a city immersed in a profound artistic atmo- sphere, embracing broader space for exchanges, exhibiting higher educa- tional value, thus truly demonstrating the cultural background required for an international city. This is exactly what we have been hoping for a city＇s cultural inheritance.     

试论高师数学教育研究的原则与选题

提出高师数学教育研究的３条原则与７个方面的选题．     

Accuracy of a combined score of zygote and embryo morphology for selecting the best embryos for IVF

Objective:To evaluate the accuracy of a scoring system combining zygote and embryo morphology in predicting the outcome of in vitro fertilization(IVF)treatment.Methods:In a study group,117 consecutive IVF or intracytoplasmic sperm injection(ICSI) cycles with embryo transfer were carried out and 312 embryos were scored Using a combmed scoring system(CSS)of zygote and embryo morphology before transplantation.In a control group,a total of 420 IVF or ICSI cycles were carried out and 1176 embryos were scored using a cumulative embryo score(CES).The effects of the combined scoring system on the embryo implantation rate and pregnancy rate per cycle were analyzed.Results:Using the combined scoring system,the embryo implantation rate(27.6%)and the clinical pregnancy rate(48.7%)were significantly higher than those in the control group(20.8%and 38.6%,respectively).Also,the implantation rate of embryos scoring≥70 (38.5%:82 sacs/213 embryos)was significantly higher (P＜0.001)than that of embryos scoring＜70(4%:4 sacs/99 embryos).The pregnancy rate of patients with embryos scoring≥70 using the combined scoring system(66.7%)Was significantly higher(P＜0.001)than that of patients with embryos scoring≥20 using the cumulative embryo score(59.0%).Conclusion:The results suggest that selecting embryos with a high Score(≥70)using the combined scoring system could inerease the implantation rate and pregnancy rate,and that using a scoring system combining assessments of human zygotes and pre-implantation embryos might predict IVF outcomes more accurately than using a cumulafive embryo score.     

Anaerobic ammonium oxidation for treatment of ammonium-rich wastewaters

The concept of anaerobic ammonium oxidation (ANAMMOX) is presently of great interest. The functional bacteria belonging to the Planctomycete phylum and their metabolism are investigated by microbiologists. Meanwhile, the ANAMMOX is equally valuable in treatment of ammonium-rich wastewaters. Related processes including partial nitritation-ANAMMOX and completely autotrophic nitrogen removal over nitrite (CANON) have been developed, and lab-scale experiments proved that both processes were quite feasible in engineering with appropriate control. Successful full-scale practice in the Netherlands will accelerate application of the process in future. This review introduces the microbiology and more focuses on application of the ANAMMOX process. Project supported by the National Hi-Tech Research and Development Program (863) of China (No. 2006AA06Z332), and the Science and Technology Foundation for Key Project of Zhejiang Province (No. 2003C13005), China