Evaluation and optimization of secondary water supply system renovation

Due to pollution in second water supply system (SWSS),nine renovation alternative plans were proposed and com-prehensive evaluations of different plan based on Analytical Hierarchy Process (AHP) were presented in this paper. Comparisons of advantages and disadvantages among the plans of SWSS renovations provided solid foundation for selecting the most appro-priate plan for engineering projects. In addition,a mathematical model of the optimal combination of renovation plans has been set up and software Lingo was used to solve the model. As a case study,the paper analyzed 15 buildings in Tianjin City. After simulation of the SWSS renovation system,an optimal scheme was obtained,the result of which indicates that 10 out of those 15 buildings need be renovated in priority. The renovation plans selected for each building are the ones ranked higher in the com-prehensive analysis. The analysis revealed that the optimal scheme,compared with two other randomly calculated ones,increased the percentage of service population by 19.6% and 13.6% respectively,which significantly improved social and economical benefits.     

基于知识螺旋增长模型的知识联盟作用机理探究——以传媒领域内容联盟为例

首先界定了知识联盟的内涵,揭示出它优于一般战略联盟的特点.并以自2006年以来传媒领域的内容联盟实践为切入点,进一步探讨了构建知识联盟的条件.在此基础上,以知识的螺旋增长模型为视角,提出了传媒知识联盟内各主体的内容创新以及经营模式创新的作用机理.最后,对知识联盟创新策略及可能存在的障碍等问题提出了一些见解.     

跨组织的知识创新网络研究

基于知识创新和生物进化理论,提出跨组织知识创新进化模型,给出建立跨组织知识创新网络的切入点,结合其影响因素,将跨组织知识创新网络分类为丰田网络和硅谷网络,并进一步讨论这两种典型网络在知识创新上的优势和挑战.     

Paint on the Great Wall, Embrace the Olympics

Early in August, on Badaling Pass of the Great Wall in the northern suburb of Beijing, 500 children from Hong Kong and 200 children from Beijing participated in the opening ceremony of “Paint on the Great Wall, Embrace the Olympics”, a large-scale cultural exchange event jointly sponsored by Chinese Cultural Ministry, Beijing Municipality and Hong Kong Civil Service Bureau.     

Terminal Container Logistics:An Overview

Container logistics is an important part of logistics. The study in this field is gaining more and more attention in the scientific area. This paper introduces the concept of container logisdcs, then, analyses the characteristics and the decision problems of container logistics through a terminal. Furthermore, literature related to container logistics is presented. Finally, conclusions and suggestions are discussed.     

精英主义教育体制与重点学校

本认为,重点学校的建立是我国改革开放后学校教育重要的教育制度选择,其所引起的学校两极分化,典型地形成了精英主义的教育建制。精英主义的教育体制不公正地分配教育资源和机会,把学生分成三六九等,形成等级化的教育体制,致使多数学生在学校中处于发展的不利地位。本根据正义原则,认为任何社会公民的个性的张扬与发展都是社会福祉的因素,在基础教育阶段,不平等地分配教育资源是不公正的。教育作为培养理性的公民的机制     

一种企业技术创新能力评价的新方法

本文在对传统的企业技术创新能力及其评价思路进行分析的基础上,根据企业技术创新的实现过程,提出了企业技术创新能力定义、评价指标体系和评价方法,以期对企业的技术创新活动的有效实现提供借鉴。     

面向知识经济的企业管理创新主体研究

21世纪将是知识经济时代,创新是知识经济发展的灵魂,企业只有不断地进行管理创新,才能在新世纪从容应对各种挑战,把握宝贵的发展,本文以知识所引发的企业管理变化为背景,提出管理创新主体是由企业家,内企业家和知识工人三部分所构成的有机整体,据此分析了管理创新主体的结构功能。     

教育的多元价值取向与公民的培养

教育作为公民教育的机构 ,它的公共领域的活动性质使它既关注社会的共同利益 ,又关注全部公民的教育权利与需求 ,即教育要尽可能地人性化和多元化 ,在价值取向上要尊重个人权利与人的自由发展。通过个人品质的培养从而实现个人与社会的双重目的。教育培养公民是实现个人价值与社会价值统一的根本方式。     

Two unrelated patients with rare Crigler-Najjar syndrome type I: two novel mutations and a patient with loss of heterozygosity of UGT1A1 gene

Crigler-Najjar syndrome type I (CN-I) is the most severe type of hereditary unconjugated hyperbilirubinemia. It is caused by homozygous or compound heterozygous mutations of the UDP-glycuronosyltransferase gene (UGT1A1) on chromosome 2q37. Two patients clinically diagnosed with CN-I were examined in this paper. We sequenced five exons and their flanking sequences, specifically the promoter region of UGT1A1, of the two patients and their parents. Quantitative real-time polymerase chain reaction (qRT-PCR) was used to determine the UGT1A1 gene copy number of one patient. In patient A, two mutations, c.239_245delCTGTGCC (p.Pro80HisfsX6; had not been reported previously) and c.1156G>T (p.Val386Phe), were identified. In patient B, we found that this patient had lost heterozygosity of the UGT1A1 gene by inheriting a deletion of one allele, and had a novel mutation c.1253delT (p.Met418ArgfsX5) in the other allele. In summary, we detected three UGT1A1 mutations in two CN-I patients: c.239_245delCTGTGCC (p.Pro80HisfsX6), c.1253delT (p.Met418ArgfsX5), and c.1156G>T (p.Val386Phe). The former two mutations are pathogenic; however, the pathogenic mechanism of c.1156G>T (p.Val386Phe) is unknown.