Holistic information behavior and the perceived success of work in organizations

Surprisingly little is known about the relationship between perceived work success and information behavior. This study shows that holistic (versus organization-centric) information behavioral preferences are related to interaction and exchange oriented perceptions of the success of work. The findings were drawn from a partial least square structural equation modeling (PLS-SEM) based analysis of the survey data (N?=?305) collected from employees of a large multinational corporation. The findings suggest that holistic information behavior is more strongly related to social measures of success, whereas their association with quantitative measures tends to be lower. From the perspective of information behavior research, the findings suggest that holism seems to be a similar factor to, for instance, task complexity or personality, which influences human information behavior and, for instance, perceptions of relevance. From a practical perspective, the study suggests that the promotion of specific facets of measuring success and patterns of information behavior can be used to influence the orientation of working between centrifugality and openness.     

A CRISPR/Cas12a-empowered surface plasmon resonance platform for rapid and specific diagnosis of the Omicron variant of SARS-CoV-2

The outbreak of the COVID-19 pandemic was partially due to the challenge of identifying asymptomatic and presymptomatic carriers of the virus, and thus highlights a strong motivation for diagnostics with high sensitivity that can be rapidly deployed. On the other hand, several concerning SARS-CoV-2 variants, including Omicron, are required to be identified as soon as the samples are identified as ‘positive’. Unfortunately, a traditional PCR test does not allow their specific identification. Herein, for the first time, we have developed MOPCS (Methodologies of Photonic CRISPR Sensing), which combines an optical sensing technology-surface plasmon resonance (SPR) with the ‘gene scissors’ clustered regularly interspaced short palindromic repeat (CRISPR) technique to achieve both high sensitivity and specificity when it comes to measurement of viral variants. MOPCS is a low-cost, CRISPR/Cas12a-system-empowered SPR gene-detecting platform that can analyze viral RNA, without the need for amplification, within 38 min from sample input to results output, and achieve a limit of detection of 15 fM. MOPCS achieves a highly sensitive analysis of SARS-CoV-2, and mutations appear in variants B.1.617.2 (Delta), B.1.1.529 (Omicron) and BA.1 (a subtype of Omicron). This platform was also used to analyze some recently collected patient samples from a local outbreak in China, identified by the Centers for Disease Control and Prevention. This innovative CRISPR-empowered SPR platform will further contribute to the fast, sensitive and accurate detection of target nucleic acid sequences with single-base mutations.     

Iraqi,Syrian, and Palestinian Refugee Adolescents' Beliefs About Parental Authority Legitimacy and Its Correlates

This study examined intra‐ and interindividual variations in parental legitimacy beliefs in a sample of 883 Arab refugee adolescents (M_age = 15.01 years, SD = 1.60), 277 Iraqis, 275 Syrians, and 331 Palestinians in Amman, Jordan. Confirmatory factor analyses showed distinct latent factors for moral–conventional, prudential, and personal legitimacy items. Older adolescents rated legitimacy lower for personal issues, but higher for prudential issues. Beliefs were associated with socioeconomic status (fathers' education, family size), particularly for personal issues, but were more pervasively associated with displacement‐related experiences. Greater war trauma was associated with less prudential legitimacy for all youth and more authority legitimacy over moral–conventional issues for Syrian youth. Greater hopefulness was associated with more authority legitimacy over all but personal issues.     

Examining the antecedents of e-loyalty intention in an online reservation environment

Online reservation has increased significantly in recent years. Understanding how customers behave towards this technology is considered to be important to interested parties, such as travel agencies and tourism marketing managers, in order to enable them to improve their marketing strategies, which would, in turn, allow them to retain their customers. This paper presents findings about the antecedents of e-loyalty intention towards online reservation among 288 respondents in the United Arab Emirates. The research examines the role of e-service quality, hedonic and utilitarian values, satisfaction, and subjective norms in motivating loyalty intention towards online reservation. The results show that e-service quality has a significant influence on hedonic and utilitarian values, which, in turn, affect customer satisfaction. Moreover, satisfaction and subjective norms positively affect e-loyalty intention towards online reservation.     

Ladder realizations of multivariable positive real functions

Necessary and sufficient conditions are obtained for the realization of an m-variable positive real function (PRF) as the impedence function of a resistively-terminated ladder network of m lossless two-ports connected in cascade. Each two-port is a single-variable lossless ladder with all of its transmission zeros either at the origin or at finity. Conditions are also obtained when each of the two-ports is a Fujisawa-type lowpass ladder.     

Maximal lactate steady state in trained adolescent runners

The aims of this study were: (1) to identify the exercise intensity that corresponds to the maximal lactate steady state in adolescent endurance-trained runners; (2) to identify any differences between the sexes; and (3) to compare the maximal lactate steady state with commonly cited fixed blood lactate reference parameters. Sixteen boys and nine girls volunteered to participate in the study. They were first tested using a stepwise incremental treadmill protocol to establish the blood lactate profile and peak oxygen uptake ([Vdot]O₂). Running speeds corresponding to fixed whole blood lactate concentrations of 2.0, 2.5 and 4.0?mmol?·?l^?1 were calculated using linear interpolation. The maximal lactate steady state was determined from four separate 20-min constant-speed treadmill runs. The maximal lactate steady state was defined as the fastest running speed, to the nearest 0.5?km?·?h^?1, where the change in blood lactate concentration between 10 and 20?min was?<0.5?mmol?·?l^?1. Although the boys had to run faster than the girls to elicit the maximal lactate steady state (15.7 vs 14.3?km?·?h^?1, P?<0.01), once the data were expressed relative to percent peak [Vdot]O₂ (85 and 85%, respectively) and percent peak heart rate (92 and 94%, respectively), there were no differences between the sexes (P?>0.05). The running speed and percent peak [Vdot]O₂ at the maximal lactate steady state were not different to those corresponding to the fixed blood lactate concentrations of 2.0 and 2.5?mmol?·?l^?1 (P?>0.05), but were both lower than those at the 4.0?mmol?·?l^?1 concentration (P?<0.05). In conclusion, the maximal lactate steady state corresponded to a similar relative exercise intensity as that reported in adult athletes. The running speed, percent peak [Vdot]O₂ and percent peak heart rate at the maximal lactate steady state are approximated by the fixed blood lactate concentration of 2.5?mmol?·?l^?1 measured during an incremental treadmill test in boys and girls.     

Antioxidants in aqueous extract of Myristica fragrans (Houtt.) suppress mitosis and cyclophosphamide-induced chromosomal aberrations in Allium cepa L. cells

In this study, freeze-dried water extract from the leaves of Myristica fragrans (Houtt.) was tested for mutagenic and antimutagenic potentials using the Allium cepa assay. Freeze-dried water extract alone and its combination with cyclophosphamide (CP) (50 mg/kg) were separately dissolved in tap water at 500, 1000, 2000, and 4000 mg/kg. Onions (A. cepa) were suspended in the solutions and controls for 48 h in the dark. Root tips were prepared for microscopic evaluation. 2,2-Diphenyl-1-picrylhydrazyl (DPPH) free radicals’ scavenging power of the extract was tested using butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) as standards. Water extract of Myristica fragrans scavenged free radicals better than BHA, but worse than BHT. The extract alone, as well as in combination with CP suppressed cell division, and induced chromosomal aberrations that were insignificantly different from the negative control (P≤0.05). However, cytotoxic and mutagenic actions of CP were considerably suppressed. The observed effects on cell division and chromosomes of A. cepa may be principally connected to the antioxidant properties of the extract. The obtained results suggest mitodepressive and antimutagenic potentials of water extract of the leaves of M. fragrans as desirable properties of a promising anticancer agent.