Quantum pharmacology

Quantum chemistry is based on the solution of the Schrödinger equation for a molecule. From starting data on the positions and nature of constituent atoms information is provided about the energy of the molecule and its electronic properties. The former can indicate what shapes drugs can adopt in binding to pharmacological receptors whilst electronic details, when compared using computer graphics, may highlight the factors responsible for biological activity. These techniques are beginning to show real successes in the design of drug molecules.     

A cost comparison of manual and automated circulation systems in university libraries: The case of the Ibadan University library

This paper presents the results of a comparative cost study of the manual circulation system and experimental automated system in a university library in Nigeria. Two sets of data were collected: one on the existing manual circulation system and the other on the experimental automated system on an Apple II microcomputer. Eight different circulation activities were identified for evaluation for which the direct labor cost of circulating a book on each system was calculated. The experimental automated system was found to be less labor intensive than the manual system, although overall unit cost of book circulation on the automated system was higher than on the manual system ($0.59 and $0.49, respectively). Factors attributed to the higher unit cost on the automated system were the cost of equipment and the low circulation figure. However, the automated system was found to be more effective in providing up-to-date and accurate data required for the monitoring of the library stock.     

From divergent meanings to common practices: The early institutionalization of technology transfer in the life sciences at Stanford University

The formation of Stanford University's technology transfer program in the life sciences is analyzed from 1968 to 1982. The program evolved from multiple models based on divergent definitions of invention, inventor, rewards, and university-industry boundaries. The eventual program that emerged proved to be widely emulated. The norms of the academy shaped the uses of resources and the conditions of their appropriation. In turn, the currency of industrial science prompted the rethinking of academic norms. The analysis offers insight into the early stages of institutionalization, as the ambiguity of important categories and flexibility of policies were transformed into organizational routines. Today's ‘settled’ outcomes are the product of highly divergent practices.     

Ethics and technology design

This article offers a discussion of the connection between technology and values and, specifically, I take a closer look at ethically sound design. In order to bring the discussion into a concrete context, the theory of Value Sensitive Design (VSD) will be the focus point. To illustrate my argument concerning design ethics, the discussion involves a case study of an augmented window, designed by the VSD Research Lab, which has turned out to be a potentially surveillance-enabling technology. I call attention to a “positivist problem” that has to do with the connection between the design context and the use context, which VSD seems to presuppose, and I argue that it is necessary to clearly distinguish between the two, since the designers’ intentions do not always correspond with the users’ practice; in fact, the relation between design and use is very complex and principally unpredictable. Thus, a design theory must accept that foresight is limited to anticipation rather than prediction. To overcome the positivist problem, I suggest a phenomenological approach to technology inspired by Don Ihde’s concept of multistability. This argument, which is general in nature and thus applies to any theory of design ethics, is intended as a constructive criticism, which can hopefully contribute to the further development of design ethics.