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501.
Jørgen Ingebrigtsen Mads Bendiksen Morten Bredsgaard Randers Carlo Castagna Peter Krustrup Andreas Holtermann 《Journal of sports sciences》2013,31(13):1337-1345
Abstract We examined performance, heart rate response and construct validity of the Yo-Yo IR2 test by testing 111 elite and 92 sub-elite soccer players from Norway and Denmark. VO2max, Yo-Yo IR1 and repeated sprint tests (RSA) (n = 51) and match-analyses (n = 39) were also performed. Yo-Yo IR2 and Yo-Yo IR1 performance was 41 and 25% better (P < 0.01) for elite than sub-elite players, respectively, and heart rate after 2 and 4 min of the Yo-Yo IR2 test was 20 and 15 bpm (9 and 6% HRmax), respectively, lower (P < 0.01) for elite players. RSA performance and VO2max was not different between competitive levels (P > 0.05). For top-teams, Yo-Yo IR2 performance (28%) and sprinting distance (25%) during match were greater (P < 0.05) than for bottom-teams. For elite and sub-elite players, Yo-Yo IR2 performance was correlated (P < 0.05) with Yo-Yo IR1 performance (r = 0.74 and 0.76) and mean RSA time (r = ?0.74 and ?0.34). We conclude that the Yo-Yo IR2 test has a high discriminant and concurrent validity, as it discriminates between players of different within- and between-league competitive levels and is correlated to other frequently used intermittent elite soccer tests. 相似文献
502.
Svein Barene Peter Krustrup Ole Lars Brekke Andreas Holtermann 《Journal of sports sciences》2013,31(16):1539-1549
AbstractThe aim of this study was to evaluate the physiological effects of soccer and Zumba among female hospital employees during a 40-week intervention period. Hospital employees (n = 118) were cluster-randomised to either a soccer group (n = 41), a Zumba group (n = 38) or a control group (n = 39). Both training groups were encouraged to perform 1-h training sessions twice a week outside working hours throughout the 40 weeks. Maximal oxygen uptake (VO2 max), blood pressure and body composition were measured and blood samples collected before and after the intervention period. Using intention-to-treat analyses, the Zumba group improved VO2 max compared to the control group (2.2 mL · kg?1 · min?1, 95% CI, 0.9, 3.5, P = 0.001), with no significant increase in the soccer group (1.1 mL · kg?1 · min?1, 95% CI, ?0.2, 2.4, P = 0.08). Both intervention groups reduced total body fat mass and fat percentage compared to the control group (P < 0.01). In the soccer group, but not the Zumba group, a significant difference in lower limb bone mineral density and bone mineral content was observed in comparison to the control group (P < 0.01). Furthermore, the soccer group, but not the Zumba group, had increased plasma osteocalcin (6.6 µg · L?1, 95% CI, 2.2, 11.0, P < 0.01) and decreased plasma leptin (?6.6 µg · L?1, 95% CI, ?12.5, ?0.7, P < 0.05) compared to the control group. The present study suggests that workplace-initiated soccer and Zumba training comprising 1–2 sessions per week outside working hours may promote physiological health among female hospital employees. 相似文献
503.
Wibke Johannis Jenny Blommer Andreas R. Klatt Joerg H. Renno Klaus Wielckens 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2012,22(3):373-379
Introduction:
Heavy chain diseases (HCD) are neoplastic proliferations of B cells which secrete truncated immunoglobulin heavy chains without associated light chains. Being rare and probably underdiagnosed diseases the aim of this report is to show an additional case of gamma heavy chain disease in a 48 year old female patient with rheumatoid arthritis focusing on the laboratory presentation.Materials and methods:
Laboratory work-up included agarose gel electrophoresis (AGE), capillary zone electrophoresis (CZE), immunofixation and nephelometrically determined immunoglobulin and immunoglobulin subclasses of the patient’s serum. Urine samples were also subjected to immunofixation and to a SDS-PAGE with consecutive immunoblot.Results:
Nephelometrically measured elevated IgG concentrations were noted in combination with a decreased gamma globulin region and an increased beta globulin region on AGE. A definite monoclonal spike was not identified on AGE but at least suspected on CZE; finally serum and urine immunofixation demonstrated a monoclonal gamma heavy chain devoid of any corresponding light chains confirming the diagnosis of HCD. Analysis of the gamma heavy chain (HC) with means of SDS-PAGE revealed proteins of 40 kD and 80 kD most likely presenting a truncated HC in its monomeric and dimeric form and possibly leading to the failure of IgG-subclass typing with the applied IgG subclass antisera.Conclusion:
This case report illustrates a new case of gamma HCD demonstrating variable laboratory manifestations and therefore the need for heightened awareness concerning this disease when confronted with abnormal and discrepant protein profiles in routinely applied laboratory tests. 相似文献504.
Homsy A van der Wal PD Doll W Schaller R Korsatko S Ratzer M Ellmerer M Pieber TR Nicol A de Rooij NF 《Biomicrofluidics》2012,6(1):12804-128049
Clinical point of care testing often needs plasma instead of whole blood. As centrifugation is labor intensive and not always accessible, filtration is a more appropriate separation technique. The complexity of whole blood is such that there is still no commercially available filtration system capable of separating small sample volumes (10-100 μl) at the point of care. The microfluidics research in blood filtration is very active but to date nobody has validated a low cost device that simultaneously filtrates small samples of whole blood and reproducibly recovers clinically relevant biomarkers, and all this in a limited amount of time with undiluted raw samples. In this paper, we show first that plasma filtration from undiluted whole blood is feasible and reproducible in a low-cost microfluidic device. This novel microfluidic blood filtration element (BFE) extracts 12 μl of plasma from 100 μl of whole blood in less than 10 min. Then, we demonstrate that our device is valid for clinical studies by measuring the adsorption of interleukins through our system. This adsorption is reproducible for interleukins IL6, IL8, and IL10 but not for TNFα. Hence, our BFE is valid for clinical diagnostics with simple calibration prior to performing any measurement. 相似文献
505.
J Ingebrigtsen M Bendiksen MB Randers C Castagna P Krustrup A Holtermann 《Journal of sports sciences》2012,30(13):1337-1345
Abstract We examined performance, heart rate response and construct validity of the Yo-Yo IR2 test by testing 111 elite and 92 sub-elite soccer players from Norway and Denmark. VO(2)max, Yo-Yo IR1 and repeated sprint tests (RSA) (n?=?51) and match-analyses (n?=?39) were also performed. Yo-Yo IR2 and Yo-Yo IR1 performance was 41 and 25% better (P?0.01) for elite than sub-elite players, respectively, and heart rate after 2 and 4 min of the Yo-Yo IR2 test was 20 and 15 bpm (9 and 6% HRmax), respectively, lower (P?0.01) for elite players. RSA performance and VO(2)max was not different between competitive levels (P?>?0.05). For top-teams, Yo-Yo IR2 performance (28%) and sprinting distance (25%) during match were greater (P?0.05) than for bottom-teams. For elite and sub-elite players, Yo-Yo IR2 performance was correlated (P?0.05) with Yo-Yo IR1 performance (r?=?0.74 and 0.76) and mean RSA time (r?=?-0.74 and -0.34). We conclude that the Yo-Yo IR2 test has a high discriminant and concurrent validity, as it discriminates between players of different within- and between-league competitive levels and is correlated to other frequently used intermittent elite soccer tests. 相似文献
506.
507.
Ernst A. Hany 《High Ability Studies》1996,7(1):65-82
The contribution of leisure time activities to highly intelligent people's creative achievement has rarely been investigated. By using highly intelligent adults' (N = 246) retrospective estimates of frequencies of leisure time activities, a special developmental profile of leisure time usage was found for the more successful individuals in contrast to the less successful. Highly intelligent, successful individuals spent more of their free time on self‐realizing activities, like demanding hobbies, making music or engaging actively in sports, both during adolescence and in later years, and they showed a rising frequency of intellectually demanding activities with growing age. The results can be interpreted in terms of the expert‐novice framework, the problem solving approach to creative thinking, and in terms of the developing identity of young people.
508.
509.
European Citizens under Construction: The Bologna process analysed from a governmentality perspective 总被引:1,自引:0,他引:1
This article focuses on problematizing the harmonisation of higher education in Europe today. The overall aim is to analyse the construction of the European citizen and the rationality of governing related to such a construction. The specific focus will be on the rules and standards of reason in higher education reforms which inscribe continuums of values that exclude as they include. Who is and who is not constructed as a European citizen? Documents on the Bologna process produced in Europe and in Sweden are analysed drawing on the Foucauldian notion of governmentality, showing a neoliberal rationality of governing. The European citizen needs to become flexible, autonomous and self-regulating as a way of facing the threats of the constantly changing future. The technique of diversity is a condition of possibility for constructing such a citizen and for harmonising higher education in Europe. Further, the current power relations in the discourse define what is and what is not European, thus constructing 'the other', the one who is excluded. 相似文献
510.